Page last updated: 2024-10-31

minoxidil and Body Weight

minoxidil has been researched along with Body Weight in 33 studies

Minoxidil: A potent direct-acting peripheral vasodilator (VASODILATOR AGENTS) that reduces peripheral resistance and produces a fall in BLOOD PRESSURE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p371)
minoxidil : A pyrimidine N-oxide that is pyrimidine-2,4-diamine 3-oxide substituted by a piperidin-1-yl group at position 6.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"In the present study, we evaluated the effects of blockade of the RAS by the angiotensin-converting enzyme inhibitor enalapril and the angiotensin II receptor blocker losartan on left ventricular (LV) and right ventricular mass and LV dilation in relation to changes in central hemodynamics during the maintenance of minoxidil and aortocaval shunt-induced cardiac hypertrophy."7.69Effects of enalapril versus losartan on regression of volume overload-induced cardiac hypertrophy in rats. ( Leenen, FH; Ruzicka, M; Yuan, B, 1994)
"The antihypertensive and tissue-protective effects of nitrendipine were studied after long-term treatment of rats with experimental hypertension."7.68Long-term protective effects of nitrendipine in experimental hypertension. ( Kazda, S; Knorr, A; Neuser, D; Seuter, F; Stasch, JP, 1991)
"Five patients presenting with severe hypertension who failed to exhibit diastolic blood pressures less than 120 mm Hg following the oral administration of propranolol (60--80 mg) and furosemide (40 mg) received minoxidil (20 mg, p."7.66Rapid reduction of severe hypertension with minoxidil. ( Alpert, MA; Bauer, JH, 1980)
"The hemodynamic response to minoxidil, an orally active, potent vasodilator, was evaluated in 11 patients with severe chronic congestive heart failure (CHF)."7.66Minoxidil therapy in chronic congestive heart failure: acute plus long-term hemodynamic and clinical study. ( Chatterjee, K; Holly, AN; McKay, CR; Parmley, WW; Ports, TA, 1982)
"The efficacy and side effects of two potent vasodilatators, namely diazoxide and minoxidil given orally, were compared in 11 patients who had hypertension refractory to conventional drug treatment."7.66[Comparison of oral diazoxide and minoxidil in refractory hypertension]. ( Glück, Z; Grimm, M; Keusch, G; Meier, A; Minder, I; Reubi, FC; Weidmann, P, 1980)
"The mechanism of minoxidil-induced cardiac hypertrophy and its consequences for the myocardium have not been determined."5.29Structural and functional consequences of minoxidil-induced cardiac hypertrophy. ( Cifani, JR; Khairallah, PA; Milovanovic, M; Moravec, CS; Ruhe, T, 1994)
"Minoxidil treatment lowered blood pressure from 178/112 +/- 8/5 mm Hg (means +/- SEM) to 14/95 +/- 6/3 mm Hg."5.26Treatment of drug-resistant hypertension with minoxidil or angiotensin-converting enzyme inhibitor: blood pressure, renin, aldosterone, and electrolyte responses. ( Baer, L; Radichevich, I; Williams, GS, 1980)
"In the present study, we evaluated the effects of blockade of the RAS by the angiotensin-converting enzyme inhibitor enalapril and the angiotensin II receptor blocker losartan on left ventricular (LV) and right ventricular mass and LV dilation in relation to changes in central hemodynamics during the maintenance of minoxidil and aortocaval shunt-induced cardiac hypertrophy."3.69Effects of enalapril versus losartan on regression of volume overload-induced cardiac hypertrophy in rats. ( Leenen, FH; Ruzicka, M; Yuan, B, 1994)
"The antihypertensive and tissue-protective effects of nitrendipine were studied after long-term treatment of rats with experimental hypertension."3.68Long-term protective effects of nitrendipine in experimental hypertension. ( Kazda, S; Knorr, A; Neuser, D; Seuter, F; Stasch, JP, 1991)
"7 mm Hg by applying 1 mg/kg body weight minoxidil twice a day orally."3.67[Kidney function in spontaneously hypertensive rats under minoxidil treatment]. ( Hagemann, I; Kruse, I; Massow, S; Moritz, V; Pietsch, R; Scholze, J; Schürer, M; Siewert, H; Strangfeld, D; Su, LM, 1987)
"Five patients presenting with severe hypertension who failed to exhibit diastolic blood pressures less than 120 mm Hg following the oral administration of propranolol (60--80 mg) and furosemide (40 mg) received minoxidil (20 mg, p."3.66Rapid reduction of severe hypertension with minoxidil. ( Alpert, MA; Bauer, JH, 1980)
"The systemic, cardiovascular hemodynamic and biochemical interactions between clonidine and minoxidil were studied in ten patients with refractory and/or accelerated hypertension."3.66Cardiovascular hemodynamic interactions between clonidine and minoxidil in hypertensive patients. ( Angeli-Greaves, M; Hernandez-Pieretti, O; Morillo, J; Silva, H; Urbina-Quintana, A; Velasco, M, 1983)
"The hemodynamic response to minoxidil, an orally active, potent vasodilator, was evaluated in 11 patients with severe chronic congestive heart failure (CHF)."3.66Minoxidil therapy in chronic congestive heart failure: acute plus long-term hemodynamic and clinical study. ( Chatterjee, K; Holly, AN; McKay, CR; Parmley, WW; Ports, TA, 1982)
"We examined the hemodynamic interaction between clonidine, a centrally acting antiadrenergic drug, and minoxidil, a potent antihypertensive vasodilator in 10 inpatients with refractory or accelerated hypertension or both."3.66Systemic and cardiac hemodynamic interactions between clonidine and minoxidil. ( Aliendres, R; Andrews-Figueroa, P; Hernańdez-Pieretti, O; Morillo, J; Ramiŕez, A; Urbina-Quintana, A; Velasco, M, 1981)
"The efficacy and side effects of two potent vasodilatators, namely diazoxide and minoxidil given orally, were compared in 11 patients who had hypertension refractory to conventional drug treatment."3.66[Comparison of oral diazoxide and minoxidil in refractory hypertension]. ( Glück, Z; Grimm, M; Keusch, G; Meier, A; Minder, I; Reubi, FC; Weidmann, P, 1980)
"Eight patients with arteriosclerotic systolic hypertension whose blood pressure had been nonresponsive to conventional antihypertensive therapy, were given minoxidil in daily doses of 4 to 15 mg."3.66Hazards in treatment of systolic hypertension. ( Aygen, MM; Rosenfeld, JB; Traub, YM, 1979)
"The mechanism of minoxidil-induced cardiac hypertrophy and its consequences for the myocardium have not been determined."1.29Structural and functional consequences of minoxidil-induced cardiac hypertrophy. ( Cifani, JR; Khairallah, PA; Milovanovic, M; Moravec, CS; Ruhe, T, 1994)
"Minoxidil treatment for 8 weeks in both strains resulted in a decrease in mean arterial pressure and increases in ventricular weight to body weight ratios, plasma IR-ANP concentrations (in WKY from 133 +/- 20 to 281 +/- 34 pg ml-1, P less than 0."1.28Release of atrial natriuretic peptide from rat myocardium in vitro: effect of minoxidil-induced hypertrophy. ( Kinnunen, P; Leppäluoto, J; Ruskoaho, H; Taskinen, T, 1990)
"Treatment with hydralazine did not affect left ventricular weight and caused a small increase in the weight of the right ventricle."1.27Effects of arterial vasodilators on cardiac hypertrophy and sympathetic activity in rats. ( Leenen, FH; Tsoporis, J, 1988)
"Minoxidil is a potent antihypertensive vasodilator."1.27Minoxidil does not possess androgenic activity. ( Broulik, PD; Horký, K, 1988)
"Clonidine was given in doses of 0."1.26Clonidine and prazosin effects in hypernoradrenergic vasodilator-treated and beta-blocker-treated patients. ( Mitchell, HC; Pettinger, WA, 1981)
"Minoxidil treatment lowered blood pressure from 178/112 +/- 8/5 mm Hg (means +/- SEM) to 14/95 +/- 6/3 mm Hg."1.26Treatment of drug-resistant hypertension with minoxidil or angiotensin-converting enzyme inhibitor: blood pressure, renin, aldosterone, and electrolyte responses. ( Baer, L; Radichevich, I; Williams, GS, 1980)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199025 (75.76)18.7374
1990's5 (15.15)18.2507
2000's1 (3.03)29.6817
2010's1 (3.03)24.3611
2020's1 (3.03)2.80

Authors

AuthorsStudies
Sanabria, B1
Vanzela, TN1
Miot, HA1
Müller Ramos, P1
Coquand-Gandit, M1
Jacob, MP1
Fhayli, W1
Romero, B1
Georgieva, M1
Bouillot, S1
Estève, E1
Andrieu, JP1
Brasseur, S1
Bouyon, S1
Garcia-Honduvilla, N1
Huber, P1
Buján, J1
Atanasova, M1
Faury, G1
Ong, SL1
Zhang, Y1
Sutton, M1
Whitworth, JA1
Mitchell, HC2
Pettinger, WA2
Javier, R1
Dumler, F1
Park, JH1
Bok, DV1
Riley, RW1
Levin, NW1
Bauer, JH2
Alpert, MA1
Baer, L1
Radichevich, I1
Williams, GS1
Velasco, M2
Silva, H1
Morillo, J2
Urbina-Quintana, A2
Hernandez-Pieretti, O2
Angeli-Greaves, M1
Johnson, BF1
Black, HR1
Beckner, R1
Weiner, B1
Angeletti, F1
Záruba, K1
Rohacek, M1
Grauer, W1
McKay, CR1
Chatterjee, K1
Ports, TA1
Holly, AN1
Parmley, WW1
Bianchetti, MG1
Weidmann, P3
Boehringer, K1
Link, L1
Schiffl, H1
Beretta-Piccoli, C1
Colombo, JP1
Andrews-Figueroa, P1
Ramiŕez, A1
Aliendres, R1
Meier, A1
Glück, Z1
Keusch, G1
Grimm, M1
Minder, I1
Reubi, FC1
Ruzicka, M1
Yuan, B2
Leenen, FH5
Moravec, CS1
Ruhe, T1
Cifani, JR1
Milovanovic, M1
Khairallah, PA1
Pedersen, OL1
Keusch, GW1
Campese, V1
Lee, DB1
Upham, AT1
Massry, SG1
Larochelle, P1
Hamet, P1
Beroniade, V1
Kuchel, O1
Traub, YM1
Aygen, MM1
Rosenfeld, JB1
Ryan, JR1
Jain, AK1
McMahon, FG1
Knorr, A1
Kazda, S1
Neuser, D1
Stasch, JP1
Seuter, F1
Kinnunen, P1
Taskinen, T1
Leppäluoto, J2
Ruskoaho, H2
Fields, N1
Tsoporis, J2
Lee, HC1
Redman, HC1
Reams, GP1
Fenje, P1
Broulik, PD1
Horký, K1
Hagemann, I1
Su, LM1
Strangfeld, D1
Pietsch, R1
Kruse, I1
Schürer, M1
Siewert, H1
Moritz, V1
Massow, S1
Scholze, J1
Wendling, MG1
DuCharme, DW1

Reviews

1 review available for minoxidil and Body Weight

ArticleYear
Minoxidil therapy in refractory hypertension analysis of 155 patients.
    Nephron, 1978, Volume: 21, Issue:1

    Topics: Adult; Animals; Body Weight; Drug Therapy, Combination; Female; Humans; Hypertension; Hypertrichosis

1978

Trials

4 trials available for minoxidil and Body Weight

ArticleYear
A comparison of minoxidil and hydralazine in non-azotemic hypertensives.
    Journal of hypertension, 1983, Volume: 1, Issue:1

    Topics: Adult; Blood Pressure; Body Weight; Female; Heart Rate; Humans; Hydralazine; Hypertension; Male; Mid

1983
Minoxidil in severe hypertension.
    European journal of clinical pharmacology, 1978, Nov-09, Volume: 14, Issue:1

    Topics: Adult; Blood Pressure; Body Weight; Clinical Trials as Topic; Female; Heart Rate; Humans; Hypertensi

1978
Minoxidil treatment of severe hypertension.
    Current therapeutic research, clinical and experimental, 1975, Volume: 17, Issue:1

    Topics: Adult; Blood Pressure; Blood Urea Nitrogen; Body Weight; Diuretics; Drug Therapy, Combination; Elect

1975
Pseudo renal artery stenosis (PRAS) syndrome.
    American journal of hypertension, 1989, Volume: 2, Issue:5 Pt 1

    Topics: Angiography; Blood Pressure; Body Weight; Creatinine; Double-Blind Method; Enalapril; Humans; Hydral

1989

Other Studies

28 other studies available for minoxidil and Body Weight

ArticleYear
Adverse effects of low-dose oral minoxidil for androgenetic alopecia in 435 patients.
    Journal of the American Academy of Dermatology, 2021, Volume: 84, Issue:4

    Topics: Adult; Alopecia; Body Weight; Dermatologic Agents; Headache; Humans; Hypertrichosis; Male; Minoxidil

2021
Chronic Treatment with Minoxidil Induces Elastic Fiber Neosynthesis and Functional Improvement in the Aorta of Aged Mice.
    Rejuvenation research, 2017, Volume: 20, Issue:3

    Topics: Aging; Animals; Aorta; Biomechanical Phenomena; Blood Pressure; Body Weight; Collagen; Elastic Tissu

2017
Hemodynamics of dexamethasone-induced hypertension in the rat.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2009, Volume: 32, Issue:10

    Topics: Animals; Antihypertensive Agents; Body Fluids; Body Weight; Cardiac Output; Dexamethasone; Heart Rat

2009
Clonidine and prazosin effects in hypernoradrenergic vasodilator-treated and beta-blocker-treated patients.
    Clinical pharmacology and therapeutics, 1981, Volume: 30, Issue:3

    Topics: Adrenergic beta-Antagonists; Blood Pressure; Body Weight; Clonidine; Diastole; Diuretics; Female; Hu

1981
Long-term treatment with minoxidil in patients with severe renal failure.
    Journal of cardiovascular pharmacology, 1980, Volume: 2 Suppl 2

    Topics: Acute Kidney Injury; Adult; Body Weight; Female; Furosemide; Humans; Hypertension; Hypertension, Pul

1980
Rapid reduction of severe hypertension with minoxidil.
    Journal of cardiovascular pharmacology, 1980, Volume: 2 Suppl 2

    Topics: Adult; Blood Pressure; Body Weight; Dose-Response Relationship, Drug; Female; Furosemide; Hemodynami

1980
Treatment of drug-resistant hypertension with minoxidil or angiotensin-converting enzyme inhibitor: blood pressure, renin, aldosterone, and electrolyte responses.
    Journal of cardiovascular pharmacology, 1980, Volume: 2 Suppl 2

    Topics: Adult; Aldosterone; Blood Pressure; Body Weight; Captopril; Creatinine; Drug Resistance; Female; Hum

1980
Cardiovascular hemodynamic interactions between clonidine and minoxidil in hypertensive patients.
    Chest, 1983, Volume: 83, Issue:2 Suppl

    Topics: Adult; Blood Pressure; Body Weight; Clonidine; Dopamine beta-Hydroxylase; Drug Interactions; Heart R

1983
[Fluid retention with pericardial effusion in minoxidil therapy (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1982, Jun-25, Volume: 107, Issue:25

    Topics: Body Weight; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Minoxidil; Pericardia

1982
Minoxidil therapy in chronic congestive heart failure: acute plus long-term hemodynamic and clinical study.
    American heart journal, 1982, Volume: 104, Issue:3

    Topics: Adult; Aged; Body Weight; Cardiac Output; Diuretics; Female; Heart Failure; Hemodynamics; Humans; Ma

1982
Comparative evaluation of the new vasodilator carprazidil and minoxidil in the treatment of moderate to severe hypertension.
    European journal of clinical pharmacology, 1982, Volume: 23, Issue:6

    Topics: Adult; Aged; Blood Pressure; Body Weight; Creatinine; Electrolytes; Female; Heart Rate; Hormones; Hu

1982
Systemic and cardiac hemodynamic interactions between clonidine and minoxidil.
    Clinical pharmacology and therapeutics, 1981, Volume: 30, Issue:2

    Topics: Adult; Blood Pressure; Body Weight; Clonidine; Female; Heart; Heart Rate; Hemodynamics; Humans; Hype

1981
[Comparison of oral diazoxide and minoxidil in refractory hypertension].
    Klinische Wochenschrift, 1980, Jul-01, Volume: 58, Issue:13

    Topics: Blood Glucose; Blood Pressure; Body Weight; Diazoxide; Diuretics; Drug Therapy, Combination; Electro

1980
Effects of enalapril versus losartan on regression of volume overload-induced cardiac hypertrophy in rats.
    Circulation, 1994, Volume: 90, Issue:1

    Topics: Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Volume; Body Weight; Cardiomegaly; Coron

1994
Structural and functional consequences of minoxidil-induced cardiac hypertrophy.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:1

    Topics: Animals; Body Weight; Cardiomegaly; Heart; Male; Minoxidil; Myocardial Contraction; Myocardium; Papi

1994
[Treatment of severe hypertension with minoxidil combined with beta-blocking agents and diuretics].
    Ugeskrift for laeger, 1975, Dec-29, Volume: 138, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Body Weight; Diuretics; Drug Therapy, Combination; Female;

1975
Hazards in treatment of systolic hypertension.
    American heart journal, 1979, Volume: 97, Issue:2

    Topics: Aged; Arteriosclerosis; Body Weight; Coronary Disease; Diuretics; Female; Follow-Up Studies; Humans;

1979
Chronic arterial vasodilation, central hemodynamics, and cardiac hypertrophy in spontaneously hypertensive rats.
    Journal of cardiovascular pharmacology, 1992, Volume: 19, Issue:6

    Topics: Animals; Arteries; Blood Pressure; Body Weight; Cardiac Output; Cardiomegaly; Drinking; Heart Rate;

1992
Long-term protective effects of nitrendipine in experimental hypertension.
    Journal of cardiovascular pharmacology, 1991, Volume: 18 Suppl 5

    Topics: Animals; Arteriosclerosis; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Endothelins; Hydr

1991
Release of atrial natriuretic peptide from rat myocardium in vitro: effect of minoxidil-induced hypertrophy.
    British journal of pharmacology, 1990, Volume: 99, Issue:4

    Topics: Animals; Atrial Natriuretic Factor; Body Weight; Cardiomegaly; Hemodynamics; In Vitro Techniques; Ki

1990
Differential effects of the calcium antagonist, nisoldipine, versus the arterial vasodilator, minoxidil, on ventricular anatomy, intravascular volume, and sympathetic activity in rats.
    Journal of cardiovascular pharmacology, 1989, Volume: 14, Issue:6

    Topics: Animals; Blood Volume; Body Weight; Catecholamines; Drinking; Eating; Heart; In Vitro Techniques; Ma

1989
The effect of triple drug therapy on renal function in patients with essential hypertension.
    Journal of clinical pharmacology, 1989, Volume: 29, Issue:9

    Topics: Adrenergic beta-Antagonists; Aged; Aldosterone; Antihypertensive Agents; Atenolol; Betaxolol; Blood

1989
Effects of arterial vasodilators on cardiac hypertrophy and sympathetic activity in rats.
    Hypertension (Dallas, Tex. : 1979), 1988, Volume: 11, Issue:4

    Topics: Animals; Blood Pressure; Blood Volume; Body Weight; Cardiomegaly; Epinephrine; Heart; Heart Rate; He

1988
Immunoreactive atrial natriuretic peptide in ventricles, atria, hypothalamus, and plasma of genetically hypertensive rats.
    Circulation research, 1988, Volume: 62, Issue:2

    Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Cardiomegaly; Heart Rate; Hypertens

1988
Effects of minoxidil on blood pressure and cardiac hypertrophy in two-kidney, one-clip hypertensive rats.
    Canadian journal of physiology and pharmacology, 1985, Volume: 63, Issue:2

    Topics: Animals; Blood Pressure; Body Weight; Cardiomegaly; Drinking; Hypertension, Renal; Male; Minoxidil;

1985
Minoxidil does not possess androgenic activity.
    Pharmacology, 1988, Volume: 36, Issue:5

    Topics: Androgens; Animals; Body Weight; Dihydrotestosterone; Male; Mice; Minoxidil; Orchiectomy; Organ Size

1988
[Kidney function in spontaneously hypertensive rats under minoxidil treatment].
    Biomedica biochimica acta, 1987, Volume: 46, Issue:6

    Topics: Animals; Blood Pressure; Body Weight; Diuresis; Electrolytes; Glomerular Filtration Rate; Heart Rate

1987
Effects of chronic administration of prostaglandin E1 (PGE1) on arterial blood pressure of unanesthetized hypertensive rats.
    Prostaglandins, 1974, Jul-10, Volume: 7, Issue:1

    Topics: Animals; Blood Pressure; Body Weight; Female; Hypertension; Hypertension, Renal; Kidney; Male; Minox

1974