minocycline and Anemia--Hemolytic

Topics: Adult; Aged; Anemia, Hemolytic; Anti-Bacterial Agents; Female; Guillain-Barre Syndrome; Humans; Japan; Lymphohistiocytosis, Hemophagocytic; Male; Middle Aged; Minocycline; Mycoplasma pneumoniae; Pneumonia, Mycoplasma; Steroids; Stevens-Johnson Syndrome; Young Adult

A 32-year-old patient taking corticosteroid therapy for 10 months for autoimmune hemolytic anemia developed Hodgkin's disease and concomitant acute pulmonary nocardiosis. After treatment with imipenen and amikacin for 15 days, which was adapted to susceptibility tests, multiple-drug chemotherapy using the ABVD protocol (doxorubicin, bléomycin, vinblastine, dacarbazine) was given without recurrence of the pulmonary infection. Antibiotic prophylaxis using a minocycine-erythromycin combination was continued for 8 months. We discuss the importance of long-term treatment based on data in the literature.

Topics: Adult; Amikacin; Anemia, Hemolytic; Antineoplastic Combined Chemotherapy Protocols; Drug Therapy, Combination; Erythromycin; Hodgkin Disease; Humans; Imipenem; Long-Term Care; Lung Diseases; Male; Minocycline; Nocardia Infections

Topics: Administration, Oral; Anemia, Hemolytic; Blood-Brain Barrier; Chlortetracycline; Demeclocycline; Doxycycline; Drug Hypersensitivity; Female; Glucosephosphate Dehydrogenase Deficiency; Gonorrhea; Humans; Injections, Intramuscular; Intestinal Absorption; Male; Methacycline; Minocycline; Oxytetracycline; Penicillins; Tetracycline; Urethritis