minocycline and Exostoses

Minocycline hydrochloride, an analog of tetracycline, is widely used in the treatment of acne. Its use has been associated with discoloration of teeth, bone, and other tissues.. A case is presented involving a patient with minocycline-induced staining of the torus palatinus and alveolar bone.. No treatment was rendered since the patient was not concerned with the appearance of the discoloration. The patient's dermatologist elected to change antibiotics.. Patients on long-term minocycline therapy should be made aware of the possibility of pigmentation of bone and soft tissue that may be reversible with discontinuation of therapy; however, minocycline-induced staining of the permanent dentition may not be reversible.

Topics: Acne Vulgaris; Adult; Alveolar Process; Anti-Bacterial Agents; Exostoses; Female; Humans; Maxillary Diseases; Minocycline; Palate; Pigmentation Disorders