minocycline and Cholecystitis--Acute

Raoultella planticola has been considered a relatively harmless Gram-negative bacteria, rarely associated with clinical infection. However, in recent years, the frequency at which severe infection by R. planticola and drug-resistant strains are reported in literature has increased. Here, we present one case of acute cholecystitis caused by R. planticola, and review all previously reported cases of the infection in an attempt to identify new trends in biological and clinical features of R. planticola infections.

Topics: Abdominal Pain; Aged; Aged, 80 and over; Alcoholism; Anti-Bacterial Agents; Cholecystitis, Acute; Communicable Diseases, Emerging; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Humans; Male; Middle Aged; Minocycline; Tigecycline

An 81-year-old female experiencing high fever, fatigue, and loss of appetite was admitted to our hospital and diagnosed with acute cholecystitis. Her condition did not improve and an eschar and erythema subsequently appeared. We then diagnosed Japanese spotted fever (JSF). She recovered immediately after the administration of minocycline. This case differed from other cases because the patient had a remarkably acute hepatic failure.. Considering that the present case might be associated with other factors, we performed a repeat polymerase chain reaction (PCR) test on the patient's blood that had been collected on admission and stored.. Epstein-Barr virus (EBV) was detected in her blood by PCR.. We consider this case might be associated with EBV.

Topics: Aged, 80 and over; Anti-Bacterial Agents; Cefoperazone; Cholecystitis, Acute; Epstein-Barr Virus Infections; Female; Herpesvirus 4, Human; Humans; Liver Failure, Acute; Minocycline; Polymerase Chain Reaction; Rickettsia; Rickettsia Infections; Sulbactam