Page last updated: 2024-10-31

minoxidil and Hypertension, Renal

minoxidil has been researched along with Hypertension, Renal in 28 studies

Minoxidil: A potent direct-acting peripheral vasodilator (VASODILATOR AGENTS) that reduces peripheral resistance and produces a fall in BLOOD PRESSURE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p371)
minoxidil : A pyrimidine N-oxide that is pyrimidine-2,4-diamine 3-oxide substituted by a piperidin-1-yl group at position 6.

Hypertension, Renal: Persistent high BLOOD PRESSURE due to KIDNEY DISEASES, such as those involving the renal parenchyma, the renal vasculature, or tumors that secrete RENIN.

Research Excerpts

ExcerptRelevanceReference
"The antihypertensive efficacy of minoxidil and captopril was compared in 23 males with essential or renal parenchymatous hypertension refractory to conventional antihypertensive drug therapy."9.06Minoxidil and captopril in severe hypertension. ( Baumgart, P; Foerster, E; Greminger, P; Vetter, H; Vetter, W, 1986)
"In 16 fo 20 patients with treatment-resistant hypertension endralazine, combined with beta-receptor blockers and diuretics, significantly lowered mean arterial blood pressure from 198/112 mmHg to 148/88 mmHg."9.05[Management of treatment-resistant hypertension: comparison of the antihypertensive effect of endralazine and minoxidil (author's transl)]. ( Glöckner, WM; Kindler, J; Konrads, A; Meurer, KA; Schulz, V; Sieberth, HG; Vaith, P, 1981)
"The effect of the new vasodilator, minoxidil, on blood pressure and plasma renin activity was studied in 21 hypertensive patients: 12 patients with essential and 9 with renal hypertension."9.04The effect of minoxidil on blood pressure and plasma renin activity in patients with essential and renal hypertension. ( Werning, C, 1976)
"The objective of the present study was to retrospectively examine whether the addition of minoxidil to patients who were already treated with maximum doses of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers but who had not achieved target blood pressures, has any detrimental effect on proteinuria or renal function or whether its effect on blood pressure prove salutary."7.73Does the hyperfiltration of minoxidil result in increased proteinuria and loss of renoprotection conferred by angiotensin inhibition? ( Carter, TB; Dansby, LM; Diskin, CJ; Radcliff, L; Stokes, TJ, 2006)
"Sixty-nine patients with refractory hypertension were treated with minoxidil and in 66 good control of blood pressure was achieved."7.66Improvement of renal function during long-term treatment of severe hypertension with minoxidil. ( Bing, RF; Heagerty, A; Pohl, JE; Russell, GI; Swales, JD; Taverner, D; Thurston, H, 1983)
"7 years) with severe essential hypertension (n = 21) and renovascular hypertension (n = 1) were treated with a mean daily dosage of 16."5.26[Minoxidil in treatment resistant hypertension]. ( Furrer, J; Nussberger, J; Reuteler, H; Siegenthaler, W; Studer, A; Tenschert, W; Vetter, W, 1979)
"Minoxidil is a new, effective, investigational antihypertensive drug."5.26Minoxidil-induced hypertrichosis: treatment with calcium thioglycolate depilatory. ( Aeling, JL; Ball, J; Earhart, RN; Nuss, DD, 1977)
"The antihypertensive efficacy of minoxidil and captopril was compared in 23 males with essential or renal parenchymatous hypertension refractory to conventional antihypertensive drug therapy."5.06Minoxidil and captopril in severe hypertension. ( Baumgart, P; Foerster, E; Greminger, P; Vetter, H; Vetter, W, 1986)
"In 16 fo 20 patients with treatment-resistant hypertension endralazine, combined with beta-receptor blockers and diuretics, significantly lowered mean arterial blood pressure from 198/112 mmHg to 148/88 mmHg."5.05[Management of treatment-resistant hypertension: comparison of the antihypertensive effect of endralazine and minoxidil (author's transl)]. ( Glöckner, WM; Kindler, J; Konrads, A; Meurer, KA; Schulz, V; Sieberth, HG; Vaith, P, 1981)
"The effect of the new vasodilator, minoxidil, on blood pressure and plasma renin activity was studied in 21 hypertensive patients: 12 patients with essential and 9 with renal hypertension."5.04The effect of minoxidil on blood pressure and plasma renin activity in patients with essential and renal hypertension. ( Werning, C, 1976)
"The objective of the present study was to retrospectively examine whether the addition of minoxidil to patients who were already treated with maximum doses of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers but who had not achieved target blood pressures, has any detrimental effect on proteinuria or renal function or whether its effect on blood pressure prove salutary."3.73Does the hyperfiltration of minoxidil result in increased proteinuria and loss of renoprotection conferred by angiotensin inhibition? ( Carter, TB; Dansby, LM; Diskin, CJ; Radcliff, L; Stokes, TJ, 2006)
"Sixty-nine patients with refractory hypertension were treated with minoxidil and in 66 good control of blood pressure was achieved."3.66Improvement of renal function during long-term treatment of severe hypertension with minoxidil. ( Bing, RF; Heagerty, A; Pohl, JE; Russell, GI; Swales, JD; Taverner, D; Thurston, H, 1983)
"Pulmonary hypertension has been described as a possible complication of the antihypertensive vasodilator, minoxidil."3.65The effects of minoxidil on pulmonary and systemic hemodynamics in hypertensive man. ( Grim, CE; Judson, WE; Klotman, PE; Weinberger, MH, 1977)
"Minoxidil is a valuable antihypertensive drug in children but should be used with caution."1.27Severe hypertension in children with renal disease: treatment with minoxidil. ( Kaiser, BA; Maltz, HE; Potter, DE; Puri, HC, 1983)
"Propranolol pretreatment of HT rats decreases the hypotensive effect induced by the three vasodilators."1.26Cardiovascular effects of dihydralazine diazoxide and minoxidil alone or associated with propranolol in renal hypertensive rats. ( Cohen, Y; Lindenbaum, A; Provost, Y; Wepierre, J, 1981)
"Minoxidil was administered to 13 patients with arterial hypertension resistant to ordinary antihypertensive drugs and with various degrees of renal failure."1.26[Treatment of arterial hypertension with minoxidil in renal insufficiency]. ( Cianciaruso, B; Dal Canton, A; Federico, S; Gallo, R; Usberti, M, 1980)
"7 years) with severe essential hypertension (n = 21) and renovascular hypertension (n = 1) were treated with a mean daily dosage of 16."1.26[Minoxidil in treatment resistant hypertension]. ( Furrer, J; Nussberger, J; Reuteler, H; Siegenthaler, W; Studer, A; Tenschert, W; Vetter, W, 1979)
"Minoxidil is a new, effective, investigational antihypertensive drug."1.26Minoxidil-induced hypertrichosis: treatment with calcium thioglycolate depilatory. ( Aeling, JL; Ball, J; Earhart, RN; Nuss, DD, 1977)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199023 (82.14)18.7374
1990's1 (3.57)18.2507
2000's3 (10.71)29.6817
2010's1 (3.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Polizio, AH1
Gorzalczany, SB1
Tomaro, ML1
Halling, SE1
Asling-Monemi, K1
Herthelius, M1
Celsi, G1
Vavilis, G1
Kuru, NK1
Efvergren, M1
Krmar, RT1
Diskin, CJ2
Stokes, TJ1
Dansby, LM1
Radcliff, L1
Carter, TB1
Taverner, D1
Bing, RF1
Heagerty, A1
Russell, GI1
Pohl, JE1
Swales, JD1
Thurston, H1
Puri, HC1
Maltz, HE1
Kaiser, BA1
Potter, DE1
Provost, Y1
Lindenbaum, A1
Cohen, Y1
Wepierre, J1
Panasiuk, E1
Kałczak, M1
Wańkowicz, Z1
Kindler, J2
Glöckner, WM1
Sieberth, HG2
Konrads, A1
Meurer, KA1
Schulz, V1
Vaith, P1
Federico, S1
Dal Canton, A1
Cianciaruso, B1
Gallo, R1
Usberti, M1
Markenson, JA1
Sherman, RL1
Liebau, G1
Hayduk, K1
Tenschert, W1
Vetter, W2
Studer, A1
Reuteler, H1
Furrer, J1
Nussberger, J1
Siegenthaler, W1
Campieri, C1
Stefoni, S1
Martinelli, S1
Feliciangeli, G1
Bonomini, V1
Marquez-Julio, A1
From, GL1
Uldall, PR1
Lindner, A1
Douglas, SW1
Adamson, JW1
Hall, D1
Charocopos, F1
Froer, KL1
Rudolph, W1
Peitz, R1
Werning, C1
Klotman, PE1
Grim, CE1
Weinberger, MH1
Judson, WE1
Earhart, RN1
Ball, J1
Nuss, DD1
Aeling, JL1
Schacht, RA1
Goldstein, D1
Martin, DG1
Langevitz, P1
Buskila, D1
Lee, P1
Hercz, G1
Fenje, P1
Leenen, FH1
Greminger, P1
Foerster, E1
Vetter, H1
Baumgart, P1
Pettinger, WA1
Mitchell, HC1
Wendling, MG1
DuCharme, DW1

Trials

4 trials available for minoxidil and Hypertension, Renal

ArticleYear
Minoxidil therapy in children and young adult patients with renal disease and refractory hypertension: value when multidrug regimens have failed to achieve blood pressure control.
    Journal of human hypertension, 2010, Volume: 24, Issue:8

    Topics: Adolescent; Antihypertensive Agents; Blood Pressure; Child; Drug Resistance; Drug Therapy, Combinati

2010
[Management of treatment-resistant hypertension: comparison of the antihypertensive effect of endralazine and minoxidil (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1981, Sep-11, Volume: 106, Issue:37

    Topics: Adolescent; Adult; Aged; Female; Humans; Hypertension; Hypertension, Renal; Male; Middle Aged; Minox

1981
The effect of minoxidil on blood pressure and plasma renin activity in patients with essential and renal hypertension.
    Klinische Wochenschrift, 1976, Aug-01, Volume: 54, Issue:15

    Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Edema; Female; Humans; Hypertension; Hyperten

1976
Minoxidil and captopril in severe hypertension.
    Klinische Wochenschrift, 1986, Apr-01, Volume: 64, Issue:7

    Topics: Adult; Aged; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Humans; Hypertension; Hype

1986

Other Studies

24 other studies available for minoxidil and Hypertension, Renal

ArticleYear
Lowering arterial pressure delays the oxidative stress generation in a renal experimental model of hypertension.
    Journal of cardiovascular pharmacology, 2009, Volume: 54, Issue:4

    Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Disease Models, Animal; Heme Oxyg

2009
Does the hyperfiltration of minoxidil result in increased proteinuria and loss of renoprotection conferred by angiotensin inhibition?
    Kidney & blood pressure research, 2006, Volume: 29, Issue:1

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive

2006
Minoxidil use in proteinuric renal disease.
    Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti, 2008, Volume: 62, Issue:1

    Topics: Antihypertensive Agents; Blood Pressure; Humans; Hypertension, Renal; Minoxidil; Proteinuria

2008
Improvement of renal function during long-term treatment of severe hypertension with minoxidil.
    The Quarterly journal of medicine, 1983,Spring, Volume: 52, Issue:206

    Topics: Blood Pressure; Creatinine; Humans; Hypertension; Hypertension, Renal; Kidney; Minoxidil; Pyrimidine

1983
Hypertension in chronic renal disease.
    Kidney international, 1982, Volume: 22, Issue:6

    Topics: Adult; Blood Pressure; Captopril; Graft Rejection; Humans; Hypertension, Renal; Kidney Failure, Chro

1982
Severe hypertension in children with renal disease: treatment with minoxidil.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1983, Volume: 3, Issue:1

    Topics: Adolescent; Blood Pressure; Child; Child, Preschool; Follow-Up Studies; Humans; Hypertension, Renal;

1983
Cardiovascular effects of dihydralazine diazoxide and minoxidil alone or associated with propranolol in renal hypertensive rats.
    Archives internationales de pharmacodynamie et de therapie, 1981, Volume: 251, Issue:1

    Topics: Animals; Antihypertensive Agents; Diazoxide; Dihydralazine; Drug Interactions; Hemodynamics; Hyperte

1981
[Minoxidil control of severe arterial hypertension complicating glomerulonephritis].
    Polskie Archiwum Medycyny Wewnetrznej, 1981, Volume: 65, Issue:6

    Topics: Adult; Female; Glomerulonephritis; Humans; Hypertension, Renal; Minoxidil; Pyrimidines

1981
[Treatment of arterial hypertension with minoxidil in renal insufficiency].
    Minerva medica, 1980, Oct-13, Volume: 71, Issue:39

    Topics: Adult; Child, Preschool; Female; Humans; Hypertension, Renal; Hypertrichosis; Kidney Failure, Chroni

1980
Renal involvement in progressive systemic sclerosis: prolonged survival with aggressive antihypertensive management.
    Arthritis and rheumatism, 1979, Volume: 22, Issue:10

    Topics: Adult; Antihypertensive Agents; Cardiomegaly; Digoxin; Drug Therapy, Combination; Female; Furosemide

1979
[Treatment of therapy resistant arterial hypertension with Minoxidil, a peripheral vasodilator agent. Experience of short and long term medication].
    Die Medizinische Welt, 1977, Nov-18, Volume: 28, Issue:46

    Topics: Adult; Female; Humans; Hypertension; Hypertension, Renal; Long-Term Care; Male; Middle Aged; Minoxid

1977
[Minoxidil in treatment resistant hypertension].
    Schweizerische medizinische Wochenschrift, 1979, Dec-08, Volume: 109, Issue:47

    Topics: Adult; Diuretics; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypertension; Hyperten

1979
Severe hypertension in chronic renal failure treated with minoxidil.
    Clinical and experimental hypertension, 1979, Volume: 1, Issue:6

    Topics: Adolescent; Adult; Blood Pressure; Female; Humans; Hypertension, Renal; Kidney Failure, Chronic; Mal

1979
Minoxidil in refractory hypertension: benefits, risks.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1977, Volume: 14

    Topics: Adult; Aged; Diuretics; Female; Glucose Tolerance Test; Humans; Hypertension, Renal; Male; Middle Ag

1977
Propranolol effects in long-term hemodialysis patients with renin-dependent hypertension.
    Annals of internal medicine, 1978, Volume: 88, Issue:4

    Topics: Adult; Blood Pressure; Erythrocytes; Erythropoiesis; Erythropoietin; Hematocrit; Humans; Hypertensio

1978
Use of minoxidil in resistant hypertension. Beneficial effects, adverse reactions and indications.
    Herz, 1978, Volume: 3, Issue:5

    Topics: Adolescent; Adult; Aged; Atenolol; Child; Child, Preschool; Drug Resistance; Female; Furosemide; Hum

1978
[The treatment therapy refractory hypertension with minoxidil].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1978, Issue:84

    Topics: Adult; Female; Humans; Hypertension, Renal; Male; Middle Aged; Minoxidil; Pyrimidines

1978
The effects of minoxidil on pulmonary and systemic hemodynamics in hypertensive man.
    Circulation, 1977, Volume: 55, Issue:2

    Topics: Adult; Blood Pressure; Cardiac Output; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Hyper

1977
Minoxidil-induced hypertrichosis: treatment with calcium thioglycolate depilatory.
    Southern medical journal, 1977, Volume: 70, Issue:4

    Topics: Female; Hair Removal; Humans; Hypertension; Hypertension, Renal; Hypertrichosis; Lupus Erythematosus

1977
Severe hypertension in chronic renal failure treated successfully with Minoxidil.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1975, Volume: 11

    Topics: Adult; Child; Female; Humans; Hypertension, Renal; Kidney Failure, Chronic; Male; Middle Aged; Minox

1975
Scleroderma hypertensive renal crisis and the changing pattern of mortality in systemic sclerosis (scleroderma)
    Nephron, 1991, Volume: 57, Issue:1

    Topics: Adult; Captopril; Female; Humans; Hydralazine; Hypertension, Renal; Kidney; Male; Middle Aged; Minox

1991
Effects of minoxidil on blood pressure and cardiac hypertrophy in two-kidney, one-clip hypertensive rats.
    Canadian journal of physiology and pharmacology, 1985, Volume: 63, Issue:2

    Topics: Animals; Blood Pressure; Body Weight; Cardiomegaly; Drinking; Hypertension, Renal; Male; Minoxidil;

1985
Minoxidil--an alternative to nephrectomy for refractory hypertension.
    The New England journal of medicine, 1973, Jul-26, Volume: 289, Issue:4

    Topics: Adult; Antihypertensive Agents; Arrhythmias, Cardiac; Blood Pressure; Cardiomegaly; Diuretics; Elect

1973
Effects of chronic administration of prostaglandin E1 (PGE1) on arterial blood pressure of unanesthetized hypertensive rats.
    Prostaglandins, 1974, Jul-10, Volume: 7, Issue:1

    Topics: Animals; Blood Pressure; Body Weight; Female; Hypertension; Hypertension, Renal; Kidney; Male; Minox

1974