Page last updated: 2024-10-31

mirtazapine and Diffuse Myofascial Pain Syndrome

mirtazapine has been researched along with Diffuse Myofascial Pain Syndrome in 6 studies

Mirtazapine: A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the efficacy and safety of mirtazapine in Japanese patients with fibromyalgia (FM), a parallel-group, randomized, double-blind, placebo-controlled phase IIa study was conducted at 57 sites between November 2012 and February 2014."9.22Efficacy of mirtazapine for the treatment of fibromyalgia without concomitant depression: a randomized, double-blind, placebo-controlled phase IIa study in Japan. ( Miki, K; Murakami, M; Oka, H; Onozawa, K; Osada, K; Yoshida, S, 2016)
" Eighteen patients had at least moderate depression before mirtazapine treatment and 8 patients presented mild depressive symptoms."9.11Open trial of mirtazapine in patients with fibromyalgia. ( Lezanska-Szpera, M; Rybakowski, JK; Samborski, W, 2004)
"To assess the efficacy, tolerability and safety of the tetracyclic antidepressant, mirtazapine, compared with placebo or other active drug(s) in the treatment of fibromyalgia in adults."8.98Mirtazapine for fibromyalgia in adults. ( Bernardy, K; Derry, S; Häuser, W; Moore, RA; Welsch, P, 2018)
"On the background of a restricted armamentarium of drugs available for the management of fibromyalgia (FM), we aimed to compare the real-world effectiveness of two serotonin-norepinephrine reuptake inhibitors (SNRIs), mirtazapine (MTZ) and duloxetine (DLX) in FM."8.12Effectiveness and adverse effects of the use of mirtazapine as compared to duloxetine for fibromyalgia: real-life data from a retrospective cohort. ( Ahmed, S; Basu, A; Mehta, P, 2022)
" Study durations ranged from 6 to 13 weeks and studies used varying dosing strategies for mirtazapine."6.58The role of mirtazapine in patients with fibromyalgia: a systematic review. ( Brown, JN; Ottman, AA; Warner, CB, 2018)
"To evaluate the efficacy and safety of mirtazapine in Japanese patients with fibromyalgia (FM), a parallel-group, randomized, double-blind, placebo-controlled phase IIa study was conducted at 57 sites between November 2012 and February 2014."5.22Efficacy of mirtazapine for the treatment of fibromyalgia without concomitant depression: a randomized, double-blind, placebo-controlled phase IIa study in Japan. ( Miki, K; Murakami, M; Oka, H; Onozawa, K; Osada, K; Yoshida, S, 2016)
" Eighteen patients had at least moderate depression before mirtazapine treatment and 8 patients presented mild depressive symptoms."5.11Open trial of mirtazapine in patients with fibromyalgia. ( Lezanska-Szpera, M; Rybakowski, JK; Samborski, W, 2004)
"To assess the efficacy, tolerability and safety of the tetracyclic antidepressant, mirtazapine, compared with placebo or other active drug(s) in the treatment of fibromyalgia in adults."4.98Mirtazapine for fibromyalgia in adults. ( Bernardy, K; Derry, S; Häuser, W; Moore, RA; Welsch, P, 2018)
"On the background of a restricted armamentarium of drugs available for the management of fibromyalgia (FM), we aimed to compare the real-world effectiveness of two serotonin-norepinephrine reuptake inhibitors (SNRIs), mirtazapine (MTZ) and duloxetine (DLX) in FM."4.12Effectiveness and adverse effects of the use of mirtazapine as compared to duloxetine for fibromyalgia: real-life data from a retrospective cohort. ( Ahmed, S; Basu, A; Mehta, P, 2022)
" Study durations ranged from 6 to 13 weeks and studies used varying dosing strategies for mirtazapine."2.58The role of mirtazapine in patients with fibromyalgia: a systematic review. ( Brown, JN; Ottman, AA; Warner, CB, 2018)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Mehta, P1
Basu, A1
Ahmed, S1
Ottman, AA1
Warner, CB1
Brown, JN1
Welsch, P1
Bernardy, K1
Derry, S1
Moore, RA1
Häuser, W1
Miki, K1
Murakami, M1
Oka, H1
Onozawa, K1
Yoshida, S1
Osada, K1
Samborski, W2
Lezanska-Szpera, M2
Rybakowski, JK2

Reviews

2 reviews available for mirtazapine and Diffuse Myofascial Pain Syndrome

ArticleYear
The role of mirtazapine in patients with fibromyalgia: a systematic review.
    Rheumatology international, 2018, Volume: 38, Issue:12

    Topics: Fibromyalgia; Health Status; Humans; Mirtazapine; Neurotransmitter Agents; Pain Threshold; Quality o

2018
Mirtazapine for fibromyalgia in adults.
    The Cochrane database of systematic reviews, 2018, 08-06, Volume: 8

    Topics: Adult; Antidepressive Agents, Tricyclic; Fibromyalgia; Humans; Mianserin; Mirtazapine; Randomized Co

2018

Trials

3 trials available for mirtazapine and Diffuse Myofascial Pain Syndrome

ArticleYear
Efficacy of mirtazapine for the treatment of fibromyalgia without concomitant depression: a randomized, double-blind, placebo-controlled phase IIa study in Japan.
    Pain, 2016, Volume: 157, Issue:9

    Topics: Adult; Analysis of Variance; Antidepressive Agents, Tricyclic; Depression; Double-Blind Method; Fema

2016
Open trial of mirtazapine in patients with fibromyalgia.
    Pharmacopsychiatry, 2004, Volume: 37, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adult; Depression; Drug Administration Schedule; Female; Fibromyalgia;

2004
Effects of antidepressant mirtazapine on fibromyalgia symptoms.
    Roczniki Akademii Medycznej w Bialymstoku (1995), 2004, Volume: 49

    Topics: Adult; Antidepressive Agents, Tricyclic; Female; Fibromyalgia; Humans; Male; Mianserin; Middle Aged;

2004

Other Studies

1 other study available for mirtazapine and Diffuse Myofascial Pain Syndrome

ArticleYear
Effectiveness and adverse effects of the use of mirtazapine as compared to duloxetine for fibromyalgia: real-life data from a retrospective cohort.
    Rheumatology international, 2022, Volume: 42, Issue:9

    Topics: Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Male; Middle Aged; Mirtazapine; Retrospectiv

2022