minoxidil has been researched along with Myocardial Ischemia in 2 studies
Minoxidil: A potent direct-acting peripheral vasodilator (VASODILATOR AGENTS) that reduces peripheral resistance and produces a fall in BLOOD PRESSURE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p371)
minoxidil : A pyrimidine N-oxide that is pyrimidine-2,4-diamine 3-oxide substituted by a piperidin-1-yl group at position 6.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| " This conclusion is strengthened by the observation that hypertrophic hearts from volume-overloaded rats had similar amounts of cardiac hypertrophy to the hearts from the hypertensive rats, without a change in flow, coronary vascular resistance or ischaemic sensitivity, whereas the hearts from isoproterenol-treated rats had lower ischaemic sensitivity and coronary vascular resistance." | 3.69 | Sensitivity to ischaemic ATP breakdown in different models of cardiac hypertrophy in rats. ( Harmsen, E; Leenen, FH; Ruzicka, M; Schoemaker, R; Yu, J, 1994) |
| "Pretreatment with minoxidil significantly enhanced the recovery of myocardial contraction during reperfusion after ischemia." | 1.31 | Effects of minoxidil on ischemia-induced mechanical and metabolic dysfunction in dog myocardium. ( Ichihara, K; Ichinosawa, K; Kaneta, S; Kano, S; Satoh, K; Yamamoto, A, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yamamoto, A | 1 |
| Satoh, K | 1 |
| Ichinosawa, K | 1 |
| Kaneta, S | 1 |
| Kano, S | 1 |
| Ichihara, K | 1 |
| Harmsen, E | 1 |
| Schoemaker, R | 1 |
| Yu, J | 1 |
| Ruzicka, M | 1 |
| Leenen, FH | 1 |
2 other studies available for minoxidil and Myocardial Ischemia
| Article | Year |
|---|---|
Effects of minoxidil on ischemia-induced mechanical and metabolic dysfunction in dog myocardium.
Topics: Adenosine Triphosphate; Animals; Antihypertensive Agents; Dimethyl Sulfoxide; Dogs; Female; Injectio | 2002 |
Sensitivity to ischaemic ATP breakdown in different models of cardiac hypertrophy in rats.
Topics: Adenosine Triphosphate; Animals; Cardiomegaly; Coronary Circulation; Hyperemia; Hypertension; Isopro | 1994 |