Page last updated: 2024-10-31

mirtazapine and Depressive Disorder, Treatment-Resistant

mirtazapine has been researched along with Depressive Disorder, Treatment-Resistant in 7 studies

Mirtazapine: A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.

Depressive Disorder, Treatment-Resistant: Failure to respond to two or more trials of antidepressant monotherapy or failure to respond to four or more trials of different antidepressant therapies. (Campbell's Psychiatric Dictionary, 9th ed.)

Research Excerpts

ExcerptRelevanceReference
" Here, we report the case of a 20-year-old man with severe social anxiety disorder, major depressive disorder, insomnia and attenuated psychotic symptoms despite ongoing treatment with cognitive behavioural therapy and mirtazapine who was treated with adjunctive cannabidiol (CBD) in doses between 200 and 800 mg/day for 6 months."7.96Treatment of social anxiety disorder and attenuated psychotic symptoms with cannabidiol. ( Amminger, GP; Berger, M; Li, E, 2020)
" Here, we report the case of a 20-year-old man with severe social anxiety disorder, major depressive disorder, insomnia and attenuated psychotic symptoms despite ongoing treatment with cognitive behavioural therapy and mirtazapine who was treated with adjunctive cannabidiol (CBD) in doses between 200 and 800 mg/day for 6 months."3.96Treatment of social anxiety disorder and attenuated psychotic symptoms with cannabidiol. ( Amminger, GP; Berger, M; Li, E, 2020)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (71.43)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Berger, M1
Li, E1
Amminger, GP1
Rifkin-Zybutz, R1
MacNeill, S2
Davies, SJ1
Dickens, C2
Campbell, J3
Anderson, IM2
Chew-Graham, CA2
Peters, TJ3
Lewis, G3
Wiles, N2
Kessler, D2
Kessler, DS1
MacNeill, SJ1
Tallon, D2
Hollingworth, W2
Round, J2
Burns, A2
Shepherd, T1
Dickens, CM1
Carter, M1
Jenkinson, C1
Macleod, U2
Gibson, H1
Davies, S2
Wiles, NJ1
Chew-Graham, C1
Anderson, I1
Gilbody, S1
Zeeh, J1
Simon, GE1
Rzezniczek, S1
Obuchowicz, M1
Datka, W1
Siwek, M1
Dudek, D1
Kmiotek, K1
Oved, K1
Shomron, N1
Gurwitz, D1
Pilc, A1

Trials

3 trials available for mirtazapine and Depressive Disorder, Treatment-Resistant

ArticleYear
Does anxiety moderate the effectiveness of mirtazapine in patients with treatment-resistant depression? A secondary analysis of the MIR trial.
    Journal of psychopharmacology (Oxford, England), 2020, Volume: 34, Issue:12

    Topics: Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Comorbidity; Data Interpretation, Statistical;

2020
Mirtazapine added to SSRIs or SNRIs for treatment resistant depression in primary care: phase III randomised placebo controlled trial (MIR).
    BMJ (Clinical research ed.), 2018, 10-31, Volume: 363

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Depressive Disorder, Treatment-Resistant; Drug Thera

2018
Combining mirtazapine with SSRIs or SNRIs for treatment-resistant depression: the MIR RCT.
    Health technology assessment (Winchester, England), 2018, Volume: 22, Issue:63

    Topics: Adult; Aged; Antidepressive Agents; Cost-Benefit Analysis; Depressive Disorder, Treatment-Resistant;

2018

Other Studies

4 other studies available for mirtazapine and Depressive Disorder, Treatment-Resistant

ArticleYear
Treatment of social anxiety disorder and attenuated psychotic symptoms with cannabidiol.
    BMJ case reports, 2020, Oct-07, Volume: 13, Issue:10

    Topics: Adult; Cannabidiol; Cognitive Behavioral Therapy; Depressive Disorder, Major; Depressive Disorder, T

2020
    MMW Fortschritte der Medizin, 2018, Volume: 160, Issue:21-22

    Topics: Depressive Disorder, Treatment-Resistant; Humans; Mirtazapine; Primary Health Care; Selective Seroto

2018
Adding mirtazapine to ongoing SNRIs or SSRIs did not improve symptoms of treatment-resistant depression.
    Annals of internal medicine, 2019, 02-19, Volume: 170, Issue:4

    Topics: Depression; Depressive Disorder, Treatment-Resistant; Humans; Mirtazapine; Primary Health Care; Sele

2019
Decreased sensitivity to paroxetine-induced inhibition of peripheral blood mononuclear cell growth in depressed and antidepressant treatment-resistant patients.
    Translational psychiatry, 2016, 05-31, Volume: 6, Issue:5

    Topics: Adult; Biomarkers; Cell Proliferation; Depressive Disorder, Major; Depressive Disorder, Treatment-Re

2016