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minoxidil and Hypertension, Malignant

minoxidil has been researched along with Hypertension, Malignant in 40 studies

Minoxidil: A potent direct-acting peripheral vasodilator (VASODILATOR AGENTS) that reduces peripheral resistance and produces a fall in BLOOD PRESSURE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p371)
minoxidil : A pyrimidine N-oxide that is pyrimidine-2,4-diamine 3-oxide substituted by a piperidin-1-yl group at position 6.

Hypertension, Malignant: A condition of markedly elevated BLOOD PRESSURE with DIASTOLIC PRESSURE usually greater than 120 mm Hg. Malignant hypertension is characterized by widespread vascular damage, PAPILLEDEMA, retinopathy, HYPERTENSIVE ENCEPHALOPATHY, and renal dysfunction.

Research Excerpts

ExcerptRelevanceReference
"Minoxidil in combination with propranolol and diuretics was used in the treatment of 41 patients with severe refractory hypertension due to a spectrum of causes."7.66Minoxidil in the treatment of refractory hypertension due to a spectrum of causes. ( Amend, WJ; McChesney, JA, 1980)
"The BP of four patients with severe hypertension could not be controlled by treatment with a variety of drugs including minoxidil and captopril."7.66Combined treatment with minoxidil and captopril in refractory hypertension. ( Levey, BA; Traub, YM, 1983)
"We examined the effect of long-term blood pressure control on renal function in 41 patients with refractory hypertension by using minoxidil, sympathetic suppressants, and diuretics continuously for 6 months to 7 1/2 years."7.66Renal function during long-term treatment of hypertension with minoxidil: comparison of benign and malignant hypertension. ( Graham, RM; Mitchell, HC; Pettinger, WA, 1980)
"Twenty-six patients were selected for treatment with minoxidil on the basis of hypertension which could not be controlled either because of (1) drug failures and/or (2) side effects of drugs."7.65Minoxidil in severe hypertension: value when conventional drugs have failed. ( Dormois, JC; Nies, AS; Young, JL, 1975)
"Minoxidil is a potent antihypertensive used as an adjunctive agent in refractory hypertension."5.40Minoxidil-associated anorexia in an infant with refractory hypertension. ( Attarian, SJ; Cole, FS; Vesoulis, ZA; Zeller, B, 2014)
"Minoxidil was used in 48 patients with AH of varying clinical forms, 19 of those having the malignant AH syndrome."5.27[Use of angiotensin converting enzyme inhibitor captopril and peripheral vasodilator minoxidil in the treatment of patients with stable and malignant arterial hypertension]. ( Arabidze, GG; Kutsenko, AI; Leshchinskiĭ, PM; Lordkipanidze, NL; Masenko, VP, 1983)
"Minoxidil in combination with propranolol and diuretics was used in the treatment of 41 patients with severe refractory hypertension due to a spectrum of causes."3.66Minoxidil in the treatment of refractory hypertension due to a spectrum of causes. ( Amend, WJ; McChesney, JA, 1980)
"The BP of four patients with severe hypertension could not be controlled by treatment with a variety of drugs including minoxidil and captopril."3.66Combined treatment with minoxidil and captopril in refractory hypertension. ( Levey, BA; Traub, YM, 1983)
"We examined the effect of long-term blood pressure control on renal function in 41 patients with refractory hypertension by using minoxidil, sympathetic suppressants, and diuretics continuously for 6 months to 7 1/2 years."3.66Renal function during long-term treatment of hypertension with minoxidil: comparison of benign and malignant hypertension. ( Graham, RM; Mitchell, HC; Pettinger, WA, 1980)
"Twenty-six patients were selected for treatment with minoxidil on the basis of hypertension which could not be controlled either because of (1) drug failures and/or (2) side effects of drugs."3.65Minoxidil in severe hypertension: value when conventional drugs have failed. ( Dormois, JC; Nies, AS; Young, JL, 1975)
"Felodipine was well tolerated and may be useful in the management of severe hypertension."2.66Felodipine as a replacement for minoxidil in the treatment of severe hypertension. ( MacLeod, D; Muir, AL; Tucker, L; Wathen, CG, 1986)
"Diazoxide was the most effective treatment but was the most difficult and unpleasant to use."2.65Treatment of refractory hypertension. ( Bing, RF; Heagerty, A; Pohl, JE; Russell, GI; Swales, JD; Thurston, H, 1982)
"Minoxidil is a potent antihypertensive used as an adjunctive agent in refractory hypertension."1.40Minoxidil-associated anorexia in an infant with refractory hypertension. ( Attarian, SJ; Cole, FS; Vesoulis, ZA; Zeller, B, 2014)
"Minoxidil was used in 48 patients with AH of varying clinical forms, 19 of those having the malignant AH syndrome."1.27[Use of angiotensin converting enzyme inhibitor captopril and peripheral vasodilator minoxidil in the treatment of patients with stable and malignant arterial hypertension]. ( Arabidze, GG; Kutsenko, AI; Leshchinskiĭ, PM; Lordkipanidze, NL; Masenko, VP, 1983)
"Resistant hypertension was a frequent phenomenon when ganglion blocking agents and hydrallazine were the only effective hypotensive agents."1.26The treatment of resistant hypertension. ( Kincaid-Smith, PS, 1976)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199039 (97.50)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (2.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vesoulis, ZA1
Attarian, SJ1
Zeller, B1
Cole, FS1
Kazda, S1
Garthoff, B1
Luckhaus, G1
Swales, JD2
Bing, RF1
Heagerty, A1
Pohl, JE1
Russell, GI1
Thurston, H1
McChesney, JA1
Amend, WJ1
Mitchell, HC3
Pettinger, WA3
Camel, GH1
Carmody, SE1
Perry, HM2
Arabidze, GG2
Leshchinskiĭ, PM3
Lordkipanidze, NL1
Kutsenko, AI2
Masenko, VP1
Varga, K1
Juhász, I1
Kiss, I1
Székács, B1
Farsang, C1
Traub, YM1
Levey, BA1
Ram, CV2
Graham, RM1
Podjarny, E1
Korzets, K1
Bernheim, J1
Alleyne, GA1
Douglas, R1
Forrester, TE1
Grell, GA1
Morgan, AG1
Nicholson, GD3
Williams, W1
Grim, CE2
Kincaid-Smith, PS1
Weidmann, P1
Keusch, G1
Höffler, D1
Demers, HG1
Markenson, JA1
Sherman, RL1
Luft, FC1
Bloch, R1
Szwed, JJ1
Grim, CM1
Mitnick, PD1
Feig, PU1
Wood, BC1
Sharma, JN1
Crouch, TT1
Mutterperl, RE1
Diamond, FB1
Lowenthal, DT1
Miller, WE1
Flinn, RB1
Dormois, JC1
Young, JL1
Nies, AS1
Aronson, AJ1
Bykov, AV1
Runikhin, AIu1
Iakobashvili, MA1
Nikol'skaia, VV1
Wathen, CG1
MacLeod, D1
Tucker, L1
Muir, AL1
Zaruba, AIu1
Kukharchuk, VV1
Mal'ginov, SV1
Meese, RB1
Redgrave, JE1
Swartz, SL1
Klimenko, VS1
Philipp, T1
Nast, HP1
Acchiardo, SR1
Black, WD1
Britt, L1
McKeown, JW1
Johnson, JG1
Hatch, F1
Koch-Weser, J1

Reviews

4 reviews available for minoxidil and Hypertension, Malignant

ArticleYear
Treating severe hypertension.
    Journal of the Royal College of Physicians of London, 1984, Volume: 18, Issue:1

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Diazoxide; Diuretics; Drug Resistance; Drug Th

1984
Hypertensive crisis.
    Cardiology clinics, 1984, Volume: 2, Issue:2

    Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Dia

1984
[Treatment of therapy-resistant hypertension].
    Schweizerische medizinische Wochenschrift, 1977, Aug-06, Volume: 107, Issue:31

    Topics: Adrenergic beta-Antagonists; Diazoxide; Diuretics; Drug Resistance; Drug Therapy, Combination; Human

1977
Hypertensive cardiovascular emergencies.
    Comprehensive therapy, 1985, Volume: 11, Issue:10

    Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Dia

1985

Trials

5 trials available for minoxidil and Hypertension, Malignant

ArticleYear
Treatment of refractory hypertension.
    Lancet (London, England), 1982, Apr-17, Volume: 1, Issue:8277

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Captopril; Clinical Trials as Topic; Diazoxide

1982
[Therapy-resistant malignant hypertension treated with minoxidil].
    Orvosi hetilap, 1983, Feb-13, Volume: 124, Issue:7

    Topics: Adult; Clinical Trials as Topic; Female; Humans; Hypertension, Malignant; Male; Middle Aged; Minoxid

1983
Long-term effects of minoxidil in the treatment of malignant hypertension in chronic renal failure.
    Journal of clinical pharmacology, 1976, Volume: 16, Issue:10 Pt 1

    Topics: Adolescent; Adult; Blood Pressure; Clinical Trials as Topic; Female; Heart Rate; Humans; Hypertensio

1976
[New approaches to the treatment of stable and malignant arterial hypertension].
    Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR, 1986, Volume: 9, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Benzothiadiazines; Clinical Trials as Topic; Dinoprostone; Diure

1986
Felodipine as a replacement for minoxidil in the treatment of severe hypertension.
    European heart journal, 1986, Volume: 7, Issue:10

    Topics: Aged; Calcium Channel Blockers; Felodipine; Heart Rate; Humans; Hypertension, Malignant; Male; Middl

1986

Other Studies

31 other studies available for minoxidil and Hypertension, Malignant

ArticleYear
Minoxidil-associated anorexia in an infant with refractory hypertension.
    Pharmacotherapy, 2014, Volume: 34, Issue:12

    Topics: Anorexia; Antihypertensive Agents; Diagnosis, Differential; Female; Humans; Hypertension, Malignant;

2014
Mode of antihypertensive action of nitrendipine.
    Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 7

    Topics: Aging; Animals; Antihypertensive Agents; Blood Pressure; Diet; Dihydralazine; Heart; Hypertension; H

1984
Minoxidil in the treatment of refractory hypertension due to a spectrum of causes.
    Journal of cardiovascular pharmacology, 1980, Volume: 2 Suppl 2

    Topics: Acute Disease; Adolescent; Adult; Aged; Blood Pressure; Cerebrovascular Disorders; Chronic Disease;

1980
Renal function in long-term minoxidil-treated patients.
    Journal of cardiovascular pharmacology, 1980, Volume: 2 Suppl 2

    Topics: Adult; Blood Pressure; Clonidine; Creatinine; Diuretics; Female; Humans; Hypertension; Hypertension,

1980
Use of minoxidil in the azotemic patient.
    Journal of cardiovascular pharmacology, 1980, Volume: 2 Suppl 2

    Topics: Adolescent; Adult; Aged; Blood Pressure; Bronchopneumonia; Creatinine; Dose-Response Relationship, D

1980
[Use of angiotensin converting enzyme inhibitor captopril and peripheral vasodilator minoxidil in the treatment of patients with stable and malignant arterial hypertension].
    Kardiologiia, 1983, Volume: 23, Issue:12

    Topics: Adolescent; Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril;

1983
Combined treatment with minoxidil and captopril in refractory hypertension.
    Archives of internal medicine, 1983, Volume: 143, Issue:6

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Captopril; Drug Therapy, Combination; Female; Humans

1983
Renal function during long-term treatment of hypertension with minoxidil: comparison of benign and malignant hypertension.
    Annals of internal medicine, 1980, Volume: 93, Issue:5

    Topics: Adult; Aged; Blood Pressure; Creatinine; Female; Humans; Hypertension; Hypertension, Malignant; Hype

1980
Minoxidil and improvement of renal function in uremic malignant hypertension.
    Annals of internal medicine, 1980, Volume: 93, Issue:5

    Topics: Adult; Blood Pressure; Female; Humans; Hypertension, Malignant; Kidney; Minoxidil; Pyrimidines; Urem

1980
Minoxidil in uremic malignant hypertension.
    Annals of internal medicine, 1981, Volume: 94, Issue:6

    Topics: Female; Humans; Hypertension, Malignant; Middle Aged; Minoxidil; Pyrimidines; Uremia

1981
The effect of minoxidil in improving renal function of patients with malignant hypertension.
    The West Indian medical journal, 1981, Volume: 30, Issue:3

    Topics: Adult; Creatinine; Female; Humans; Hypertension, Malignant; Kidney; Kidney Function Tests; Male; Min

1981
Management of malignant hypertension.
    Comprehensive therapy, 1980, Volume: 6, Issue:5

    Topics: Administration, Oral; Antihypertensive Agents; Blood Pressure; Clonidine; Diazoxide; Diuretics; Drug

1980
The treatment of resistant hypertension.
    Drugs, 1976, Volume: 11 SUPPL 1

    Topics: Adrenergic beta-Antagonists; Chlorothiazide; Diazoxide; Drug Resistance; Drug Therapy, Combination;

1976
[Minoxidil in the treatment of malignant hypertension (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1977, Dec-02, Volume: 102, Issue:48

    Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hyper

1977
Renal involvement in progressive systemic sclerosis: prolonged survival with aggressive antihypertensive management.
    Arthritis and rheumatism, 1979, Volume: 22, Issue:10

    Topics: Adult; Antihypertensive Agents; Cardiomegaly; Digoxin; Drug Therapy, Combination; Female; Furosemide

1979
Minoxidil treatment of malignant hypertension. Recovery of renal function.
    JAMA, 1978, Oct-27, Volume: 240, Issue:18

    Topics: Acute Kidney Injury; Adult; Blood Pressure; Female; Humans; Hypertension, Malignant; Kidney; Male; M

1978
Control of hypertension and reversal of renal failure in scleroderma.
    The New England journal of medicine, 1978, Oct-19, Volume: 299, Issue:16

    Topics: Acute Kidney Injury; Adult; Antihypertensive Agents; Humans; Hydralazine; Hypertension, Malignant; M

1978
Oral minoxidil in the treatment of hypertensive crisis.
    JAMA, 1979, Jan-12, Volume: 241, Issue:2

    Topics: Adolescent; Blood Pressure; Female; Humans; Hypertension, Malignant; Kidney Failure, Chronic; Minoxi

1979
Clinical experience with long-term Minoxidil therapy.
    Delaware medical journal, 1977, Volume: 49, Issue:10

    Topics: Adult; Female; Humans; Hypertension; Hypertension, Malignant; Male; Middle Aged; Minoxidil; Pyrimidi

1977
Minoxidil in severe hypertension: value when conventional drugs have failed.
    American heart journal, 1975, Volume: 90, Issue:3

    Topics: Adult; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Edema; Female;

1975
Letter: Malignant hypertension in children.
    American journal of diseases of children (1960), 1975, Volume: 129, Issue:9

    Topics: Child; Female; Humans; Hypertension, Malignant; Minoxidil; Pyrimidines

1975
Long-term survival after recovery from malignant nephrosclerosis.
    American journal of hypertension, 1988, Volume: 1, Issue:1

    Topics: Acute Kidney Injury; Adult; Female; Follow-Up Studies; Humans; Hypertension, Malignant; Kidney; Male

1988
[Hemodialysis in patients with incorrigible arterial hypertension].
    Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR, 1985, Volume: 8, Issue:1

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Captopril; Female; Glomerulonephritis; Humans; Hyper

1985
Diagnosis and management of malignant hypertension.
    Comprehensive therapy, 1985, Volume: 11, Issue:3

    Topics: Antihypertensive Agents; Female; Humans; Hydralazine; Hypertension, Malignant; Kidney Function Tests

1985
[Results of prolonged use of minoxidil in patients with stable and malignant arterial hypertension].
    Kardiologiia, 1985, Volume: 25, Issue:1

    Topics: Adult; Drug Therapy, Combination; Female; Furosemide; Humans; Hypertension; Hypertension, Malignant;

1985
Cessation of regular haemodialysis therapy in oliguric malignant hypertension treated with minoxidil.
    The West Indian medical journal, 1985, Volume: 34, Issue:4

    Topics: Adult; Anuria; Female; Humans; Hypertension, Malignant; Kidney Failure, Chronic; Minoxidil; Oliguria

1985
[Hypertensive emergencies].
    Der Internist, 1974, Volume: 15, Issue:3

    Topics: Brain Edema; Clonidine; Diazoxide; Digitalis Glycosides; Diuretics; Drug Combinations; Emergencies;

1974
Minoxidil--an alternative to nephrectomy for refractory hypertension.
    The New England journal of medicine, 1973, Jul-26, Volume: 289, Issue:4

    Topics: Adult; Antihypertensive Agents; Arrhythmias, Cardiac; Blood Pressure; Cardiomegaly; Diuretics; Elect

1973
Editoral: Diazoxide in malignant hypertension.
    The Medical journal of Australia, 1974, Oct-26, Volume: 2, Issue:17

    Topics: Diazoxide; Drug Therapy, Combination; Humans; Hypertension, Malignant; Minoxidil; Propranolol

1974
Experience with hemodialysis and renal transplantation in patients with malignant hypertension.
    Proceedings of the Clinical Dialysis and Transplant Forum, 1974, Issue:4

    Topics: Acute Kidney Injury; Adult; Brain Diseases; Diazoxide; Diet Therapy; Female; Follow-Up Studies; Furo

1974
Vasodilation for vasospastic hypertension.
    The New England journal of medicine, 1973, 07-26, Volume: 289, Issue:4

    Topics: Diuretics; Humans; Hypertension; Hypertension, Malignant; Minoxidil; Propranolol; Vascular Resistanc

1973