minocycline has been researched along with Cholestasis--Intrahepatic* in 2 studies
2 other study(ies) available for minocycline and Cholestasis--Intrahepatic
Article | Year |
---|---|
Acute intrahepatic cholestasis accompanied with Chlamydophila pneumoniae infection.
We report a case of Chlamydophila (C.) pneumoniae infection presenting with fever and rapid intrahepatic cholestasis. A 63-year-old man had a week-long history of intermittent high fever and rapidly progressive jaundice with atypical erythema. The results of liver function tests were recorded. The results of all serological tests were negative; the IgM, IgG, and IgA titers for C. pneumoniae had increased, which indicates a C. pneumoniae infection. The patient's fever and liver dysfunction improved upon administration of minocycline. Light microscopic findings showed the presence of enlarged liver cells with clear cytoplasm, a few mitotic figures, multinucleated cells, and bile cholestasis. The electron microscopic appearance of liver biopsy showed that bile canaliculi exhibited intrahepatic forms of cholestasis. From the results of light and electron microscopy, we inferred atypical intrahepatic cholestasis, probably resulting from the C. pneumoniae infection. Topics: Alanine Transaminase; Anti-Bacterial Agents; Antibodies, Bacterial; Aspartate Aminotransferases; Chlamydophila Infections; Chlamydophila pneumoniae; Cholestasis, Intrahepatic; Erythema Nodosum; Fever; Humans; Jaundice, Obstructive; Liver; Lung; Male; Middle Aged; Minocycline | 2011 |
Obstructive jaundice caused by non-parasitic hepatic cyst treated with percutaneous drainage and instillation of minocycline hydrochloride as a sclerosing agent.
We report a case of obstructive jaundice caused by a large hepatic cyst which was successfully treated by percutaneous drainage and instillation of minocycline hydrochloride. An 88-year-old man presented with obstructive jaundice and upper abdominal fullness. Abdominal CT and ultrasonography revealed a large hepatic cyst and intrahepatic bile duct dilatation. After the percutaneous drainage of the cyst, minocycline hydrochloride was instilled as a sclerosant via a catheter into the cyst cavity. Liver enzyme levels returned to normal and the jaundice disappeared. Nine months after the treatment, the large cyst and dilatation of the intrahepatic bile duct had disappeared. The patient has remained healthy without symptoms. Topics: Aged; Aged, 80 and over; Cholestasis, Intrahepatic; Cysts; Drainage; Humans; Instillation, Drug; Liver Diseases; Male; Minocycline; Sclerosing Solutions; Sclerotherapy; Tomography, X-Ray Computed; Ultrasonography | 1996 |