minocycline and Lymphohistiocytosis--Hemophagocytic

Topics: Adult; Aged; Anemia, Hemolytic; Anti-Bacterial Agents; Female; Guillain-Barre Syndrome; Humans; Japan; Lymphohistiocytosis, Hemophagocytic; Male; Middle Aged; Minocycline; Mycoplasma pneumoniae; Pneumonia, Mycoplasma; Steroids; Stevens-Johnson Syndrome; Young Adult

Scrub typhus is associated with various clinical symptoms. However, the pathogenesis of scrub typhus infection remains to be elucidated. A 73-year-old man was admitted to our hospital with consciousness disturbance and suspected meningoencephalitis. The patient's laboratory data showed deterioration and were indicative of hemophagocytic lymphohistiocytosis (HLH). A whole body examination to detect the trigger disease revealed an eschar, which is a characteristic of scrub typhus, on his back. His symptoms showed dramatic improvement after the administration of minocycline (MINO). This case report highlights that the clinical course of a case of scrub typhus meningoencephalitis that was cured with MINO.

Topics: Aged; Diagnosis, Differential; Humans; Lymphohistiocytosis, Hemophagocytic; Male; Meningoencephalitis; Minocycline; Scrub Typhus

Topics: Aged; Animals; Bone Marrow; Diagnostic Errors; DNA, Bacterial; Dogs; Emergencies; Female; Humans; Infant; Lymphohistiocytosis, Hemophagocytic; Minocycline; Mucocutaneous Lymph Node Syndrome; Pets; Rickettsia; Rickettsia Infections

Chronic granulomatous disease (CGD) is a primary immunodeficiency characterized by recurrent infections with certain types of bacteria and fungi. Presented herein is the case of a 29 year old woman with CGD who suffered from bacteria-associated haemophagocytic syndrome and a septic pulmonary embolism following a uterine infection and sepsis, caused by Burkholderia cepacia complex.

Topics: Adult; Anti-Bacterial Agents; Antifungal Agents; Burkholderia cepacia complex; Burkholderia Infections; Echinocandins; Female; Granulomatous Disease, Chronic; Humans; Lipopeptides; Lipoproteins; Lymphohistiocytosis, Hemophagocytic; Micafungin; Minocycline; Peptides, Cyclic; Pulmonary Embolism; Sepsis; Trimethoprim, Sulfamethoxazole Drug Combination

Topics: Aged; Anti-Bacterial Agents; Female; Genitalia, Female; Humans; Lymphohistiocytosis, Hemophagocytic; Minocycline; Parvoviridae Infections; Parvovirus B19, Human; Scrub Typhus; Treatment Outcome