minocycline and Leg-Ulcer

Topics: Adult; Aged; Anti-Bacterial Agents; Female; Humans; Leg Ulcer; Minocycline; Pyoderma Gangrenosum; Treatment Outcome

We describe an immunocompromised patient with disseminated Legionella pneumophila infection. A chronic leg ulcer was probably the port of entry for the infection. Treatment required several operations and prolonged antimicrobial treatment. To our knowledge, this is the first case report of Legionella soft tissue infection and pneumonia treated with tigecycline.

Topics: Anti-Bacterial Agents; Humans; Immunocompromised Host; Leg Ulcer; Legionella pneumophila; Legionnaires' Disease; Male; Middle Aged; Minocycline; Pneumonia; Soft Tissue Infections; Tigecycline

Topics: Anti-Bacterial Agents; Diabetes Mellitus, Type 1; Humans; Hyperpigmentation; Leg Ulcer; Male; Middle Aged; Minocycline; Prognosis; Staphylococcal Infections

Induration of the lower parts of the legs with abscess and ulcer formation occurred in a 60-year-old woman. Mycobacterium chelonei, a ubiquitous, saprophytic pathogen that uncommonly causes human disease, was cultured from biopsy material. Although spontaneous healing usually occurs in a few months with such infections, our patient's disease persisted for more than two years until control was achieved with minocycline hydrochloride.

Topics: Abscess; Female; Humans; Leg Ulcer; Middle Aged; Minocycline; Mycobacterium; Mycobacterium Infections; Skin Diseases, Infectious