mirtazapine has been researched along with Dermatomyositis in 2 studies
Mirtazapine: A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.
Dermatomyositis: A subacute or chronic inflammatory disease of muscle and skin, marked by proximal muscle weakness and a characteristic skin rash. The illness occurs with approximately equal frequency in children and adults. The skin lesions usually take the form of a purplish rash (or less often an exfoliative dermatitis) involving the nose, cheeks, forehead, upper trunk, and arms. The disease is associated with a complement mediated intramuscular microangiopathy, leading to loss of capillaries, muscle ischemia, muscle-fiber necrosis, and perifascicular atrophy. The childhood form of this disease tends to evolve into a systemic vasculitis. Dermatomyositis may occur in association with malignant neoplasms. (From Adams et al., Principles of Neurology, 6th ed, pp1405-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In cases of malignancy that are refractive to treatment, other therapies have been found to be effective for paraneoplastic itch, including selective serotonin reuptake inhibitors, mirtazapine, gabapentin, thalidomide, opioids, aprepitant, and histone deacetylase inhibitors." | 2.53 | Paraneoplastic Itch Management. ( Rowe, B; Yosipovitch, G, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rowe, B | 1 |
| Yosipovitch, G | 1 |
| Vulliemoz, S | 1 |
| Lurati-Ruiz, F | 1 |
| Borruat, FX | 1 |
| Delavelle, J | 1 |
| Koralnik, IJ | 1 |
| Kuntzer, T | 1 |
| Bogousslavsky, J | 1 |
| Picard, F | 1 |
| Landis, T | 1 |
| Du Pasquier, RA | 1 |
1 review available for mirtazapine and Dermatomyositis
| Article | Year |
|---|---|
Paraneoplastic Itch Management.
Topics: Acantholysis; Acanthosis Nigricans; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Apre | 2016 |
1 other study available for mirtazapine and Dermatomyositis
| Article | Year |
|---|---|
Favourable outcome of progressive multifocal leucoencephalopathy in two patients with dermatomyositis.
Topics: Adrenergic alpha-Antagonists; Cytarabine; Dermatomyositis; Female; Humans; Immunosuppressive Agents; | 2006 |