minocycline and Tuberculoma

Mycobacterium marinum is an atypical mycobacterium that causes a skin infection known as fish tank granuloma or swimming pool granuloma affecting people who are exposed to aquatic environments. In general, it is managed medically with antimicrobials and variable treatment protocols. Here, we report a Saudi gentleman who acquired this infection in Thailand and was misdiagnosed as cutaneous leishmaniasis. After establishing the correct diagnosis, treatment with minocycline and trimethoprim-sulfamethoxazole resulted in rapid healing.

Topics: Adult; Animals; Anti-Bacterial Agents; Diagnosis, Differential; Diagnostic Errors; Drug Combinations; Fishes; Hobbies; Humans; Leishmaniasis, Cutaneous; Male; Minocycline; Mycobacterium Infections, Nontuberculous; Mycobacterium marinum; Sulfadiazine; Trimethoprim; Tuberculoma; Tuberculosis, Cutaneous

Granulomatous rosacea is a variant of rosacea that may present similar to other granulomatous diseases. We present the case of a 45-year-old woman with a 2-year history of facial erythema with multiple papules and pustules on the cheeks, chin, and glabella. The patient responded to minocycline, resulting in healing 6 months without residual scarring. This patient's clinical and histological presentation and treatment outcome are to our assessment consistent with granulomatous rosacea. However, other clinically and histologically related entities will be discussed. These entities include, but are not limited to, perioral dermatitis, granulomatous periorificial dermatitis, lupus miliaris disseminatus faciei, facial afro-caribbean eruption syndrome, and sarcoidosis.

Topics: Dermatitis, Perioral; Diagnosis, Differential; Facial Dermatoses; Female; Granuloma; Humans; Middle Aged; Minocycline; Remission Induction; Rosacea; Skin Diseases, Papulosquamous; Tuberculoma