mirtazapine has been researched along with Angelman Syndrome in 1 studies
Mirtazapine: A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.
Angelman Syndrome: A syndrome characterized by multiple abnormalities, MENTAL RETARDATION, and movement disorders. Present usually are skull and other abnormalities, frequent infantile spasms (SPASMS, INFANTILE); easily provoked and prolonged paroxysms of laughter (hence happy); jerky puppetlike movements (hence puppet); continuous tongue protrusion; motor retardation; ATAXIA; MUSCLE HYPOTONIA; and a peculiar facies. It is associated with maternal deletions of chromosome 15q11-13 and other genetic abnormalities. (From Am J Med Genet 1998 Dec 4;80(4):385-90; Hum Mol Genet 1999 Jan;8(1):129-35)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Medical records of individuals seen in the Comprehensive Angelman Syndrome clinic were retrospectively reviewed to determine the use of mirtazapine for disordered sleep." | 7.96 | Mirtazapine for sleep disturbances in Angelman syndrome: a retrospective chart review of 8 pediatric cases. ( Carson, R; Duis, J; Hanzlik, E; Klinger, SA, 2020) |
| " Medical records of individuals seen in the Comprehensive Angelman Syndrome clinic were retrospectively reviewed to determine the use of mirtazapine for disordered sleep." | 3.96 | Mirtazapine for sleep disturbances in Angelman syndrome: a retrospective chart review of 8 pediatric cases. ( Carson, R; Duis, J; Hanzlik, E; Klinger, SA, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hanzlik, E | 1 |
| Klinger, SA | 1 |
| Carson, R | 1 |
| Duis, J | 1 |
1 other study available for mirtazapine and Angelman Syndrome
| Article | Year |
|---|---|
Mirtazapine for sleep disturbances in Angelman syndrome: a retrospective chart review of 8 pediatric cases.
Topics: Adolescent; Angelman Syndrome; Child; Child, Preschool; Humans; Mirtazapine; Retrospective Studies; | 2020 |