minaprine has been researched along with Brain Ischemia in 6 studies
minaprine: Agr 1240 refers to di-HCl; short-acting type A MAO inhibitor (MAOI) of mild potency; structure
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Effect of minaprine on hypoxia- or hypoxia/hypoglycemia (ischemia)-induced impairment of 2-deoxyglucose (2DG) uptake by rat hippocampal slices was evaluated." | 7.68 | Protective effect of minaprine against the abnormal changes of 2-deoxyglucose uptake by rat hippocampal slices induced by hypoxia/hypoglycemia. ( Kodama, K; Shibata, S; Ueki, S, 1992) |
| "We examined the characteristics of cerebral ischemia-induced behavioral deficit in the passive avoidance task and the effect of minaprine and other cytoprotective drugs on passive avoidance deficit induced by cerebral ischemia in Mongolian gerbils." | 7.68 | Effect of minaprine and other reference drugs on passive avoidance impairment induced by cerebral ischemia in Mongolian gerbils. ( Aihara, H; Araki, H; Karasawa, Y; Okuyama, S; Otomo, S, 1990) |
| "Using a repeated acquisition procedure in a three-panel runway apparatus, the effects of minaprine on the impairment of working memory produced by scopolamine, ethylcholine aziridinium ion (AF64A) or cerebral ischemia were investigated in rats." | 7.68 | Minaprine improves impairment of working memory induced by scopolamine and cerebral ischemia in rats. ( Furuya, Y; Kitajima, I; Ohno, M; Ueki, S; Yamamoto, T; Yatsugi, S, 1990) |
| "Effect of minaprine on hypoxia- or hypoxia/hypoglycemia (ischemia)-induced impairment of 2-deoxyglucose (2DG) uptake by rat hippocampal slices was evaluated." | 3.68 | Protective effect of minaprine against the abnormal changes of 2-deoxyglucose uptake by rat hippocampal slices induced by hypoxia/hypoglycemia. ( Kodama, K; Shibata, S; Ueki, S, 1992) |
| "We examined the characteristics of cerebral ischemia-induced behavioral deficit in the passive avoidance task and the effect of minaprine and other cytoprotective drugs on passive avoidance deficit induced by cerebral ischemia in Mongolian gerbils." | 3.68 | Effect of minaprine and other reference drugs on passive avoidance impairment induced by cerebral ischemia in Mongolian gerbils. ( Aihara, H; Araki, H; Karasawa, Y; Okuyama, S; Otomo, S, 1990) |
| "Using a repeated acquisition procedure in a three-panel runway apparatus, the effects of minaprine on the impairment of working memory produced by scopolamine, ethylcholine aziridinium ion (AF64A) or cerebral ischemia were investigated in rats." | 3.68 | Minaprine improves impairment of working memory induced by scopolamine and cerebral ischemia in rats. ( Furuya, Y; Kitajima, I; Ohno, M; Ueki, S; Yamamoto, T; Yatsugi, S, 1990) |
| "The effect of the psychotropic drug minaprine on brain ischemia induced by a 5-min bilateral occlusion of the carotid arteries in the mongolian gerbil was studied." | 3.67 | Effect of minaprine on "delayed neuronal death" in mongolian gerbils with occluded common carotid arteries. ( Aihara, H; Araki, H; Kimura, M; Nojiri, M, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Piao, Y | 1 |
| Mineshita, S | 1 |
| Kuroiwa, T | 1 |
| Koike, Y | 1 |
| Kodama, K | 1 |
| Shibata, S | 1 |
| Ueki, S | 2 |
| Karasawa, Y | 2 |
| Araki, H | 3 |
| Okuyama, S | 2 |
| Aihara, H | 3 |
| Otomo, S | 1 |
| Yamamoto, T | 1 |
| Yatsugi, S | 1 |
| Ohno, M | 1 |
| Furuya, Y | 1 |
| Kitajima, I | 1 |
| Shiratsuchi, A | 1 |
| Nojiri, M | 1 |
| Kimura, M | 1 |
6 other studies available for minaprine and Brain Ischemia
| Article | Year |
|---|---|
Prevention by minaprine of ischemic neuronal damage and memory impairment in Mongolian gerbils.
Topics: Animals; Brain Ischemia; Female; Gerbillinae; Hippocampus; Male; Memory Disorders; Neurons; Phrenic | 1995 |
Protective effect of minaprine against the abnormal changes of 2-deoxyglucose uptake by rat hippocampal slices induced by hypoxia/hypoglycemia.
Topics: Acetylcholine; Animals; Brain Ischemia; Central Nervous System Stimulants; Deoxyglucose; Hippocampus | 1992 |
Effect of minaprine and other reference drugs on passive avoidance impairment induced by cerebral ischemia in Mongolian gerbils.
Topics: Animals; Avoidance Learning; Brain Ischemia; Carotid Arteries; Central Nervous System Stimulants; Ge | 1990 |
Minaprine improves impairment of working memory induced by scopolamine and cerebral ischemia in rats.
Topics: Animals; Aziridines; Benzoquinones; Brain Ischemia; Choline; Hippocampus; Injections; Male; Memory; | 1990 |
Protective effects of minaprine on the cerebrum of rodents.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Brain Ischemia; Hypoxia; Male; Mice; Mice, Inb | 1988 |
Effect of minaprine on "delayed neuronal death" in mongolian gerbils with occluded common carotid arteries.
Topics: Animals; Arterial Occlusive Diseases; Avoidance Learning; Brain Ischemia; Carotid Artery Diseases; C | 1987 |