minoxidil has been researched along with Hypotension in 18 studies
Minoxidil: A potent direct-acting peripheral vasodilator (VASODILATOR AGENTS) that reduces peripheral resistance and produces a fall in BLOOD PRESSURE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p371)
minoxidil : A pyrimidine N-oxide that is pyrimidine-2,4-diamine 3-oxide substituted by a piperidin-1-yl group at position 6.
Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We report a case of ingestion of topical minoxidil [Rogaine® (Johnson & Johnson Healthcare Products, Division of McNeil-PPC, Inc)] resulting in refractory hypotension that was successfully managed with the oral α (1) agonist midodrine." | 7.77 | Refractory hypotension due to Rogaine® (minoxidil) ingestion managed with midodrine. ( Aaronson, P; Garrard, A; Sollee, D; Wood, A, 2011) |
| "Severe prolonged hypotension developed in a hypertensive patient several hours after the initial doses of minoxidil therapy." | 7.67 | Prolonged hypotension after initial minoxidil dose. ( Allon, M; Hall, WD; Macon, EJ, 1986) |
| "Propranolol was demonstrated to block hydralazine-induced increases in serum renin activity in genetically hypertensive rats." | 5.25 | Altered renin release and propranolol potentiation of vasodilatory drug hypotension. ( Keeton, K; Pettinger, WA, 1975) |
| " We report a case of ingestion of topical minoxidil [Rogaine® (Johnson & Johnson Healthcare Products, Division of McNeil-PPC, Inc)] resulting in refractory hypotension that was successfully managed with the oral α (1) agonist midodrine." | 3.77 | Refractory hypotension due to Rogaine® (minoxidil) ingestion managed with midodrine. ( Aaronson, P; Garrard, A; Sollee, D; Wood, A, 2011) |
| " Toxicity manifested as profound hypotension, requiring vasopressor support, intubation, prolonged tachycardia, and fluid overload with pleural effusions, requiring several days of therapy with furosemide." | 3.70 | Overdose of Rogaine Extra Strength for Men topical minoxidil preparation. ( Epstein, SK; Farrell, SE, 1999) |
| "Severe prolonged hypotension developed in a hypertensive patient several hours after the initial doses of minoxidil therapy." | 3.67 | Prolonged hypotension after initial minoxidil dose. ( Allon, M; Hall, WD; Macon, EJ, 1986) |
| " Papaverine (10 mg/kg) caused hypotension and increased PRA." | 3.66 | Renin response to hemorrhage and hypotension in the aglomerular toadfish Opsanus tau. ( Lunde, LG; Nishimura, H; Zucker, A, 1979) |
| "Minoxidil is a strong vasodilator used first in the 1970s for severe hypertension." | 1.37 | [Minoxidil intoxication, the pharmacological agent of a hair lotion]. ( Aprahamian, A; Chéron, G; Escoda, S; Merckx, A; Patteau, G, 2011) |
| "Hypotension was produced by intravenous infusion of the vasodilator drug minoxidil (25 microg x kg(-1) x min(-1)) concurrently with the angiotensin-converting enzyme inhibitor captopril (0." | 1.31 | Effects of hypotension and fluid depletion on central angiotensin-induced thirst and salt appetite. ( Johnson, AK; Thunhorst, RL, 2001) |
| "Minoxidil-treated pigs had tachycardia and hypotension and were killed 24 hr after the second dose." | 1.27 | Cardiac morphologic alterations in acute minoxidil cardiotoxicity in miniature swine. ( Ferrans, VJ; Herman, EH; Van Vleet, JF, 1984) |
| "Propranolol was demonstrated to block hydralazine-induced increases in serum renin activity in genetically hypertensive rats." | 1.25 | Altered renin release and propranolol potentiation of vasodilatory drug hypotension. ( Keeton, K; Pettinger, WA, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (44.44) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 4 (22.22) | 24.3611 |
| 2020's | 3 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Arun Babu, T | 2 |
| Vijayasankar, V | 2 |
| Varman, N | 2 |
| Chakar, B | 1 |
| Salter, M | 1 |
| Roberts, DM | 1 |
| Asada, M | 1 |
| Okazaki, Y | 1 |
| Ichiba, T | 1 |
| Naito, H | 1 |
| Namera, A | 1 |
| Jordan, TJM | 1 |
| Yaxley, PE | 1 |
| Culler, CA | 1 |
| Balakrishnan, A | 1 |
| Claudet, I | 1 |
| Cortey, C | 1 |
| Honorat, R | 1 |
| Franchitto, N | 1 |
| Thunhorst, RL | 2 |
| Beltz, TG | 1 |
| Johnson, AK | 2 |
| Aprahamian, A | 1 |
| Escoda, S | 1 |
| Patteau, G | 1 |
| Merckx, A | 1 |
| Chéron, G | 1 |
| Garrard, A | 1 |
| Wood, A | 1 |
| Sollee, D | 1 |
| Aaronson, P | 1 |
| Van Vleet, JF | 1 |
| Herman, EH | 2 |
| Ferrans, VJ | 2 |
| Baum, T | 1 |
| Sabin, C | 1 |
| Moran, RM | 1 |
| Farrell, SE | 1 |
| Epstein, SK | 1 |
| Pettinger, WA | 1 |
| Keeton, K | 1 |
| Balazs, T | 1 |
| Young, R | 1 |
| Earl, FL | 1 |
| Krop, S | 1 |
| Nishimura, H | 1 |
| Lunde, LG | 1 |
| Zucker, A | 1 |
| Haeusler, G | 1 |
| Gerold, M | 1 |
| McCormick, MA | 1 |
| Forman, MH | 1 |
| Manoguerra, AS | 1 |
| Allon, M | 1 |
| Hall, WD | 1 |
| Macon, EJ | 1 |
18 other studies available for minoxidil and Hypotension
| Article | Year |
|---|---|
Minoxidil Ingestion in a Toddler.
Topics: Humans; Hypotension; Minoxidil; Vasodilator Agents | 2022 |
Minoxidil Ingestion in a Toddler.
Topics: Humans; Hypotension; Minoxidil; Vasodilator Agents | 2022 |
Minoxidil Ingestion in a Toddler.
Topics: Humans; Hypotension; Minoxidil; Vasodilator Agents | 2022 |
Minoxidil Ingestion in a Toddler.
Topics: Humans; Hypotension; Minoxidil; Vasodilator Agents | 2022 |
Minoxidil overdose with hypotension effectively managed with norepinephrine, rather than dopamine.
Topics: Dopamine; Drug Overdose; Humans; Hypotension; Minoxidil; Norepinephrine; Vasodilator Agents | 2023 |
Unexpected refractory hypotension following intradermal minoxidil injection.
Topics: Blood Pressure; Heart Rate; Humans; Hypertension; Hypotension; Minoxidil | 2023 |
Successful management of minoxidil toxicosis in a dog.
Topics: Animals; Dog Diseases; Dogs; Dopamine; Emulsions; Heart Rate; Hypotension; Minoxidil; Phospholipids; | 2018 |
Minoxidil topical solution: an unsafe product for children.
Topics: Administration, Topical; Antihypertensive Agents; Blood Pressure; Child; Electrocardiography; Female | 2015 |
Hypotension- and osmotically induced thirst in old Brown Norway rats.
Topics: Age Factors; Aging; Animals; Blood Pressure; Dehydration; Disease Models, Animal; Diuresis; Drinking | 2009 |
[Minoxidil intoxication, the pharmacological agent of a hair lotion].
Topics: Child, Preschool; Female; Hair Preparations; Humans; Hypotension; Minoxidil; Monitoring, Physiologic | 2011 |
Refractory hypotension due to Rogaine® (minoxidil) ingestion managed with midodrine.
Topics: Administration, Oral; Adrenergic alpha-1 Receptor Agonists; Blood Pressure; Emergency Service, Hospi | 2011 |
Cardiac morphologic alterations in acute minoxidil cardiotoxicity in miniature swine.
Topics: Animals; Arterioles; Coronary Vessels; Dogs; Endothelium; Heart Atria; Heart Diseases; Hemorrhage; H | 1984 |
Comparison of hypotensive, orthostatic and sympathetic inhibitory actions of antihypertensive drugs in rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Diazepam; Guanethidine; Heart Rate; Hyd | 1981 |
Overdose of Rogaine Extra Strength for Men topical minoxidil preparation.
Topics: Administration, Oral; Adult; Drug Overdose; Female; Furosemide; Humans; Hypotension; Minoxidil; Nonp | 1999 |
Effects of hypotension and fluid depletion on central angiotensin-induced thirst and salt appetite.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Appetite; Blood Pressure; Dehydration; Diuretics; | 2001 |
Altered renin release and propranolol potentiation of vasodilatory drug hypotension.
Topics: Angiotensin II; Animals; Blood Pressure; Central Nervous System; Depression, Chemical; Dose-Response | 1975 |
Acute cardiomyopathy induced by the vasodilating antihypertensive agent minoxidil.
Topics: Anesthesia; Animals; Arteritis; Cardiomyopathies; Coronary Vessels; Dogs; Hemorrhage; Hypotension; M | 1979 |
Renin response to hemorrhage and hypotension in the aglomerular toadfish Opsanus tau.
Topics: Angiotensinogen; Animals; Female; Fishes; Hematocrit; Hemorrhage; Hypotension; Male; Minoxidil; Papa | 1979 |
Increased levels of prostaglandin-like material in the canine blood during arterial hypotension produced by hydralazine, dihydralazine and minoxidil.
Topics: Angiotensin II; Animals; Blood Pressure; Dihydralazine; Dogs; Female; Guinea Pigs; Hydralazine; Hypo | 1979 |
Severe toxicity from ingestion of a topical minoxidil preparation.
Topics: Administration, Oral; Adult; Dopamine; Fluid Therapy; Hemodynamics; Humans; Hypotension; Male; Minox | 1989 |
Prolonged hypotension after initial minoxidil dose.
Topics: Cardiac Output; Female; Humans; Hypertension; Hypotension; Middle Aged; Minoxidil; Time Factors; Vas | 1986 |