minoxidil has been researched along with Cardiovascular Diseases in 5 studies
Minoxidil: A potent direct-acting peripheral vasodilator (VASODILATOR AGENTS) that reduces peripheral resistance and produces a fall in BLOOD PRESSURE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p371)
minoxidil : A pyrimidine N-oxide that is pyrimidine-2,4-diamine 3-oxide substituted by a piperidin-1-yl group at position 6.
Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Minoxidil and other potent vasodilators cause coronary arterial injury, right atrial hemorrhagic lesions, and subendocardial necrosis in dogs." | 3.67 | Pathogenesis of cardiovascular alterations in dogs treated with minoxidil. ( Carlson, RG; DuCharme, DW; Humphrey, SJ; Mesfin, GM; Piper, RC; Zins, GR, 1989) |
| "Minoxidil is an antihypertensive vasodilator with no known capability of inducing human cardiovascular pathology; however, the compound does cause a late, canine-specific lesion of the right atrium and acute right atrial and ventricular papillary muscle changes." | 2.38 | Review of cardiovascular findings in humans treated with minoxidil. ( Sobota, JT, 1989) |
| "The treatment with minoxidil induced myocardial necrosis, coronary arteriopathy and degeneration of renal tubules in animals treated with 150 mg/kg or 200 mg/kg." | 1.35 | Cardiovascular toxicity of minoxidil in the marmoset. ( Bonnet, P; Daguès, N; Eder, V; Hanton, G; Rochefort, GY; Sobry, C, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hanton, G | 1 |
| Sobry, C | 1 |
| Daguès, N | 1 |
| Rochefort, GY | 1 |
| Bonnet, P | 1 |
| Eder, V | 1 |
| Georgala, S | 1 |
| Befon, A | 1 |
| Maniatopoulou, E | 1 |
| Georgala, C | 1 |
| Atwal, KS | 1 |
| Mesfin, GM | 1 |
| Piper, RC | 1 |
| DuCharme, DW | 1 |
| Carlson, RG | 1 |
| Humphrey, SJ | 1 |
| Zins, GR | 1 |
| Sobota, JT | 1 |
2 reviews available for minoxidil and Cardiovascular Diseases
| Article | Year |
|---|---|
Pharmacology and structure-activity relationships for KATP modulators: tissue-selective KATP openers.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Antihypertensive Agents; Benzopyrans; Cardiovasc | 1994 |
Review of cardiovascular findings in humans treated with minoxidil.
Topics: Animals; Cardiovascular Diseases; Humans; Minoxidil | 1989 |
3 other studies available for minoxidil and Cardiovascular Diseases
| Article | Year |
|---|---|
Cardiovascular toxicity of minoxidil in the marmoset.
Topics: Animals; Blood Chemical Analysis; Callithrix; Cardiovascular Diseases; Cyclic Nucleotide Phosphodies | 2008 |
Topical use of minoxidil in children and systemic side effects.
Topics: Administration, Topical; Adolescent; Alopecia Areata; Cardiovascular Diseases; Child; Female; Follow | 2007 |
Pathogenesis of cardiovascular alterations in dogs treated with minoxidil.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Cardiovascular Diseases; Carotid Sinus; Corona | 1989 |