minocycline and Bronchopulmonary-Dysplasia

Mycobacterium abscessus complex and other non-tuberculous mycobacteria are infrequently encountered respiratory pathogens in patients with tracheostomies. We report a 4-year-old girl with a tracheostomy, placed during infancy for management of severe bronchopulmonary dysplasia and laryngeal stenosis, who developed a M. abscessus complex lung infection. There was clear evidence of parenchymal involvement and true infection beyond colonization. She demonstrated dramatic clinical, laboratory, and radiographic improvement after prolonged anti-mycobacterial therapy.

Topics: Amikacin; Anti-Bacterial Agents; Bronchopulmonary Dysplasia; Child, Preschool; Clarithromycin; Female; Humans; Laryngostenosis; Minocycline; Mycobacterium Infections, Nontuberculous; Tigecycline; Tomography, X-Ray Computed; Tracheostomy; Tuberculosis, Pulmonary