Page last updated: 2024-10-31

minoxidil and Adverse Drug Event

minoxidil has been researched along with Adverse Drug Event in 12 studies

Minoxidil: A potent direct-acting peripheral vasodilator (VASODILATOR AGENTS) that reduces peripheral resistance and produces a fall in BLOOD PRESSURE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p371)
minoxidil : A pyrimidine N-oxide that is pyrimidine-2,4-diamine 3-oxide substituted by a piperidin-1-yl group at position 6.

Research Excerpts

ExcerptRelevanceReference
"Cetirizine is an antihistamine that may be effective in hair loss treatment."7.30Comparison between topical cetirizine with minoxidil versus topical placebo with minoxidil in female androgenetic alopecia: a randomized, double-blind, placebo-controlled study. ( Abbassi, MM; Bassiouny, EA; El-Samanoudy, SI; Farid, SF; Nada, HR, 2023)
"Recent studies are promising for the intradermal delivery of dutasteride and minoxidil in the treatment of androgenetic alopecia."4.31Intradermal Delivery of Alopecia Therapeutics: Current State and Future Prospects. ( Alhanshali, L; Buontempo, M; Lo Sicco, K; Majerson, D; Shapiro, J, 2023)
"Minoxidil (2,4-diamino-6-(piperidin-1'-yl)pyrimidine N(3)-oxide; CASRN 38304-91-5) is a bioactive molecule with several nitrosatable groups widely used as an antihypertensive and antialopecia agent."3.77Aromatic C-nitrosation of a bioactive molecule. Nitrosation of minoxidil. ( Arenas-Valgañón, J; Calle, E; Casado, J; González-Jiménez, M, 2011)
"Cetirizine is an antihistamine that may be effective in hair loss treatment."3.30Comparison between topical cetirizine with minoxidil versus topical placebo with minoxidil in female androgenetic alopecia: a randomized, double-blind, placebo-controlled study. ( Abbassi, MM; Bassiouny, EA; El-Samanoudy, SI; Farid, SF; Nada, HR, 2023)
" However, little is known about the differences in adverse effects between these two drugs."1.43Differences in reproductive toxicology between alopecia drugs: an analysis on adverse events among female and male cases. ( Li, Q; Wu, M; Yu, Q, 2016)
" We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts."1.37FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011)
"5 million adverse drug reaction (ADR) reports for 8620 drugs/biologics that are listed for 1191 Coding Symbols for Thesaurus of Adverse Reaction (COSTAR) terms of adverse effects."1.32Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. ( Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL, 2004)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's7 (58.33)24.3611
2020's4 (33.33)2.80

Authors

AuthorsStudies
Matthews, EJ1
Kruhlak, NL1
Weaver, JL1
Benz, RD1
Contrera, JF1
Chen, M1
Vijay, V1
Shi, Q2
Liu, Z2
Fang, H2
Tong, W2
Ding, D1
Kelly, R1
Sakatis, MZ1
Reese, MJ1
Harrell, AW1
Taylor, MA1
Baines, IA1
Chen, L1
Bloomer, JC1
Yang, EY1
Ellens, HM1
Ambroso, JL1
Lovatt, CA1
Ayrton, AD1
Clarke, SE1
Morgan, RE1
van Staden, CJ1
Chen, Y1
Kalyanaraman, N1
Kalanzi, J1
Dunn, RT1
Afshari, CA1
Hamadeh, HK1
Bassiouny, EA1
El-Samanoudy, SI1
Abbassi, MM1
Nada, HR1
Farid, SF1
Alhanshali, L1
Buontempo, M1
Majerson, D1
Shapiro, J1
Lo Sicco, K1
Legiawati, L1
Suseno, LS1
Sitohang, IBS1
Yusharyahya, SN1
Pawitan, JA1
Liem, IK1
Kurniawati, T1
Ardelia, A1
Paramastri, K1
Beach, RA1
McDonald, KA1
Barrett, BM1
Abdel-Qadir, H1
Wu, M1
Yu, Q1
Li, Q1
González-Jiménez, M1
Arenas-Valgañón, J1
Calle, E1
Casado, J1
Bergstrom, KG1

Trials

2 trials available for minoxidil and Adverse Drug Event

ArticleYear
Comparison between topical cetirizine with minoxidil versus topical placebo with minoxidil in female androgenetic alopecia: a randomized, double-blind, placebo-controlled study.
    Archives of dermatological research, 2023, Volume: 315, Issue:5

    Topics: Administration, Topical; Alopecia; Cetirizine; Drug-Related Side Effects and Adverse Reactions; Fema

2023
Combination of adipose-derived stem cell conditioned media and minoxidil for hair regrowth in male androgenetic alopecia: a randomized, double-blind clinical trial.
    Stem cell research & therapy, 2023, 08-21, Volume: 14, Issue:1

    Topics: Adipocytes; Alopecia; Culture Media, Conditioned; Drug-Related Side Effects and Adverse Reactions; H

2023

Other Studies

10 other studies available for minoxidil and Adverse Drug Event

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Dru

2004
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des

2011
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily

2013
Intradermal Delivery of Alopecia Therapeutics: Current State and Future Prospects.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2023, 09-01, Volume: 49, Issue:9

    Topics: Alopecia; Drug-Related Side Effects and Adverse Reactions; Dutasteride; Humans; Mesotherapy; Minoxid

2023
Side effects of low-dose oral minoxidil for treating alopecia.
    Journal of the American Academy of Dermatology, 2021, Volume: 84, Issue:5

    Topics: Administration, Oral; Alopecia; Drug-Related Side Effects and Adverse Reactions; Humans; Minoxidil

2021
Differences in reproductive toxicology between alopecia drugs: an analysis on adverse events among female and male cases.
    Oncotarget, 2016, Dec-13, Volume: 7, Issue:50

    Topics: 5-alpha Reductase Inhibitors; Adverse Drug Reaction Reporting Systems; Alopecia; Drug-Related Side E

2016
Aromatic C-nitrosation of a bioactive molecule. Nitrosation of minoxidil.
    Organic & biomolecular chemistry, 2011, Oct-26, Volume: 9, Issue:22

    Topics: Alopecia; Animals; Antihypertensive Agents; Chromatography, Liquid; Dimethylnitrosamine; Drug-Relate

2011
What's new in androgenetic alopecia: approvals, long-term safety data, cancer risk and treatment options for women.
    Journal of drugs in dermatology : JDD, 2011, Volume: 10, Issue:1

    Topics: Alopecia; Azasteroids; Drug Approval; Drug-Related Side Effects and Adverse Reactions; Dutasteride;

2011