minaprine has been researched along with ALS - Amyotrophic Lateral Sclerosis in 1 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amante, D; Benmohamed, R; Chen, T; Ferrante, RJ; Kim, J; Kirsch, DR; Morimoto, RI; Silverman, RB; Smith, K | 1 |
1 other study(ies) available for minaprine and ALS - Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
ADME-guided design and synthesis of aryloxanyl pyrazolone derivatives to block mutant superoxide dismutase 1 (SOD1) cytotoxicity and protein aggregation: potential application for the treatment of amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Blood-Brain Barrier; Caco-2 Cells; Cell Membrane Permeability; Cytochrome P-450 Enzyme Inhibitors; Drug Design; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Ethers; HEK293 Cells; Humans; In Vitro Techniques; Mice; Microsomes, Liver; Mutation; Neurons; Pyrazoles; Pyrazolones; Rats; Rats, Sprague-Dawley; Solubility; Structure-Activity Relationship; Sulfones; Superoxide Dismutase; Superoxide Dismutase-1 | 2012 |