mirtazapine has been researched along with Bipolar Disorder in 25 studies
Mirtazapine: A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.
Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors report a case involving a 79-year-old woman with bipolar disorder, in whom Pisa syndrome occurred after introduction of mirtazapine, and completely disappeared 3 days after suspension of the drug." | 7.88 | Pisa syndrome associated with mirtazapine: a case report. ( Hirabayashi, N; Nakagome, K; Okazaki, M; Satake, N; Takano, H; Yamada, M; Yamada, Y, 2018) |
| "A 40-year-old woman with bipolar disorder who was taking mirtazapine presented with mydriasis, abnormal diaphoresis, myoclonus and muscle rigidity after taking metocloplamide." | 7.85 | Metoclopramide-induced Serotonin Syndrome. ( Harada, T; Hirosawa, T; Morinaga, K; Shimizu, T, 2017) |
| " Based on the case report of a patient who developed mania with higher than recommended dosage of mirtazapine, we review the literature on the atypical nature of manic symptoms with mirtazapine." | 5.31 | Dysphoric mania induced by high-dose mirtazapine: a case for 'norepinephrine syndrome'? ( Bhanji, NH; Chouinard, G; Margolese, HC; Saint-Laurent, M, 2002) |
| "The authors report a case involving a 79-year-old woman with bipolar disorder, in whom Pisa syndrome occurred after introduction of mirtazapine, and completely disappeared 3 days after suspension of the drug." | 3.88 | Pisa syndrome associated with mirtazapine: a case report. ( Hirabayashi, N; Nakagome, K; Okazaki, M; Satake, N; Takano, H; Yamada, M; Yamada, Y, 2018) |
| "A 40-year-old woman with bipolar disorder who was taking mirtazapine presented with mydriasis, abnormal diaphoresis, myoclonus and muscle rigidity after taking metocloplamide." | 3.85 | Metoclopramide-induced Serotonin Syndrome. ( Harada, T; Hirosawa, T; Morinaga, K; Shimizu, T, 2017) |
| " We report a case with no previous history of bipolar disorder, whereas developed full-blown psychotic manic symptoms soon after switch from fluoxetine to mirtazapine." | 3.75 | Antidepressant-associated mania: soon after switch from fluoxetine to mirtazapine in an elderly woman with mixed depressive features. ( Liang, KY; Liao, SC; Liu, CC, 2009) |
| "The pharmacologic treatment of schizophrenia and bipolar disorder leaves much to be desired." | 2.48 | Adjunct treatments for schizophrenia and bipolar disorder: what to try when you are out of ideas. ( Davis, JM; Torrey, EF, 2012) |
| "Unipolar depression is also strongly influenced by nongenetic environmental factors (e." | 2.42 | [Genetics of depression. Current knowledge and perspectives]. ( Maier, W, 2004) |
| "Mirtazapine has a specific pharmacodynamics, blocking not only post-synaptic serotonergic receptors but also α2-presynaptic adrenergic receptors." | 1.51 | [Mirtazapine-Induced Mania: A Case Report]. ( Abreu, T; Barranha, R; Freitas, C; Von Doellinger, O, 2019) |
| " Based on the case report of a patient who developed mania with higher than recommended dosage of mirtazapine, we review the literature on the atypical nature of manic symptoms with mirtazapine." | 1.31 | Dysphoric mania induced by high-dose mirtazapine: a case for 'norepinephrine syndrome'? ( Bhanji, NH; Chouinard, G; Margolese, HC; Saint-Laurent, M, 2002) |
| "Mirtazapine is a new antidepressant with a specific pharmacological profile which is different from all other currently available antidepressants." | 1.30 | [Mirtazapine in inpatient treatment of depressed patients]. ( Bailer, U; Kasper, S; Pezawas, L; Praschak-Rieder, N, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (16.00) | 18.2507 |
| 2000's | 12 (48.00) | 29.6817 |
| 2010's | 8 (32.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Freitas, C | 1 |
| Barranha, R | 1 |
| Abreu, T | 1 |
| Von Doellinger, O | 1 |
| Teodoro, T | 1 |
| Harada, T | 1 |
| Hirosawa, T | 1 |
| Morinaga, K | 1 |
| Shimizu, T | 1 |
| Yamada, Y | 1 |
| Takano, H | 1 |
| Yamada, M | 1 |
| Satake, N | 1 |
| Hirabayashi, N | 1 |
| Okazaki, M | 1 |
| Nakagome, K | 1 |
| Lackner, N | 1 |
| Birner, A | 1 |
| Bengesser, SA | 1 |
| Reininghaus, B | 1 |
| Kapfhammer, HP | 1 |
| Reininghaus, E | 1 |
| Liu, CC | 1 |
| Liang, KY | 1 |
| Liao, SC | 1 |
| Benedetti, F | 1 |
| Barbini, B | 1 |
| Bernasconi, A | 1 |
| Fulgosi, MC | 1 |
| Colombo, C | 1 |
| Dallaspezia, S | 1 |
| Gavinelli, C | 1 |
| Marino, E | 1 |
| Pirovano, A | 1 |
| Radaelli, D | 1 |
| Smeraldi, E | 1 |
| Horstmann, S | 1 |
| Dose, T | 1 |
| Lucae, S | 1 |
| Kloiber, S | 1 |
| Menke, A | 1 |
| Hennings, J | 1 |
| Spieler, D | 1 |
| Uhr, M | 1 |
| Holsboer, F | 1 |
| Ising, M | 1 |
| Goyal, N | 1 |
| Sinha, VK | 1 |
| Grønli, O | 1 |
| Stensland, GØ | 1 |
| Wynn, R | 1 |
| Olstad, R | 1 |
| Habermeyer, B | 1 |
| Bayer, U | 1 |
| Müller-Spahn, F | 1 |
| Basavraj, V | 1 |
| Nanjundappa, GB | 1 |
| Chandra, PS | 1 |
| Torrey, EF | 1 |
| Davis, JM | 1 |
| Estabrook, KR | 1 |
| Pheister, M | 1 |
| Bhanji, NH | 1 |
| Margolese, HC | 1 |
| Saint-Laurent, M | 1 |
| Chouinard, G | 1 |
| Maier, W | 1 |
| Wilson, MS | 1 |
| Apikoglu Rabus, S | 1 |
| Izzettin, F | 1 |
| Rabus, M | 1 |
| Bilici, M | 1 |
| Schüle, C | 1 |
| Baghai, TC | 1 |
| Eser, D | 1 |
| Hecht, S | 1 |
| Hermisson, I | 1 |
| Born, C | 1 |
| Häfner, S | 1 |
| Nothdurfter, C | 1 |
| Rupprecht, R | 1 |
| Soutullo, CA | 1 |
| McElroy, SL | 1 |
| Keck, PE | 1 |
| Bailer, U | 1 |
| Praschak-Rieder, N | 1 |
| Pezawas, L | 1 |
| Kasper, S | 1 |
| De León, OA | 1 |
| Furmaga, KM | 1 |
| Kaltsounis, J | 1 |
| MacCall, C | 1 |
| Callender, J | 1 |
| Ng, B | 1 |
| Raja, M | 1 |
| Azzoni, A | 1 |
2 reviews available for mirtazapine and Bipolar Disorder
| Article | Year |
|---|---|
Adjunct treatments for schizophrenia and bipolar disorder: what to try when you are out of ideas.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; An | 2012 |
[Genetics of depression. Current knowledge and perspectives].
Topics: Adolescent; Adult; Age Factors; Aged; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depressive | 2004 |
2 trials available for mirtazapine and Bipolar Disorder
| Article | Year |
|---|---|
Suppressive effect of mirtazapine on the HPA system in acutely depressed women seems to be transient and not related to antidepressant action.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Antidepressive Agents, Tricyclic; Bipolar Disorder; | 2009 |
Mirtazapine monotherapy versus combination therapy with mirtazapine and aripiprazole in depressed patients without psychotic features: a 4-week open-label parallel-group study.
Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Aripiprazole; Bipolar Disorder; | 2007 |
21 other studies available for mirtazapine and Bipolar Disorder
| Article | Year |
|---|---|
[Mirtazapine-Induced Mania: A Case Report].
Topics: Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Humans; Male; Middle Aged; Mirtazapin | 2019 |
Antidepressant Use and the Risk of Mood Instability.
Topics: Antidepressive Agents; Bipolar Disorder; Humans; Mirtazapine | 2020 |
Metoclopramide-induced Serotonin Syndrome.
Topics: Adult; Antiemetics; Bipolar Disorder; Drug Interactions; Female; Humans; Metoclopramide; Mianserin; | 2017 |
Pisa syndrome associated with mirtazapine: a case report.
Topics: Aged; Antidepressive Agents; Bipolar Disorder; Dystonia; Female; Humans; Mirtazapine; Syndrome | 2018 |
[Pediatric bipolar disorder - case report of a bipolar patient with disease onset in childhood and adolescence: implications for diagnosis and therapy].
Topics: Adolescent; Age of Onset; Antipsychotic Agents; Bipolar Disorder; Child; Diagnosis, Differential; Di | 2014 |
Antidepressant-associated mania: soon after switch from fluoxetine to mirtazapine in an elderly woman with mixed depressive features.
Topics: Adrenergic alpha-Antagonists; Aged; Bipolar Disorder; Depressive Disorder, Major; Dose-Response Rela | 2009 |
Serotonin 5-HT2A receptor gene variants influence antidepressant response to repeated total sleep deprivation in bipolar depression.
Topics: Adult; Analysis of Variance; Antidepressive Agents, Tricyclic; Bipolar Disorder; Female; Humans; Mal | 2008 |
Mirtazapine-induced manic switch in adolescent unipolar depression.
Topics: Adolescent; Antidepressive Agents, Tricyclic; Antimanic Agents; Bipolar Disorder; Depressive Disorde | 2008 |
Neurotrophic factors in serum following ECT: a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Bipolar Disorder; Combined Modality Therapy; Cyclohexanols; Depressi | 2009 |
Mania associated with mirtazepine treatment and mixed depression.
Topics: Antidepressive Agents, Tricyclic; Bipolar Disorder; Depression; Humans; Male; Mianserin; Middle Aged | 2010 |
Mirtazapine induced mania in a woman with major depression in the absence of features of bipolarity.
Topics: Adult; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depressive Disorder, Major; Female; Human | 2011 |
A case of quetiapine XR and divalproex-associated neutropenia followed by successful use of ziprasidone.
Topics: Adult; Anti-Anxiety Agents; Antimanic Agents; Antipsychotic Agents; Anxiety Disorders; Bipolar Disor | 2012 |
Dysphoric mania induced by high-dose mirtazapine: a case for 'norepinephrine syndrome'?
Topics: Adult; Antidepressive Agents, Second-Generation; Bipolar Disorder; Depressive Disorder; Dose-Respons | 2002 |
Mirtazapine for akathisia in bipolar disorder.
Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Bipolar Disorder; Female; Humans; Male; Mianse | 2005 |
Severe creatine kinase increase during quetiapine and mirtazapine treatment.
Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Creatine Kinase; Dibenzothiazepines; Drug Therapy, Co | 2006 |
Hypomania associated with mirtazapine augmentation of sertraline.
Topics: 1-Naphthylamine; Ambulatory Care; Antipsychotic Agents; Bipolar Disorder; Depressive Disorder; Drug | 1998 |
[Mirtazapine in inpatient treatment of depressed patients].
Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Bipolar Disorder; Contraindication | 1998 |
Mirtazapine-induced mania in a case of poststroke depression.
Topics: Aged; Antidepressive Agents, Tricyclic; Bipolar Disorder; Cerebrovascular Disorders; Depression; Hum | 1999 |
Mirtazapine withdrawal causing hypomania.
Topics: Aged; Antidepressive Agents, Tricyclic; Bipolar Disorder; Female; Humans; Mianserin; Mirtazapine; Su | 1999 |
Mania associated with mirtazapine augmentation of fluoxetine.
Topics: Adrenergic alpha-Antagonists; Bipolar Disorder; Dose-Response Relationship, Drug; Drug Administratio | 2002 |
Mirtazapine overdose with benign outcome.
Topics: Antidepressive Agents, Tricyclic; Bipolar Disorder; Drug Overdose; Female; Humans; Mianserin; Middle | 2002 |