mirtazapine has been researched along with Emesis in 14 studies
Mirtazapine: A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Background We examined the efficacy of mirtazapine in preventing delayed nausea and vomiting following highly emetogenic chemotherapy (HEC)." | 9.34 | Mirtazapine, a dopamine receptor inhibitor, as a secondary prophylactic for delayed nausea and vomiting following highly emetogenic chemotherapy: an open label, randomized, multicenter phase III trial. ( Cao, J; Hu, X; Ouyang, Q; Ragaz, J; Shao, Z; Teng, Y; Wang, B; Wang, L; Wang, S; Wang, X; Wang, Z; Wu, J; Zhang, J, 2020) |
| "The antagonism of 5-HT3 receptor by mirtazapine results in an antiemetic effect, suggesting that mirtazapine could be considered a successful antiemetic agent in patients suffering from severe nausea and vomiting." | 7.73 | Low-dose mirtazapine may be successful treatment option for severe nausea and vomiting. ( Pae, CU, 2006) |
| "Background We examined the efficacy of mirtazapine in preventing delayed nausea and vomiting following highly emetogenic chemotherapy (HEC)." | 5.34 | Mirtazapine, a dopamine receptor inhibitor, as a secondary prophylactic for delayed nausea and vomiting following highly emetogenic chemotherapy: an open label, randomized, multicenter phase III trial. ( Cao, J; Hu, X; Ouyang, Q; Ragaz, J; Shao, Z; Teng, Y; Wang, B; Wang, L; Wang, S; Wang, X; Wang, Z; Wu, J; Zhang, J, 2020) |
| "Cats with chronic kidney disease (CKD) often experience inappetence and vomiting and might benefit from the administration of mirtazapine, a medication with appetite stimulant and anti-nausea properties." | 5.17 | Mirtazapine as an appetite stimulant and anti-emetic in cats with chronic kidney disease: a masked placebo-controlled crossover clinical trial. ( Lunn, KF; Quimby, JM, 2013) |
| "The antagonism of 5-HT3 receptor by mirtazapine results in an antiemetic effect, suggesting that mirtazapine could be considered a successful antiemetic agent in patients suffering from severe nausea and vomiting." | 3.73 | Low-dose mirtazapine may be successful treatment option for severe nausea and vomiting. ( Pae, CU, 2006) |
| "Mirtazapine was administered to 50 cancer patients with digestive symptoms in palliative care, and the data were retrospectively examined." | 1.40 | [Effectiveness of mirtazapine for digestive symptoms in palliative care - retrospective study of 50 cases]. ( Imai, E; Nishimura, D; Shibahara, H; Tokura, Y; Uematsu, N, 2014) |
| "Cannabinoid hyperemesis is a cluster of symptoms characterized by chronic cannabis abuse, cyclical vomiting and compulsive bathing behaviours." | 1.34 | Cannabinoid hyperemesis: marijuana puts patients in hot water. ( Martin, AL; Park, B; Wallace, D, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Kinomura, M | 1 |
| Iihara, H | 1 |
| Fujii, H | 1 |
| Hirose, C | 1 |
| Endo, J | 1 |
| Yanase, K | 1 |
| Inui, T | 1 |
| Kaito, D | 1 |
| Sasaki, Y | 1 |
| Gomyo, T | 1 |
| Sakai-Masuda, C | 1 |
| Kawae, D | 1 |
| Kitamura, YU | 1 |
| Fukui, M | 1 |
| Kobayashi, R | 1 |
| Ohno, Y | 1 |
| Suzuki, A | 1 |
| Cao, J | 1 |
| Ouyang, Q | 1 |
| Wang, S | 1 |
| Ragaz, J | 1 |
| Wang, X | 1 |
| Teng, Y | 1 |
| Wang, B | 1 |
| Wang, Z | 1 |
| Zhang, J | 1 |
| Wang, L | 1 |
| Wu, J | 1 |
| Shao, Z | 1 |
| Hu, X | 1 |
| Park, JI | 1 |
| Quimby, JM | 1 |
| Lunn, KF | 1 |
| Shibahara, H | 1 |
| Uematsu, N | 1 |
| Imai, E | 1 |
| Tokura, Y | 1 |
| Nishimura, D | 1 |
| Kundu, S | 1 |
| Rogal, S | 1 |
| Alam, A | 1 |
| Levinthal, DJ | 1 |
| Otera, M | 1 |
| Machida, T | 2 |
| Abe, M | 1 |
| Ichie, M | 1 |
| Fukudo, S | 1 |
| Bondade, S | 1 |
| Basavaraju, V | 1 |
| Singh, N | 1 |
| Hoşoğlu, E | 1 |
| Hergüner, S | 1 |
| Omay, O | 1 |
| Einarson, A | 1 |
| Raji, MA | 1 |
| Pae, CU | 1 |
| Wallace, D | 1 |
| Martin, AL | 1 |
| Park, B | 1 |
| Spierings, EL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase III Trial Comparing Dexamethasone, Aprepitant With or Without Mirtazapine in Delayed Emesis Control and Appetite Improvement[NCT02336750] | Phase 3 | 212 participants (Actual) | Interventional | 2014-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for mirtazapine and Emesis
| Article | Year |
|---|---|
Mirtazapine, a dopamine receptor inhibitor, as a secondary prophylactic for delayed nausea and vomiting following highly emetogenic chemotherapy: an open label, randomized, multicenter phase III trial.
Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Breast Neoplasms; Cisplatin | 2020 |
Mirtazapine as an appetite stimulant and anti-emetic in cats with chronic kidney disease: a masked placebo-controlled crossover clinical trial.
Topics: Animals; Anorexia; Antiemetics; Appetite Stimulants; Cat Diseases; Cats; Cross-Over Studies; Female; | 2013 |
12 other studies available for mirtazapine and Emesis
| Article | Year |
|---|---|
Effect of Mirtazapine for the Prevention of Nausea and Vomiting in Patients With Thoracic Cancer Receiving Platinum-based Chemotherapy.
Topics: Antiemetics; Carboplatin; Humans; Mirtazapine; Nausea; Platinum; Retrospective Studies; Serotonin; T | 2023 |
Rapid improvement of functional nausea and vomiting with mirtazapine in an elderly patient.
Topics: Aged; Antidepressive Agents; Depressive Disorder; Female; Humans; Mirtazapine; Nausea; Somatoform Di | 2019 |
[Effectiveness of mirtazapine for digestive symptoms in palliative care - retrospective study of 50 cases].
Topics: Adult; Aged; Aged, 80 and over; Feeding and Eating Disorders; Female; Humans; Male; Mianserin; Middl | 2014 |
Rapid improvement in post-infectious gastroparesis symptoms with mirtazapine.
Topics: Abdominal Pain; Adrenergic alpha-Antagonists; Adult; Antiemetics; Female; Gastric Emptying; Gastropa | 2014 |
Pharmacological and psychosomatic treatments for an elderly patient with severe nausea and vomiting in reaction to postoperative stress.
Topics: Aged; Amoxapine; Anti-Anxiety Agents; Antidepressive Agents; Antiemetics; Benzodiazepines; Bromazepa | 2015 |
Use of mirtazapine in functional vomiting.
Topics: Adult; Antidepressive Agents, Tricyclic; Female; Humans; Mianserin; Mirtazapine; Nausea; Vomiting | 2016 |
Childhood Sleep Terror and Mirtazapine.
Topics: Antidepressive Agents, Tricyclic; Child; Humans; Male; Mianserin; Mirtazapine; Night Terrors; Treatm | 2016 |
Is Mirtazapine an Effective Treatment for Nausea and Vomiting of Pregnancy?: A Case Series.
Topics: Adult; Antidepressive Agents; Female; Humans; Mirtazapine; Nausea; Pregnancy; Pregnancy Complication | 2017 |
Management of chemotherapy-induced side-effects.
Topics: Antiemetics; Antineoplastic Agents; Histamine H1 Antagonists; Humans; Mianserin; Mirtazapine; Nausea | 2005 |
Low-dose mirtazapine may be successful treatment option for severe nausea and vomiting.
Topics: Adult; Antiemetics; Depressive Disorder; Humans; Korea; Male; Mianserin; Mirtazapine; Nausea; Vomiti | 2006 |
Cannabinoid hyperemesis: marijuana puts patients in hot water.
Topics: Abdominal Pain; Adult; Antidepressive Agents, Tricyclic; Cannabinoids; Cognitive Behavioral Therapy; | 2007 |
Acute and chronic hypertensive headache and hypertensive encephalopathy.
Topics: Acute Disease; Antidepressive Agents; Antihypertensive Agents; Anxiety; Arterioles; Cerebral Arterie | 2002 |