minoxidil has been researched along with Pulmonary Fibrosis in 2 studies
Minoxidil: A potent direct-acting peripheral vasodilator (VASODILATOR AGENTS) that reduces peripheral resistance and produces a fall in BLOOD PRESSURE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p371)
minoxidil : A pyrimidine N-oxide that is pyrimidine-2,4-diamine 3-oxide substituted by a piperidin-1-yl group at position 6.
Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Minoxidil is an FDA-approved anti-hypertensive agent that inhibits LH that reduces fibrosis." | 5.48 | Lysyl Hydroxylase Inhibition by Minoxidil Blocks Collagen Deposition and Prevents Pulmonary Fibrosis via TGF-β₁/Smad3 Signaling Pathway. ( Duan, L; Fang, H; Guo, B; Liu, W; Rao, S; Shao, S; Zhang, X, 2018) |
| "Minoxidil is an FDA-approved anti-hypertensive agent that inhibits LH that reduces fibrosis." | 1.48 | Lysyl Hydroxylase Inhibition by Minoxidil Blocks Collagen Deposition and Prevents Pulmonary Fibrosis via TGF-β₁/Smad3 Signaling Pathway. ( Duan, L; Fang, H; Guo, B; Liu, W; Rao, S; Shao, S; Zhang, X, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shao, S | 1 |
| Zhang, X | 2 |
| Duan, L | 1 |
| Fang, H | 1 |
| Rao, S | 1 |
| Liu, W | 1 |
| Guo, B | 1 |
| Last, JA | 1 |
| Gerriets, JE | 1 |
| Armstrong, LC | 1 |
| Gelzleichter, TR | 1 |
| Reiser, KM | 1 |
2 other studies available for minoxidil and Pulmonary Fibrosis
| Article | Year |
|---|---|
Lysyl Hydroxylase Inhibition by Minoxidil Blocks Collagen Deposition and Prevents Pulmonary Fibrosis via TGF-β₁/Smad3 Signaling Pathway.
Topics: Animals; Bleomycin; China; Collagen; Extracellular Matrix; Fibroblasts; Fibrosis; Humans; Idiopathic | 2018 |
Hydroxylation of collagen by lungs of rats administered bleomycin.
Topics: Animals; Bleomycin; Collagen; Dose-Response Relationship, Drug; Hydroxylation; Hydroxylysine; Lung; | 1990 |