Page last updated: 2024-10-31

mirtazapine and Cannabis Abuse

mirtazapine has been researched along with Cannabis Abuse in 3 studies

Mirtazapine: A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.

Research Excerpts

ExcerptRelevanceReference
"Cannabinoid hyperemesis is a cluster of symptoms characterized by chronic cannabis abuse, cyclical vomiting and compulsive bathing behaviours."1.34Cannabinoid hyperemesis: marijuana puts patients in hot water. ( Martin, AL; Park, B; Wallace, D, 2007)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Haney, M1
Hart, CL1
Vosburg, SK1
Comer, SD1
Reed, SC1
Cooper, ZD1
Foltin, RW1
Wallace, D1
Martin, AL1
Park, B1
Benyamina, A1
Lecacheux, M1
Blecha, L1
Reynaud, M1
Lukasiewcz, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Baclofen on Marijuana Withdrawal and Relapse[NCT00373295]Phase 213 participants (Actual)Interventional2006-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Measure of Relapse: Change in Money Spent Between Baseline and Relapse Phase

"This is a measure of marijuana self-administration and relapse since each initial puff costs $7 and is a burden to overcome just to smoke.~Over each 3 day period, the puffs chosen by each participant is averaged for a single value." (NCT00373295)
Timeframe: Days 1-3 (Baseline) and Days 6-8 (Relapse Phase)

Interventiondollars spent on marijuana (Mean)
Baclofen 60, Marijuana7.15
Placebo, Marijuana9.77
Baclofen 90, Marijuana7.25

Reviews

1 review available for mirtazapine and Cannabis Abuse

ArticleYear
Pharmacotherapy and psychotherapy in cannabis withdrawal and dependence.
    Expert review of neurotherapeutics, 2008, Volume: 8, Issue:3

    Topics: Behavior Therapy; Buspirone; Cannabinoids; Cognitive Behavioral Therapy; Combined Modality Therapy;

2008

Trials

1 trial available for mirtazapine and Cannabis Abuse

ArticleYear
Effects of baclofen and mirtazapine on a laboratory model of marijuana withdrawal and relapse.
    Psychopharmacology, 2010, Volume: 211, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adult; Affect; Baclofen; Cognition; Dose-Response Relationship, Drug;

2010

Other Studies

1 other study available for mirtazapine and Cannabis Abuse

ArticleYear
Cannabinoid hyperemesis: marijuana puts patients in hot water.
    Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists, 2007, Volume: 15, Issue:2

    Topics: Abdominal Pain; Adult; Antidepressive Agents, Tricyclic; Cannabinoids; Cognitive Behavioral Therapy;

2007