minoxidil has been researched along with Stevens-Johnson Syndrome in 2 studies
Minoxidil: A potent direct-acting peripheral vasodilator (VASODILATOR AGENTS) that reduces peripheral resistance and produces a fall in BLOOD PRESSURE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p371)
minoxidil : A pyrimidine N-oxide that is pyrimidine-2,4-diamine 3-oxide substituted by a piperidin-1-yl group at position 6.
Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Minoxidil is a direct-acting peripheral vasodilator for the treatment of symptomatic hypertension, or refractory hypertension associated with target organ damage, that is not manageable with a diuretic and two other antihypertensive drugs." | 1.35 | Fatal toxic epidermal necrolysis associated with minoxidil. ( Chahine-Chakhtoura, C; Karaoui, LR, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Karaoui, LR | 1 |
| Chahine-Chakhtoura, C | 1 |
| DiSantis, DJ | 1 |
| Flanagan, J | 1 |
2 other studies available for minoxidil and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
Fatal toxic epidermal necrolysis associated with minoxidil.
Topics: Aged; Antihypertensive Agents; Fatal Outcome; Female; Humans; Minoxidil; Stevens-Johnson Syndrome; V | 2009 |
Minoxidil-induced Stevens-Johnson syndrome.
Topics: Adult; Drug Hypersensitivity; Humans; Male; Minoxidil; Pyrimidines; Stevens-Johnson Syndrome | 1981 |