minoxidil has been researched along with Heart Failure in 27 studies
Minoxidil: A potent direct-acting peripheral vasodilator (VASODILATOR AGENTS) that reduces peripheral resistance and produces a fall in BLOOD PRESSURE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p371)
minoxidil : A pyrimidine N-oxide that is pyrimidine-2,4-diamine 3-oxide substituted by a piperidin-1-yl group at position 6.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Minoxidil, a potent predominant arterial dilator, improves hemodynamics over the short term in patients with heart failure." | 9.05 | Minoxidil in patients with chronic left heart failure: contrasting hemodynamic and clinical effects in a controlled trial. ( Franciosa, JA; Jordan, RA; Leddy, CL; Wilen, MM, 1984) |
| "The hemodynamic response to minoxidil, an orally active, potent vasodilator, was evaluated in 11 patients with severe chronic congestive heart failure (CHF)." | 7.66 | Minoxidil therapy in chronic congestive heart failure: acute plus long-term hemodynamic and clinical study. ( Chatterjee, K; Holly, AN; McKay, CR; Parmley, WW; Ports, TA, 1982) |
| "The effects of acute and chronic oral administration of the vasodilator minoxidil on hemodynamics, oxygen consumption, exercise performance, and clinical status were investigated in 10 patients with severe, chronic heart failure refractory to digitalis and diuretic therapy." | 7.66 | Effects of acute and chronic minoxidil administration on rest and exercise hemodynamics and clinical status in patients with severe, chronic heart failure. ( Nathan, M; Rubin, SA; Siemienczuk, D; Swan, HJ, 1982) |
| "Twenty-six patients were selected for treatment with minoxidil on the basis of hypertension which could not be controlled either because of (1) drug failures and/or (2) side effects of drugs." | 7.65 | Minoxidil in severe hypertension: value when conventional drugs have failed. ( Dormois, JC; Nies, AS; Young, JL, 1975) |
| "Minoxidil appears to be an effective arterial dilating agent in patients with heart failure and resembles hydralazine in its actions." | 5.26 | Effects of minoxidil on hemodynamics in patients with congestive heart failure. ( Cohn, JN; Franciosa, JA, 1981) |
| " Thus, short- and long-term hemodynamic responses to placebo and vasodilators (isosorbide dinitrate, minoxidil and enalapril or captopril) were measured and long-term clinical efficacy was assessed by changes in exercise capacity after 1 to 5 months of vasodilator administration (plus digitalis and diuretic agents) in 46 patients with New York Heart Association functional class II to IV heart failure caused by cardiomyopathy." | 5.05 | Hemodynamic effects of vasodilators and long-term response in heart failure. ( Dunkman, WB; Franciosa, JA; Leddy, CL, 1984) |
| "Minoxidil, a potent predominant arterial dilator, improves hemodynamics over the short term in patients with heart failure." | 5.05 | Minoxidil in patients with chronic left heart failure: contrasting hemodynamic and clinical effects in a controlled trial. ( Franciosa, JA; Jordan, RA; Leddy, CL; Wilen, MM, 1984) |
| "The hemodynamic response to minoxidil, an orally active, potent vasodilator, was evaluated in 11 patients with severe chronic congestive heart failure (CHF)." | 3.66 | Minoxidil therapy in chronic congestive heart failure: acute plus long-term hemodynamic and clinical study. ( Chatterjee, K; Holly, AN; McKay, CR; Parmley, WW; Ports, TA, 1982) |
| "The effects of acute and chronic oral administration of the vasodilator minoxidil on hemodynamics, oxygen consumption, exercise performance, and clinical status were investigated in 10 patients with severe, chronic heart failure refractory to digitalis and diuretic therapy." | 3.66 | Effects of acute and chronic minoxidil administration on rest and exercise hemodynamics and clinical status in patients with severe, chronic heart failure. ( Nathan, M; Rubin, SA; Siemienczuk, D; Swan, HJ, 1982) |
| "A patient with severe, chronic congestive heart failure was unresponsive not only to conventional therapy, but also to nonparenteral nitroglycerin and isosorbide dinitrate; he became nitroprusside dependent." | 3.65 | Combination vasodilator therapy for severe chronic congestive heart failure. ( Chatterjee, K; Drew, D; Klausner, SC; Parmley, WW; Polansky, J; Zacherle, B, 1976) |
| "Twenty-six patients were selected for treatment with minoxidil on the basis of hypertension which could not be controlled either because of (1) drug failures and/or (2) side effects of drugs." | 3.65 | Minoxidil in severe hypertension: value when conventional drugs have failed. ( Dormois, JC; Nies, AS; Young, JL, 1975) |
| "Minoxidil appears to be an effective arterial dilating agent in patients with heart failure and resembles hydralazine in its actions." | 1.26 | Effects of minoxidil on hemodynamics in patients with congestive heart failure. ( Cohn, JN; Franciosa, JA, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (92.59) | 18.7374 |
| 1990's | 1 (3.70) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (3.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takahashi, T | 1 |
| Takei, T | 1 |
| Ito, T | 1 |
| Sakamoto, K | 1 |
| Nara, T | 1 |
| Yagi, K | 1 |
| Fischer, E | 1 |
| Siegenthaler, W | 1 |
| Markham, RV | 1 |
| Gilmore, A | 1 |
| Pettinger, WA | 1 |
| Brater, DC | 1 |
| Corbett, JR | 1 |
| Firth, BG | 1 |
| Martin, WB | 2 |
| Spodick, DH | 1 |
| Zins, GR | 1 |
| Franciosa, JA | 4 |
| Dunkman, WB | 1 |
| Leddy, CL | 2 |
| Schwartz, AB | 1 |
| Chatterjee, K | 3 |
| Braunwald, E | 1 |
| Colucci, WS | 1 |
| Jordan, RA | 1 |
| Wilen, MM | 1 |
| Satinsky, JD | 1 |
| Ciafone, RA | 1 |
| Gould, L | 1 |
| Gopalaswamy, C | 1 |
| Cohn, JN | 2 |
| Packer, M | 1 |
| Meller, J | 1 |
| Medina, N | 1 |
| Yushak, M | 1 |
| Evans, CW | 1 |
| Tucker, SC | 1 |
| McKay, CR | 1 |
| Ports, TA | 1 |
| Holly, AN | 1 |
| Parmley, WW | 2 |
| Nathan, M | 1 |
| Rubin, SA | 3 |
| Siemienczuk, D | 2 |
| Swan, HJ | 2 |
| Nathan, MD | 1 |
| Prause, J | 1 |
| Fouad, FM | 1 |
| Sobota, JT | 1 |
| Carlson, RG | 1 |
| Feenstra, ES | 1 |
| Turcani, M | 1 |
| Jacob, R | 1 |
| Prati, PL | 1 |
| Manfrin, M | 1 |
| Drew, D | 1 |
| Klausner, SC | 1 |
| Polansky, J | 1 |
| Zacherle, B | 1 |
| Dormois, JC | 1 |
| Young, JL | 1 |
| Nies, AS | 1 |
| Young, JB | 1 |
| Leon, CA | 1 |
| Pratt, CM | 1 |
| Shellock, FG | 1 |
5 reviews available for minoxidil and Heart Failure
| Article | Year |
|---|---|
Vasodilator therapy in chronic congestive heart failure.
Topics: Captopril; Chronic Disease; Drug Therapy, Combination; Heart Failure; Hemodynamics; Humans; Hydralaz | 1983 |
Vasodilator therapy of heart failure. Has the promissory note been paid?
Topics: Calcium Channel Blockers; Captopril; Drug Tolerance; Heart Failure; Hemodynamics; Humans; Minoxidil; | 1984 |
Vasodilator therapy of congestive heart failure.
Topics: Aortic Valve Insufficiency; Captopril; Dobutamine; Heart Failure; Humans; Hydralazine; Isosorbide Di | 1980 |
[Vasodilator agents in the treatment of heart failure].
Topics: Heart Failure; Humans; Hydralazine; Isosorbide Dinitrate; Minoxidil; Nitroglycerin; Nitroprusside; P | 1978 |
Potentially deleterious effects of long-term vasodilator therapy in patients with heart failure.
Topics: Angiotensin-Converting Enzyme Inhibitors; Heart; Heart Failure; Hemodynamics; Humans; Hydralazine; M | 1987 |
3 trials available for minoxidil and Heart Failure
| Article | Year |
|---|---|
Central and regional hemodynamic effects and neurohumoral consequences of minoxidil in severe congestive heart failure and comparison to hydralazine and nitroprusside.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Heart Failure; Hemodynamics; Hum | 1983 |
Hemodynamic effects of vasodilators and long-term response in heart failure.
Topics: Antihypertensive Agents; Captopril; Dipeptides; Enalapril; Exercise Test; Heart Failure; Hemodynamic | 1984 |
Minoxidil in patients with chronic left heart failure: contrasting hemodynamic and clinical effects in a controlled trial.
Topics: Aged; Blood Pressure; Cardiac Output; Clinical Trials as Topic; Digoxin; Diuretics; Double-Blind Met | 1984 |
19 other studies available for minoxidil and Heart Failure
| Article | Year |
|---|---|
[A case of minoxidil intoxication].
Topics: Adult; Heart Failure; Humans; Isotonic Solutions; Male; Minoxidil; Norepinephrine; Respiration, Arti | 2014 |
[Vasodilators in heart failure? Basic principles and its role in practice].
Topics: Adrenergic alpha-Antagonists; Captopril; Diazoxide; Furosemide; Heart Failure; Humans; Hydralazine; | 1981 |
Pericardial disorders occurring during open-label study of 1,869 severely hypertensive patients treated with minoxidil.
Topics: Adolescent; Adult; Aged; Arteriovenous Fistula; Cardiac Tamponade; Child; Colitis, Ulcerative; Femal | 1980 |
Chronic heart failure in the elderly: vasodilator therapy.
Topics: Aged; Blood Pressure; Chronic Disease; Female; Follow-Up Studies; Heart Failure; Humans; Hydralazine | 1983 |
Vasodilators in the treatment of congestive heart failure.
Topics: Captopril; Heart Failure; Humans; Hydralazine; Isosorbide Dinitrate; Minoxidil; Nitroglycerin; Nitro | 1983 |
Vasodilator drugs.
Topics: Calcium Channel Blockers; Captopril; Heart Failure; Humans; Hydralazine; Minoxidil; Nitroglycerin; N | 1984 |
Sustained effectiveness of minoxidil in heart failure after development of tolerance to other vasodilator drugs.
Topics: Administration, Oral; Aged; Captopril; Cardiac Catheterization; Drug Tolerance; Heart Failure; Hemod | 1981 |
Pericarditis: a complication of minoxidil therapy.
Topics: Heart Failure; Humans; Hypertension, Pulmonary; Male; Middle Aged; Minoxidil; Pericarditis; Pyrimidi | 1983 |
Effects of minoxidil on hemodynamics in patients with congestive heart failure.
Topics: Adult; Aged; Blood Pressure; Cardiac Output; Cardiomyopathies; Heart Failure; Heart Rate; Hemodynami | 1981 |
Minoxidil therapy in chronic congestive heart failure: acute plus long-term hemodynamic and clinical study.
Topics: Adult; Aged; Body Weight; Cardiac Output; Diuretics; Female; Heart Failure; Hemodynamics; Humans; Ma | 1982 |
Effects of acute and chronic minoxidil administration on rest and exercise hemodynamics and clinical status in patients with severe, chronic heart failure.
Topics: Adult; Aged; Cardiac Output; Female; Follow-Up Studies; Heart Failure; Heart Rate; Hemodynamics; Hum | 1982 |
Accuracy of cardiac output, oxygen uptake, and arteriovenous oxygen difference at rest, during exercise, and after vasodilator therapy in patients with severe, chronic heart failure.
Topics: Adult; Aged; Cardiac Output; Exercise Test; Female; Heart Failure; Humans; Hydralazine; Male; Middle | 1982 |
Vasodilator therapy for congestive heart failure.
Topics: Blood Pressure; Cardiac Output; Heart Failure; Humans; Minoxidil; Myocardial Contraction; Stroke Vol | 1981 |
Minoxidil: right atrial cardiac pathology in animals and in man.
Topics: Adult; Aged; Animals; Dogs; Female; Heart Atria; Heart Failure; Humans; Hypertension; Kidney Failure | 1980 |
Minoxidil accelerates heart failure development in rats with ascending aortic constriction.
Topics: Animals; Aorta; Collagen; Constriction, Pathologic; Heart; Heart Failure; Hydroxyproline; Hypertroph | 1998 |
Combination vasodilator therapy for severe chronic congestive heart failure.
Topics: Chronic Disease; Drug Therapy, Combination; Heart Failure; Hemodynamics; Humans; Hydralazine; Isosor | 1976 |
Minoxidil in severe hypertension: value when conventional drugs have failed.
Topics: Adult; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Edema; Female; | 1975 |
Current indications for vasodilator therapy for left ventricular failure.
Topics: Angiotensin-Converting Enzyme Inhibitors; Drug Therapy, Combination; Heart Failure; Hemodynamics; Hu | 1985 |
Mixed venous blood temperature response to exercise in heart failure patients treated with short-term vasodilators.
Topics: Adult; Aged; Body Temperature; Captopril; Female; Heart Failure; Hemodynamics; Humans; Hydralazine; | 1985 |