minoxidil has been researched along with Edema in 21 studies
Minoxidil: A potent direct-acting peripheral vasodilator (VASODILATOR AGENTS) that reduces peripheral resistance and produces a fall in BLOOD PRESSURE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p371)
minoxidil : A pyrimidine N-oxide that is pyrimidine-2,4-diamine 3-oxide substituted by a piperidin-1-yl group at position 6.
Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The open, long-term antihypertensive, hemodynamic and metabolic effects of betaxolol in combination with furosemide and minoxidil were investigated on 30 male patients with moderate to severe essential hypertension." | 9.07 | Cardiac changes from beta-blocker, diuretic and minoxidil combination in hypertension. ( Berlin, L; Chrysant, C; Chrysant, SG; Sadeghi, M, 1991) |
| "Minoxidil has been administered to 16 patients with severe hypertension and renal failure." | 9.04 | Minoxidil in severe hypertension. ( Mäkelä, M; Oka, M, 1978) |
| "The effect of the new vasodilator, minoxidil, on blood pressure and plasma renin activity was studied in 21 hypertensive patients: 12 patients with essential and 9 with renal hypertension." | 9.04 | The effect of minoxidil on blood pressure and plasma renin activity in patients with essential and renal hypertension. ( Werning, C, 1976) |
| " Twenty patients with severe or moderate hypertension were treated with minoxidil for 284 patient-months." | 9.04 | Treatment of severe and moderate hypertension with minoxidil: experience in twenty-eight patients. ( Dunea, G; Mahurkar, SD; Mamdani, B, 1976) |
| "Eighty-seven patients with intractable hypertension received minoxidil for a mean duration of 27 months (range three months to five years)." | 7.66 | Minoxidil in the management of intractable hypertension. ( Fife, R; Henderson, I; Isles, C; Kennedy, AC; Mackay, A, 1981) |
| "Thirteen patients with severe hypertension were treated with combined minoxidil, propranolol, and furosemide (mean daily doses 33 mg, 475 mg, and 578 mg, respectively) for nine to twenty-five months (mean 13." | 7.65 | Long-term treatment of severe hypertension with minoxidil, propranolol and furosemide. ( Bennet, CM; Blaufuss, A; Wilburn, RL, 1975) |
| "Twenty-six patients were selected for treatment with minoxidil on the basis of hypertension which could not be controlled either because of (1) drug failures and/or (2) side effects of drugs." | 7.65 | Minoxidil in severe hypertension: value when conventional drugs have failed. ( Dormois, JC; Nies, AS; Young, JL, 1975) |
| " Propranolol and diuretics were given to prevent reflex tachycardia and fluid retention." | 7.65 | Severe hypertension. Treatment with minoxidil. ( Dunea, G; Mahurkar, SD; Mamdani, B; Mehta, PK; Shansky, RM, 1975) |
| " After 3 and 6 months of maintenance therapy, blood pressures were measured 24 hours after the previous day's dosing to evaluate the persistence of the antihypertensive effect." | 5.27 | The management of severe hypertension with minoxidil in a once-a-day treatment regimen. ( Bayley, A; Fraser, HS; Hassell, TA; Nicholson, GD, 1985) |
| "The open, long-term antihypertensive, hemodynamic and metabolic effects of betaxolol in combination with furosemide and minoxidil were investigated on 30 male patients with moderate to severe essential hypertension." | 5.07 | Cardiac changes from beta-blocker, diuretic and minoxidil combination in hypertension. ( Berlin, L; Chrysant, C; Chrysant, SG; Sadeghi, M, 1991) |
| "Minoxidil has been administered to 16 patients with severe hypertension and renal failure." | 5.04 | Minoxidil in severe hypertension. ( Mäkelä, M; Oka, M, 1978) |
| "The effect of the new vasodilator, minoxidil, on blood pressure and plasma renin activity was studied in 21 hypertensive patients: 12 patients with essential and 9 with renal hypertension." | 5.04 | The effect of minoxidil on blood pressure and plasma renin activity in patients with essential and renal hypertension. ( Werning, C, 1976) |
| " Twenty patients with severe or moderate hypertension were treated with minoxidil for 284 patient-months." | 5.04 | Treatment of severe and moderate hypertension with minoxidil: experience in twenty-eight patients. ( Dunea, G; Mahurkar, SD; Mamdani, B, 1976) |
| " Eight dogs were over-diuresed with furosemide over a 2-day period, and 9 dogs were subjected to subacute hemorrhage over a similar period." | 3.68 | Renal response to atrial natriuretic peptide in nonedematous sodium-retaining dogs. ( Cernacek, P; Levy, M, 1992) |
| " Using a simple and convenient once-a-day regimen of minoxidil, nadolol, and chlorthalidone, we treated successfully 30 patients with moderate to severe hypertension." | 3.67 | Minoxidil in a once-a-day step-3 antihypertensive program. ( Alveranga, D; Bazilinski, N; Carroll, HJ; Lazar, I; Oh, MS; Uribarri, J, 1985) |
| "Eighty-seven patients with intractable hypertension received minoxidil for a mean duration of 27 months (range three months to five years)." | 3.66 | Minoxidil in the management of intractable hypertension. ( Fife, R; Henderson, I; Isles, C; Kennedy, AC; Mackay, A, 1981) |
| "Thirteen patients with severe hypertension were treated with combined minoxidil, propranolol, and furosemide (mean daily doses 33 mg, 475 mg, and 578 mg, respectively) for nine to twenty-five months (mean 13." | 3.65 | Long-term treatment of severe hypertension with minoxidil, propranolol and furosemide. ( Bennet, CM; Blaufuss, A; Wilburn, RL, 1975) |
| "Twenty-six patients were selected for treatment with minoxidil on the basis of hypertension which could not be controlled either because of (1) drug failures and/or (2) side effects of drugs." | 3.65 | Minoxidil in severe hypertension: value when conventional drugs have failed. ( Dormois, JC; Nies, AS; Young, JL, 1975) |
| " Propranolol and diuretics were given to prevent reflex tachycardia and fluid retention." | 3.65 | Severe hypertension. Treatment with minoxidil. ( Dunea, G; Mahurkar, SD; Mamdani, B; Mehta, PK; Shansky, RM, 1975) |
| "The major concern regarding the use of low-dose oral minoxidil (LDOM) for the treatment of hair loss is the potential risk of systemic adverse effects." | 1.62 | Safety of low-dose oral minoxidil for hair loss: A multicenter study of 1404 patients. ( Bhoyrul, B; Hermosa-Gelbard, A; Jaén-Olasolo, P; Jerjen, R; Jimenez-Cauhe, J; John, JM; Koh, WL; Lo-Sicco, K; Moreno-Arrones, ÓM; Piraccini, BM; Pirmez, R; Poa, JE; Rodrigues-Barata, R; Rudnicka, L; Saceda-Corralo, D; Salas-Callo, CI; Shapiro, J; Sinclair, R; Starace, M; Tosti, A; Trindade de Carvalho, L; Vañó-Galván, S; Vincenzi, C; Waskiel-Burnat, A; Yin, L; Zamorano, JL, 2021) |
| " After 3 and 6 months of maintenance therapy, blood pressures were measured 24 hours after the previous day's dosing to evaluate the persistence of the antihypertensive effect." | 1.27 | The management of severe hypertension with minoxidil in a once-a-day treatment regimen. ( Bayley, A; Fraser, HS; Hassell, TA; Nicholson, GD, 1985) |
| "Minoxidil is a potent, long-acting, orally effective vasodilator that recently became available for general use in the United States." | 1.26 | Evaluation of a new antihypertensive agent. Minoxidil. ( Kosman, ME, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (71.43) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 1 (4.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Melo, DF | 1 |
| Saceda-Corralo, D | 2 |
| Tosti, A | 2 |
| Weffort, F | 1 |
| Carla Jorge, M | 1 |
| de Barros, CC | 1 |
| de Melo Carvalho, R | 1 |
| Starace, M | 2 |
| Mir-Bonafé, JF | 1 |
| Mir-Bonafé, M | 1 |
| Rozas-Muñoz, E | 1 |
| Mir-Bonafé, JM | 1 |
| Vañó-Galván, S | 1 |
| Pirmez, R | 1 |
| Hermosa-Gelbard, A | 1 |
| Moreno-Arrones, ÓM | 1 |
| Rodrigues-Barata, R | 1 |
| Jimenez-Cauhe, J | 1 |
| Koh, WL | 1 |
| Poa, JE | 1 |
| Jerjen, R | 1 |
| Trindade de Carvalho, L | 1 |
| John, JM | 1 |
| Salas-Callo, CI | 1 |
| Vincenzi, C | 1 |
| Yin, L | 1 |
| Lo-Sicco, K | 1 |
| Waskiel-Burnat, A | 1 |
| Zamorano, JL | 1 |
| Jaén-Olasolo, P | 1 |
| Piraccini, BM | 1 |
| Rudnicka, L | 1 |
| Shapiro, J | 1 |
| Sinclair, R | 1 |
| Bhoyrul, B | 1 |
| Kosman, ME | 1 |
| Jackson, RV | 1 |
| Williamson, MM | 1 |
| Seneviratne, B | 1 |
| Gordon, RD | 1 |
| Andersson, O | 1 |
| Sivertsson, R | 1 |
| Mackay, A | 1 |
| Isles, C | 1 |
| Henderson, I | 1 |
| Fife, R | 1 |
| Kennedy, AC | 1 |
| Golterman-Hardenberg, JC | 1 |
| Dey, R | 1 |
| Donald, TG | 1 |
| Oka, M | 1 |
| Mäkelä, M | 1 |
| Ram, CV | 1 |
| Reichgott, MJ | 1 |
| Werning, C | 1 |
| Dunea, G | 2 |
| Mamdani, B | 2 |
| Mahurkar, SD | 2 |
| Wilburn, RL | 1 |
| Blaufuss, A | 1 |
| Bennet, CM | 1 |
| Dormois, JC | 1 |
| Young, JL | 1 |
| Nies, AS | 1 |
| Mehta, PK | 1 |
| Shansky, RM | 1 |
| Levy, M | 1 |
| Cernacek, P | 1 |
| Chrysant, SG | 1 |
| Chrysant, C | 1 |
| Sadeghi, M | 1 |
| Berlin, L | 1 |
| Oh, MS | 1 |
| Uribarri, J | 1 |
| Alveranga, D | 1 |
| Bazilinski, N | 1 |
| Lazar, I | 1 |
| Carroll, HJ | 1 |
| Nicholson, GD | 1 |
| Fraser, HS | 1 |
| Hassell, TA | 1 |
| Bayley, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomised, Crossover Bioavailability Clinical Trial of Oral Minoxidil 1 MG, After Single and Multiple Dose Administration to Healthy Volunteers Under Fasting Conditions.[NCT06015516] | Phase 1 | 14 participants (Anticipated) | Interventional | 2024-02-29 | Not yet recruiting | ||
| International Phase III, Multi Center, Randomized, Double Blind, Placebo and Active Controlled and Parallel Group Clinical Trial to Evaluate the Efficacy and Safety of Oral Minoxidil 1 mg in Female Patients With Androgenetic Alopecia[NCT05888922] | Phase 3 | 520 participants (Anticipated) | Interventional | 2024-03-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for minoxidil and Edema
| Article | Year |
|---|---|
Minoxidil in severe hypertension.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Cardiac Output; Cardiomegaly; Clinical Trials as Top | 1978 |
The effect of minoxidil on blood pressure and plasma renin activity in patients with essential and renal hypertension.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Edema; Female; Humans; Hypertension; Hyperten | 1976 |
Treatment of severe and moderate hypertension with minoxidil: experience in twenty-eight patients.
Topics: Adult; Clinical Trials as Topic; Edema; Female; Humans; Hydralazine; Hypertension; Hypertrichosis; M | 1976 |
Cardiac changes from beta-blocker, diuretic and minoxidil combination in hypertension.
Topics: Betaxolol; Cardiomegaly; Drug Therapy, Combination; Edema; Furosemide; Humans; Hypertension; Male; M | 1991 |
17 other studies available for minoxidil and Edema
| Article | Year |
|---|---|
Frontal edema due to mesotherapy for androgenetic alopecia: A case series.
Topics: Alopecia; Edema; Female; Finasteride; Humans; Male; Mesotherapy; Minoxidil; Retrospective Studies; T | 2022 |
Morning Periorbital Edema Related to Low-Dose Oral Minoxidil.
Topics: Alopecia; Angioedema; Edema; Humans; Minoxidil | 2023 |
Safety of low-dose oral minoxidil for hair loss: A multicenter study of 1404 patients.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Alopecia; Child; Dizziness; Edema; | 2021 |
Safety of low-dose oral minoxidil for hair loss: A multicenter study of 1404 patients.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Alopecia; Child; Dizziness; Edema; | 2021 |
Safety of low-dose oral minoxidil for hair loss: A multicenter study of 1404 patients.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Alopecia; Child; Dizziness; Edema; | 2021 |
Safety of low-dose oral minoxidil for hair loss: A multicenter study of 1404 patients.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Alopecia; Child; Dizziness; Edema; | 2021 |
Evaluation of a new antihypertensive agent. Minoxidil.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Body Fluids; Diuretics; Drug Therapy, Combination; Edem | 1980 |
Long term minoxidil therapy and renal function, cardiac function, hypertrichosis and blood pressure.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Drug Therapy, Combination; Ede | 1983 |
Renal function and vascular resistance during long-term minoxidil treatment of severe hypertension.
Topics: Blood Pressure; Creatinine; Edema; Glomerular Filtration Rate; Headache; Humans; Hypertension; Hyper | 1980 |
Minoxidil in the management of intractable hypertension.
Topics: Adolescent; Adult; Aged; Drug Therapy, Combination; Edema; Female; Furosemide; Hirsutism; Humans; Hy | 1981 |
Minoxidil (loniten).
Topics: Adolescent; Adult; Child; Child, Preschool; Edema; Hirsutism; Humans; Hypertension; Minoxidil; Pyrim | 1980 |
Experiences with the antihypertensive drug minoxidil.
Topics: Adult; Aged; Blood Pressure; Edema; Evaluation Studies as Topic; Female; Heart; Hirsutism; Humans; H | 1980 |
Short and curly.
Topics: Administration, Cutaneous; Alopecia; Diagnosis, Differential; Drug Hypersensitivity; Edema; Humans; | 2000 |
Fluid retention with minoxidil.
Topics: Edema; Humans; Minoxidil; Pyrimidines | 1978 |
Long-term treatment of severe hypertension with minoxidil, propranolol and furosemide.
Topics: Cardiac Catheterization; Drug Therapy, Combination; Echocardiography; Edema; Furosemide; Humans; Hyd | 1975 |
Minoxidil in severe hypertension: value when conventional drugs have failed.
Topics: Adult; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Edema; Female; | 1975 |
Severe hypertension. Treatment with minoxidil.
Topics: Adult; Black People; Drug Evaluation; Edema; Female; Follow-Up Studies; Guanethidine; Humans; Hypert | 1975 |
Renal response to atrial natriuretic peptide in nonedematous sodium-retaining dogs.
Topics: Animals; Atrial Natriuretic Factor; Dogs; Edema; Female; Fludrocortisone; Furosemide; Glomerular Fil | 1992 |
Minoxidil in a once-a-day step-3 antihypertensive program.
Topics: Chlorthalidone; Drug Therapy, Combination; Edema; Female; Humans; Hypertension; Hypertrichosis; Male | 1985 |
The management of severe hypertension with minoxidil in a once-a-day treatment regimen.
Topics: Adult; Aged; Chlorthalidone; Creatinine; Drug Therapy, Combination; Edema; Female; Humans; Hypertens | 1985 |