minocycline and Bronchial-Diseases

Topics: Adult; Aged; Ampicillin; Bacterial Infections; Bronchial Diseases; Clinical Trials as Topic; Doxycycline; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Minocycline; Tetracyclines

Topics: Anti-Bacterial Agents; Bronchial Diseases; Bronchoscopy; Clarithromycin; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Middle Aged; Minocycline; Radiography; Sarcoidosis; Time Factors; Treatment Outcome

A 62-year-old woman was admitted with fever and bloody sputum. A mass shadow in the left S3 and obstruction of the left B3 were seen on a chest radiograph and CT. Obstructive pneumonia was suspected, and cefotiam and imipenem/cilastatin were administered. However, this treatment did not show adequate efficacy. Bronchoscopy demonstrated a yellowish-white polypoid lesion in the left B3, but histopathological findings with HE staining yielded no definite diagnosis. Subsequently, Nocardia asteroides was detected in sputum test. A sulfamethoxazole-trimethoprim combination and minocycline were administered, and the clinical findings improved. Gram-positive microfilaments were confirmed retrospectively in the pathologic specimen, and a diagnosis of pulmonary nocardiosis was made.

Topics: Anti-Bacterial Agents; Bronchial Diseases; Female; Humans; Lung Diseases; Middle Aged; Minocycline; Nocardia asteroides; Nocardia Infections; Polyps; Trimethoprim, Sulfamethoxazole Drug Combination

Topics: Bronchi; Bronchial Diseases; Humans; Minocycline; Tetracyclines

Topics: Aged; Albumins; Bronchial Diseases; Female; Humans; Lung Diseases; Male; Middle Aged; Minocycline; Oxytetracycline; Respiratory Tract Infections; Sputum; Tetracyclines; Time Factors; Transferrin