minoxidil has been researched along with Brain Neoplasms in 5 studies
Minoxidil: A potent direct-acting peripheral vasodilator (VASODILATOR AGENTS) that reduces peripheral resistance and produces a fall in BLOOD PRESSURE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p371)
minoxidil : A pyrimidine N-oxide that is pyrimidine-2,4-diamine 3-oxide substituted by a piperidin-1-yl group at position 6.
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, we investigated whether, intravenously administered, ATP-sensitive potassium channel (K(ATP)) activator (minoxidil sulfate; MS) increases temozolomide and Herceptin delivery to brain tumors to induce anti-tumor activity and increase survival in nude mice with Glioblastoma multiforme (GBM) cells." | 3.75 | Activation of KATP channels increases anticancer drug delivery to brain tumors and survival. ( Khaitan, D; Meister, EA; Ningaraj, NS; Sankpal, UT; Vats, T, 2009) |
| "The expression of potassium channels in brain tumors is variable, which may be associated with different tumor permeability to therapeutic agents among patients." | 2.73 | Different effects of KCa and KATP agonists on brain tumor permeability between syngeneic and allogeneic rat models. ( Bayan, JA; Black, KL; Espinoza, AJ; Hu, J; Irvin, D; Ko, MK; Konda, BM; Ong, JM; Sacapano, MR; Shu, Y; Wang, X; Yin, D, 2008) |
| "MS infusion in rats with brain tumors significantly increased transport vesicle density in tumor capillary endothelial and tumor cells." | 1.32 | Adenosine 5'-triphosphate-sensitive potassium channel-mediated blood-brain tumor barrier permeability increase in a rat brain tumor model. ( Black, KL; Ningaraj, NS; Rao, MK, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gu, YT | 2 |
| Xue, YX | 2 |
| Wang, YF | 1 |
| Wang, JH | 1 |
| Chen, X | 1 |
| ShangGuan, QR | 1 |
| Lian, Y | 1 |
| Zhong, L | 1 |
| Meng, YN | 1 |
| Black, KL | 2 |
| Yin, D | 1 |
| Konda, BM | 1 |
| Wang, X | 1 |
| Hu, J | 1 |
| Ko, MK | 1 |
| Bayan, JA | 1 |
| Sacapano, MR | 1 |
| Espinoza, AJ | 1 |
| Ong, JM | 1 |
| Irvin, D | 1 |
| Shu, Y | 1 |
| Ningaraj, NS | 2 |
| Sankpal, UT | 1 |
| Khaitan, D | 1 |
| Meister, EA | 1 |
| Vats, T | 1 |
| Zhang, H | 1 |
| Li, Y | 1 |
| Liang, XY | 1 |
| Rao, MK | 1 |
1 trial available for minoxidil and Brain Neoplasms
| Article | Year |
|---|---|
Different effects of KCa and KATP agonists on brain tumor permeability between syngeneic and allogeneic rat models.
Topics: Animals; Benzimidazoles; Blood-Brain Barrier; Blotting, Western; Brain Neoplasms; Capillary Permeabi | 2008 |
4 other studies available for minoxidil and Brain Neoplasms
| Article | Year |
|---|---|
Minoxidil sulfate induced the increase in blood-brain tumor barrier permeability through ROS/RhoA/PI3K/PKB signaling pathway.
Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Capillary Permeability; Claudins; Dose-Response Relat | 2013 |
Activation of KATP channels increases anticancer drug delivery to brain tumors and survival.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineopl | 2009 |
Adenosine 5'-triphosphate-sensitive potassium channel activator induces the up-regulation of caveolin-1 expression in a rat brain tumor model.
Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Capillaries; Caveolin 1; Disease Models, Animal; Evan | 2011 |
Adenosine 5'-triphosphate-sensitive potassium channel-mediated blood-brain tumor barrier permeability increase in a rat brain tumor model.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Blood-Brain Barrier; B | 2003 |