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minoxidil and Disease Models, Animal

minoxidil has been researched along with Disease Models, Animal in 20 studies

Minoxidil: A potent direct-acting peripheral vasodilator (VASODILATOR AGENTS) that reduces peripheral resistance and produces a fall in BLOOD PRESSURE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p371)
minoxidil : A pyrimidine N-oxide that is pyrimidine-2,4-diamine 3-oxide substituted by a piperidin-1-yl group at position 6.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"As an extension to these observations, we chose to test the efficacy of minoxidil, a drug known to be a hypertrichotic agent, in preventing chemotherapy-induced alopecia in the newborn rat animal model."7.69Protection against cytosine arabinoside-induced alopecia by minoxidil in a rat animal model. ( Hussein, AM, 1995)
"Topical minoxidil has shown some promise for the treatment of male-pattern alopecia and alopecia areata."6.16Minoxidil. ( Fiedler-Weiss, VC, 1987)
" Minoxidil (MXD) is commonly used topically to treat alopecia, but its low absorption rate limits widespread use."5.72Minoxidil-loaded hyaluronic acid dissolving microneedles to alleviate hair loss in an alopecia animal model. ( An, BS; Jeong, JS; Kim, DS; Kim, MJ; Kim, SY; Lee, S; Seong, KY; Yang, SY, 2022)
"Minoxidil (Mx) is a conventional drug for treating androgenetic alopecia, preventing hair loss, and promoting hair growth."3.83Effectiveness of a Layer-by-Layer Microbubbles-Based Delivery System for Applying Minoxidil to Enhance Hair Growth. ( Chen, HK; Liao, AH; Lin, YC; Lu, YJ; Sytwu, HK; Wang, CH, 2016)
"As an extension to these observations, we chose to test the efficacy of minoxidil, a drug known to be a hypertrichotic agent, in preventing chemotherapy-induced alopecia in the newborn rat animal model."3.69Protection against cytosine arabinoside-induced alopecia by minoxidil in a rat animal model. ( Hussein, AM, 1995)
"The authors studied the effects of vasodilator treatment with either hydralazine or minoxidil on gas exchange and lung water accumulation over a 5-h period in canine oleic acid-induced pulmonary edema."3.67Vasodilators worsen gas exchange in dog oleic-acid lung injury. ( Bishop, MJ; Cheney, FW, 1986)
" Minoxidil (MXD) is commonly used topically to treat alopecia, but its low absorption rate limits widespread use."1.72Minoxidil-loaded hyaluronic acid dissolving microneedles to alleviate hair loss in an alopecia animal model. ( An, BS; Jeong, JS; Kim, DS; Kim, MJ; Kim, SY; Lee, S; Seong, KY; Yang, SY, 2022)
"The data demonstrate that hair loss in the AGA mouse is androgen dependent and that this mutant strain can serve as a suitable model for the screening of compounds, such as antiandrogens and vasodilators, which may influence the balding process."1.28Animal models of androgen-dependent disorders of the pilosebaceous apparatus. 1. The androchronogenetic alopecia (AGA) mouse as a model for male-pattern baldness. ( Malloy, V; Matias, JR; Orentreich, N, 1989)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19905 (25.00)18.7374
1990's2 (10.00)18.2507
2000's5 (25.00)29.6817
2010's4 (20.00)24.3611
2020's4 (20.00)2.80

Authors

AuthorsStudies
Solinski, HJ1
Dranchak, P1
Oliphant, E1
Gu, X1
Earnest, TW1
Braisted, J1
Inglese, J1
Hoon, MA1
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Wu, ZJ1
Ibrahim, MM1
Sergesketter, AR1
Schweller, RM1
Phillips, BT1
Klitzman, B1
Kim, MJ1
Seong, KY1
Kim, DS1
Jeong, JS1
Kim, SY1
Lee, S1
Yang, SY1
An, BS1
Anderson, ZT1
Palmer, JW1
Idris, MI1
Villavicencio, KM1
Le, G1
Cowart, J1
Weinstein, DE1
Harris, ML1
Chen, YF2
Chen, LH1
Yeh, YM1
Wu, PY1
Chang, LY1
Chang, JY1
Shen, MR1
Liao, AH1
Lu, YJ1
Lin, YC1
Chen, HK1
Sytwu, HK1
Wang, CH1
Thunhorst, RL1
Beltz, TG1
Johnson, AK1
Polizio, AH1
Gorzalczany, SB1
Tomaro, ML1
Gu, YT1
Xue, YX1
Zhang, H1
Li, Y1
Liang, XY1
Chen, CH1
Sheu, MT1
Wu, AB1
Lin, KP1
Ho, HO1
Pals, DT1
Orley, J1
Hussein, AM1
Kimura, T1
Leenen, FH1
Yuan, B1
Shirai, A1
Ikeda, J1
Kawashima, S1
Tamaoki, T1
Kamiya, T1
Pick, R1
Glick, G1
Matias, JR1
Malloy, V1
Orentreich, N1
Fiedler-Weiss, VC1
Bishop, MJ1
Cheney, FW1

Reviews

2 reviews available for minoxidil and Disease Models, Animal

ArticleYear
Studies on development of hairless descendants of Mexican hairless dogs and their usefulness in dermatological science.
    Experimental animals, 1996, Volume: 45, Issue:1

    Topics: Animals; Blood Cell Count; Breeding; Dermatitis, Allergic Contact; Dermatology; Dihydroxyphenylalani

1996
Minoxidil.
    Dermatologic clinics, 1987, Volume: 5, Issue:3

    Topics: Adolescent; Adult; Aged; Alopecia Areata; Animals; Cells, Cultured; Child; Clinical Trials as Topic;

1987

Trials

1 trial available for minoxidil and Disease Models, Animal

ArticleYear
Minoxidil.
    Dermatologic clinics, 1987, Volume: 5, Issue:3

    Topics: Adolescent; Adult; Aged; Alopecia Areata; Animals; Cells, Cultured; Child; Clinical Trials as Topic;

1987

Other Studies

18 other studies available for minoxidil and Disease Models, Animal

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
The Influence of Topical Vasodilator-Induced Pharmacologic Delay on Cutaneous Flap Viability and Vascular Remodeling.
    Plastic and reconstructive surgery, 2022, Mar-01, Volume: 149, Issue:3

    Topics: Administration, Cutaneous; Animals; Disease Models, Animal; Graft Survival; Iloprost; Male; Minoxidi

2022
Minoxidil-loaded hyaluronic acid dissolving microneedles to alleviate hair loss in an alopecia animal model.
    Acta biomaterialia, 2022, 04-15, Volume: 143

    Topics: Alopecia; Animals; Antineoplastic Agents; Disease Models, Animal; Hyaluronic Acid; Mice; Minoxidil

2022
Topical RT1640 treatment effectively reverses gray hair and stem cell loss in a mouse model of radiation-induced canities.
    Pigment cell & melanoma research, 2021, Volume: 34, Issue:1

    Topics: Administration, Topical; Animals; Cyclosporine; Dermatologic Agents; Disease Models, Animal; Drug Co

2021
Minoxidil is a potential neuroprotective drug for paclitaxel-induced peripheral neuropathy.
    Scientific reports, 2017, 03-28, Volume: 7

    Topics: Alopecia; Animals; Antineoplastic Agents, Phytogenic; Calcium; Cell Line, Tumor; Disease Models, Ani

2017
Effectiveness of a Layer-by-Layer Microbubbles-Based Delivery System for Applying Minoxidil to Enhance Hair Growth.
    Theranostics, 2016, Volume: 6, Issue:6

    Topics: Albumins; Alopecia; Animals; Chitosan; Disease Models, Animal; Drug Delivery Systems; Hair; Mice, In

2016
Hypotension- and osmotically induced thirst in old Brown Norway rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 297, Issue:1

    Topics: Age Factors; Aging; Animals; Blood Pressure; Dehydration; Disease Models, Animal; Diuresis; Drinking

2009
Lowering arterial pressure delays the oxidative stress generation in a renal experimental model of hypertension.
    Journal of cardiovascular pharmacology, 2009, Volume: 54, Issue:4

    Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Disease Models, Animal; Heme Oxyg

2009
Adenosine 5'-triphosphate-sensitive potassium channel activator induces the up-regulation of caveolin-1 expression in a rat brain tumor model.
    Cellular and molecular neurobiology, 2011, Volume: 31, Issue:4

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Capillaries; Caveolin 1; Disease Models, Animal; Evan

2011
Simultaneous effects of tocopheryl polyethylene glycol succinate (TPGS) on local hair growth promotion and systemic absorption of topically applied minoxidil in a mouse model.
    International journal of pharmaceutics, 2005, Dec-08, Volume: 306, Issue:1-2

    Topics: Administration, Topical; Alopecia; Animals; Disease Models, Animal; Drug Carriers; Hair; Male; Mice;

2005
A nonhuman primate model for evaluating the potential of antihypertensive drugs to cause orthostatic hypotension.
    Journal of pharmacological methods, 1983, Volume: 9, Issue:3

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Chlorisondamine; Disease Models, Animal; Hypotensi

1983
Protection against cytosine arabinoside-induced alopecia by minoxidil in a rat animal model.
    International journal of dermatology, 1995, Volume: 34, Issue:7

    Topics: Alopecia; Animals; Animals, Newborn; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Disease Mo

1995
Mortality after coronary artery occlusion in different models of cardiac hypertrophy in rats.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:2

    Topics: Animals; Arteriovenous Shunt, Surgical; Blood Pressure; Cardiomegaly; Coronary Disease; Coronary Ves

2001
KF19418, a new compound for hair growth promotion in vitro and in vivo mouse models.
    Journal of dermatological science, 2001, Volume: 25, Issue:3

    Topics: Alopecia; Animals; Cells, Cultured; Culture Techniques; Dermatologic Agents; Disease Models, Animal;

2001
Effects of propranolol, minoxidil, and clofibrate on cholesterol-induced atherosclerosis in stumptail macaques (Macaca arctoides).
    Atherosclerosis, 1977, Volume: 27, Issue:1

    Topics: Animals; Aorta; Arteriosclerosis; Cholesterol; Clofibrate; Coronary Disease; Coronary Vessels; Diet,

1977
Animal models of androgen-dependent disorders of the pilosebaceous apparatus. 1. The androchronogenetic alopecia (AGA) mouse as a model for male-pattern baldness.
    Archives of dermatological research, 1989, Volume: 281, Issue:4

    Topics: Alopecia; Androgens; Animals; Antihypertensive Agents; Disease Models, Animal; Female; Male; Mice; M

1989
Vasodilators worsen gas exchange in dog oleic-acid lung injury.
    Anesthesiology, 1986, Volume: 64, Issue:4

    Topics: Animals; Cardiac Output; Disease Models, Animal; Dogs; Hemodynamics; Hydralazine; Minoxidil; Oleic A

1986