Page last updated: 2024-10-31

mirtazapine and Allodynia

mirtazapine has been researched along with Allodynia in 6 studies

Mirtazapine: A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.

Research Excerpts

ExcerptRelevanceReference
" The present study was designed to explore the effects and most appropriate dosage of mirtazapine in treating neuropathic pain and its possible neuroimmune mechanisms."5.35Repeated administration of mirtazapine inhibits development of hyperalgesia/allodynia and activation of NF-kappaB in a rat model of neuropathic pain. ( Feng, X; Hu, Y; Song, J; Wei, X; Xu, J; Zhu, J, 2008)
"Mirtazapine (MTZ) is an antidepressant, which is considered to enhance noradrenergic and serotonergic neurotransmission via antagonistic action at central α2-adrenergic autoreceptors and heteroreceptors."1.38Effects of mirtazapine on sleep disturbance under neuropathic pain-like state. ( Enomoto, T; Hirayama, S; Horiuchi, H; Ikegami, D; Inada, E; Iseki, M; Nagase, H; Nakahara, K; Narita, M; Sakai, H; Suzuki, T; Torigoe, K; Yamashita, A; Yanase, M, 2012)
" All substances were dosed between 0."1.35Racemic intrathecal mirtazapine but not its enantiomers acts anti-neuropathic after chronic constriction injury in rats. ( Driehsen, C; Freynhagen, R; Hermanns, H; Lipfert, P; Muth-Selbach, U, 2009)
"Mirtazapine was orally administered to rats that had been operated on daily for 14 days."1.35Interaction of glia activation and neurotransmission in hippocampus of neuropathic rats treated with mirtazapine. ( Hu, Y; Liu, J; Wei, X; Xu, J; Zhu, J, 2009)
" The present study was designed to explore the effects and most appropriate dosage of mirtazapine in treating neuropathic pain and its possible neuroimmune mechanisms."1.35Repeated administration of mirtazapine inhibits development of hyperalgesia/allodynia and activation of NF-kappaB in a rat model of neuropathic pain. ( Feng, X; Hu, Y; Song, J; Wei, X; Xu, J; Zhu, J, 2008)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bektur, E1
Şahin, E1
Ceyhan, E1
Donmez, DB1
Canbek, M1
Baycu, C1
Can, OD1
Liu, X1
Zhang, G1
Dong, L1
Wang, X1
Sun, H1
Shen, J1
Li, W1
Xu, J3
Muth-Selbach, U1
Hermanns, H1
Driehsen, C1
Lipfert, P1
Freynhagen, R1
Zhu, J2
Wei, X2
Liu, J1
Hu, Y2
Enomoto, T1
Yamashita, A1
Torigoe, K1
Horiuchi, H1
Hirayama, S1
Nakahara, K1
Yanase, M1
Sakai, H1
Ikegami, D1
Nagase, H1
Suzuki, T1
Iseki, M1
Inada, E1
Narita, M1
Feng, X1
Song, J1

Other Studies

6 other studies available for mirtazapine and Allodynia

ArticleYear
Beneficial effect of mirtazapine on diabetes-induced hyperalgesia: involvement of TRPV1 and ASIC1 channels in the spinal cord and dorsal root ganglion.
    Neurological research, 2019, Volume: 41, Issue:6

    Topics: Acid Sensing Ion Channels; Animals; Capsaicin; Diabetes Mellitus, Experimental; Disease Models, Anim

2019
Repeated administration of mirtazapine attenuates oxaliplatin-induced mechanical allodynia and spinal NR2B up-regulation in rats.
    Neurochemical research, 2013, Volume: 38, Issue:9

    Topics: Animals; Antidepressive Agents, Tricyclic; Hyperalgesia; Mianserin; Mirtazapine; Organoplatinum Comp

2013
Racemic intrathecal mirtazapine but not its enantiomers acts anti-neuropathic after chronic constriction injury in rats.
    Brain research bulletin, 2009, Apr-06, Volume: 79, Issue:1

    Topics: Analgesics; Animals; Antidepressive Agents; Hot Temperature; Hyperalgesia; Injections, Spinal; Male;

2009
Interaction of glia activation and neurotransmission in hippocampus of neuropathic rats treated with mirtazapine.
    Experimental and clinical psychopharmacology, 2009, Volume: 17, Issue:3

    Topics: Analgesics; Animals; Antidepressive Agents, Tricyclic; Astrocytes; Glial Fibrillary Acidic Protein;

2009
Effects of mirtazapine on sleep disturbance under neuropathic pain-like state.
    Synapse (New York, N.Y.), 2012, Volume: 66, Issue:6

    Topics: Animals; Disease Models, Animal; Histamine H1 Antagonists; Hyperalgesia; Male; Mianserin; Mice; Mice

2012
Repeated administration of mirtazapine inhibits development of hyperalgesia/allodynia and activation of NF-kappaB in a rat model of neuropathic pain.
    Neuroscience letters, 2008, Mar-05, Volume: 433, Issue:1

    Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Cytokines; Denervation; Disease Models, Animal; Do

2008