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mirtazapine and Cardiac Toxicity

mirtazapine has been researched along with Cardiac Toxicity in 1 studies

Mirtazapine: A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.

Research Excerpts

ExcerptRelevanceReference
"Previous surveys have revealed that mirtazapine (MIR), one of the most commonly prescribed antidepressants, is associated with a higher risk of adverse cardiac events compared with other newer antidepressants."5.72Ethanol potentiates mirtazapine-induced cardiotoxicity by inducing dysfunctional autophagy via HMGB1-dependent Akt/mTOR signaling pathway. ( Dong, X; Jiang, Y; Liu, X; Xue, Q; Zhang, T; Zhu, R, 2022)
"Previous surveys have revealed that mirtazapine (MIR), one of the most commonly prescribed antidepressants, is associated with a higher risk of adverse cardiac events compared with other newer antidepressants."1.72Ethanol potentiates mirtazapine-induced cardiotoxicity by inducing dysfunctional autophagy via HMGB1-dependent Akt/mTOR signaling pathway. ( Dong, X; Jiang, Y; Liu, X; Xue, Q; Zhang, T; Zhu, R, 2022)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Zhu, R1
Liu, X1
Xue, Q1
Dong, X1
Zhang, T1
Jiang, Y1

Other Studies

1 other study available for mirtazapine and Cardiac Toxicity

ArticleYear
Ethanol potentiates mirtazapine-induced cardiotoxicity by inducing dysfunctional autophagy via HMGB1-dependent Akt/mTOR signaling pathway.
    Toxicology letters, 2022, Apr-01, Volume: 358

    Topics: Animals; Autophagy; Cardiotoxicity; Ethanol; HMGB1 Protein; Humans; Male; Mice; Mice, Inbred C57BL;

2022