minoxidil has been researched along with Necrosis in 10 studies
Minoxidil: A potent direct-acting peripheral vasodilator (VASODILATOR AGENTS) that reduces peripheral resistance and produces a fall in BLOOD PRESSURE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p371)
minoxidil : A pyrimidine N-oxide that is pyrimidine-2,4-diamine 3-oxide substituted by a piperidin-1-yl group at position 6.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Minoxidil and other potent vasodilators cause coronary arterial injury, right atrial hemorrhagic lesions, and subendocardial necrosis in dogs." | 3.67 | Pathogenesis of cardiovascular alterations in dogs treated with minoxidil. ( Carlson, RG; DuCharme, DW; Humphrey, SJ; Mesfin, GM; Piper, RC; Zins, GR, 1989) |
| "Previous studies have shown that oral administration of minoxidil on 2 consecutive days produces an increase in heart rate and myocardial necrosis in Beagle dogs." | 3.66 | Divergent effects of propranolol and furosemide pretreatment on acute cardiomyopathy induced by minoxidil in beagle dogs. ( Balazs, T; Ferrans, VJ; Herman, EH; Young, RS, 1981) |
| "The treatment with minoxidil induced myocardial necrosis, coronary arteriopathy and degeneration of renal tubules in animals treated with 150 mg/kg or 200 mg/kg." | 1.35 | Cardiovascular toxicity of minoxidil in the marmoset. ( Bonnet, P; Daguès, N; Eder, V; Hanton, G; Rochefort, GY; Sobry, C, 2008) |
| "Necrosis was evident in the differentiating epithelial elements forming the cuticle, cortex, and inner root sheath." | 1.28 | Minoxidil stimulates mouse vibrissae follicles in organ culture. ( Buhl, AE; Holland, JM; Kawabe, TT; Waldon, DJ, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Freiha, M | 1 |
| Achim, M | 1 |
| Gheban, BA | 1 |
| Moldovan, R | 1 |
| Filip, GA | 1 |
| Yang, Q | 1 |
| Qiu, L | 1 |
| Yi, C | 1 |
| Xue, P | 1 |
| Yu, Z | 1 |
| Ma, X | 1 |
| Su, Y | 1 |
| Guo, S | 1 |
| Hanton, G | 2 |
| Sobry, C | 1 |
| Daguès, N | 1 |
| Rochefort, GY | 1 |
| Bonnet, P | 1 |
| Eder, V | 1 |
| Herman, EH | 3 |
| Balazs, T | 2 |
| Ferrans, VJ | 3 |
| Young, RS | 1 |
| Zhang, J | 1 |
| Chadwick, DP | 1 |
| Young, R | 1 |
| Earl, FL | 1 |
| Krop, S | 1 |
| Dogterom, P | 1 |
| Zbinden, G | 1 |
| Reznik, GK | 1 |
| Longeart, L | 1 |
| Lodola, A | 1 |
| Buhl, AE | 1 |
| Waldon, DJ | 1 |
| Kawabe, TT | 1 |
| Holland, JM | 1 |
| Mesfin, GM | 1 |
| Piper, RC | 1 |
| DuCharme, DW | 1 |
| Carlson, RG | 1 |
| Humphrey, SJ | 1 |
| Zins, GR | 1 |
1 review available for minoxidil and Necrosis
| Article | Year |
|---|---|
Cardiotoxicity of vasodilators and positive inotropic/vasodilating drugs in dogs: an overview.
Topics: Amines; Animals; Animals, Laboratory; Coronary Disease; Dogs; Humans; Minoxidil; Myocardium; Necrosi | 1992 |
9 other studies available for minoxidil and Necrosis
| Article | Year |
|---|---|
In Vivo Study of the Effects of Propranolol, Timolol, and Minoxidil on Burn Wound Healing in Wistar Rats.
Topics: Animals; Antioxidants; Burns; Female; Fibrosis; Inflammation; Minoxidil; Necrosis; Propranolol; Rats | 2023 |
Reversible Alopecia with Localized Scalp Necrosis After Accidental Embolization of the Parietal Artery with Hyaluronic Acid.
Topics: Adult; Alopecia; Arterial Occlusive Diseases; Arteries; Biopsy, Needle; Cosmetic Techniques; Dermal | 2017 |
Cardiovascular toxicity of minoxidil in the marmoset.
Topics: Animals; Blood Chemical Analysis; Callithrix; Cardiovascular Diseases; Cyclic Nucleotide Phosphodies | 2008 |
Divergent effects of propranolol and furosemide pretreatment on acute cardiomyopathy induced by minoxidil in beagle dogs.
Topics: Animals; Dogs; Drug Interactions; Furosemide; Heart Diseases; Heart Rate; Hydrochlorothiazide; Male; | 1981 |
Age dependence of the cardiac lesions induced by minoxidil in the rat.
Topics: Aging; Animals; Arterioles; Arteritis; Blood Pressure; Dose-Response Relationship, Drug; Heart; Hear | 1996 |
Acute cardiomyopathy induced by the vasodilating antihypertensive agent minoxidil.
Topics: Anesthesia; Animals; Arteritis; Cardiomyopathies; Coronary Vessels; Dogs; Hemorrhage; Hypotension; M | 1979 |
Cardiotoxicity of hydralazine and minoxidil in the rat. Influence of age.
Topics: Aging; Animals; Blood Pressure; Heart Diseases; Heart Rate; Hydralazine; Isoproterenol; Minoxidil; M | 1991 |
Minoxidil stimulates mouse vibrissae follicles in organ culture.
Topics: Animals; Cell Differentiation; Cysteine; Epidermis; Glycine; Keratins; Mice; Minoxidil; Necrosis; Or | 1989 |
Pathogenesis of cardiovascular alterations in dogs treated with minoxidil.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Cardiovascular Diseases; Carotid Sinus; Corona | 1989 |