mirogabalin and Fibromyalgia

mirogabalin has been researched along with Fibromyalgia* in 4 studies

Reviews

1 review(s) available for mirogabalin and Fibromyalgia

Article	Year
The mirogabalin ALDAY phase 3 program in pain associated with fibromyalgia: the lessons learned. Current medical research and opinion, 2020, Volume: 36, Issue:4 Topics: Bridged Bicyclo Compounds; Clinical Trials, Phase III as Topic; Double-Blind Method; Fibromyalgia; Gabapentin; Humans; Neuralgia	2020

Trials

1 trial(s) available for mirogabalin and Fibromyalgia

Article	Year
Efficacy and safety of mirogabalin for the treatment of fibromyalgia: results from three 13-week randomized, double-blind, placebo- and active-controlled, parallel-group studies and a 52-week open-label extension study. Current medical research and opinion, 2019, Volume: 35, Issue:10 Topics: Adult; Bridged Bicyclo Compounds; Double-Blind Method; Female; Fibromyalgia; Humans; Male; Middle Aged; Pregabalin	2019

Article

Year

Efficacy and safety of mirogabalin for the treatment of fibromyalgia: results from three 13-week randomized, double-blind, placebo- and active-controlled, parallel-group studies and a 52-week open-label extension study.

Current medical research and opinion, 2019, Volume: 35, Issue:10

Topics: Adult; Bridged Bicyclo Compounds; Double-Blind Method; Female; Fibromyalgia; Humans; Male; Middle Aged; Pregabalin

2019

Other Studies

2 other study(ies) available for mirogabalin and Fibromyalgia

Article	Year
Mirogabalin, a novel ligand for α Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 139 Topics: Animals; Avoidance Learning; Bridged Bicyclo Compounds; Calcium Channels; Calcium Channels, L-Type; Cognition Disorders; Fibromyalgia; Injections, Intramuscular; Male; Maze Learning; Muscle, Skeletal; Physical Stimulation; Rats; Recognition, Psychology; Saline Solution	2021
Anxiolytic-like effects of mirogabalin, a novel ligand for α Pharmacological reports : PR, 2020, Volume: 72, Issue:3 Mental disorders including anxiety and depression are common comorbidities in fibromyalgia patients, and exert a profound impact on their quality of life. Mirogabalin, a novel ligand for the α. Male Sprague-Dawley rats received two intramuscular injections of acidic saline (pH 4.0) into the gastrocnemius muscle. After the development of tactile allodynia demonstrated by decreased paw withdrawal threshold to von Frey filaments, anxiety-like behaviours were evaluated using the open field test and the elevated plus maze test.. Sluka model rats exhibited anxiety-like behaviours in the open field test (significant decreases in distance travelled and time spent in the central area, and significant increases in time spent in the wall area) and the elevated plus maze test (significant decreases in time spent in the open arms and significant increases in time spent in the closed arms). A single oral dose of mirogabalin (3 or 10 mg/kg) significantly alleviated and normalised these anxiety-like behaviours.. Sluka model rats exhibited anxiety-like behaviours in the open field test and the elevated plus maze test, but mirogabalin alleviated these behaviours. Mirogabalin might thus have the potential to relieve anxiety in fibromyalgia patients. Topics: Animals; Anti-Anxiety Agents; Anxiety; Bridged Bicyclo Compounds; Calcium Channels, L-Type; Elevated Plus Maze Test; Fibromyalgia; Male; Neuralgia; Open Field Test; Pain Threshold; Rats; Rats, Sprague-Dawley	2020

Article

Year

Mirogabalin, a novel ligand for α

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 139

Topics: Animals; Avoidance Learning; Bridged Bicyclo Compounds; Calcium Channels; Calcium Channels, L-Type; Cognition Disorders; Fibromyalgia; Injections, Intramuscular; Male; Maze Learning; Muscle, Skeletal; Physical Stimulation; Rats; Recognition, Psychology; Saline Solution

2021

Anxiolytic-like effects of mirogabalin, a novel ligand for α

Pharmacological reports : PR, 2020, Volume: 72, Issue:3

Mental disorders including anxiety and depression are common comorbidities in fibromyalgia patients, and exert a profound impact on their quality of life. Mirogabalin, a novel ligand for the α. Male Sprague-Dawley rats received two intramuscular injections of acidic saline (pH 4.0) into the gastrocnemius muscle. After the development of tactile allodynia demonstrated by decreased paw withdrawal threshold to von Frey filaments, anxiety-like behaviours were evaluated using the open field test and the elevated plus maze test.. Sluka model rats exhibited anxiety-like behaviours in the open field test (significant decreases in distance travelled and time spent in the central area, and significant increases in time spent in the wall area) and the elevated plus maze test (significant decreases in time spent in the open arms and significant increases in time spent in the closed arms). A single oral dose of mirogabalin (3 or 10 mg/kg) significantly alleviated and normalised these anxiety-like behaviours.. Sluka model rats exhibited anxiety-like behaviours in the open field test and the elevated plus maze test, but mirogabalin alleviated these behaviours. Mirogabalin might thus have the potential to relieve anxiety in fibromyalgia patients.

Topics: Animals; Anti-Anxiety Agents; Anxiety; Bridged Bicyclo Compounds; Calcium Channels, L-Type; Elevated Plus Maze Test; Fibromyalgia; Male; Neuralgia; Open Field Test; Pain Threshold; Rats; Rats, Sprague-Dawley

2020