minocycline and Foot-Diseases

A 16-year-old boy developed left foot pain of unknown cause that was unresponsive to conservative treatment, associated with fever and difficulty walking. He was admitted to our hospital with osteomyelitis of the accessory and body of the navicular bone. Surgery could not be performed because the patient had been diagnosed with Wiskott-Aldrich syndrome. After antibiotic therapy, laboratory abnormalities and pain had resolved. One year after treatment, the patient had returned to his original level of sports activity. Both an accessory navicular and the body of the navicular bone may develop osteomyelitis in immunocompromised patients; early diagnosis is important for prescribing effective conservative treatment.

Topics: Administration, Intravenous; Adolescent; Anti-Bacterial Agents; Clindamycin; Diagnosis, Differential; Foot; Foot Diseases; Humans; Immunocompromised Host; Magnetic Resonance Imaging; Male; Minocycline; Osteomyelitis; Pain; Physical Therapy Modalities; Tarsal Bones; Treatment Outcome; Wiskott-Aldrich Syndrome

Topics: Abnormalities, Severe Teratoid; Central Nervous System Diseases; Communicable Diseases; Congenital Abnormalities; Diseases in Twins; Female; Foot Diseases; Hand Deformities; Humans; Infant; Infant, Newborn; Minocycline; Pregnancy; Pregnancy Complications, Infectious; Rubella