mimosine has been researched along with Melanoma in 3 studies
Mimosine: 3-Hydroxy-4-oxo-1(4H)-pyridinealanine. An antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The anticancer activity of a series of novel synthesized, hydroxypyridone-based metal chelators (analogues of L-mimosine) was evaluated in an in vitro model of melanoma consisting of malignant melanoma (A375), non-melanoma epidermoid carcinoma (A431) and immortalized non-malignant keratinocyte (HaCaT) cells." | 7.96 | Anticancer activity of a novel methylated analogue of L-mimosine against an in vitro model of human malignant melanoma. ( Cheung, W; Kyriakou, S; Mantso, T; Mitsiogianni, M; Panayiotidis, MI; Pappa, A; Tetard, D; Todryk, S; Veuger, S, 2020) |
| "Melanoma is an aggressive and highly metastatic type of skin cancer where the design of new therapies is of utmost importance for the clinical management of the disease." | 5.62 | A novel methylated analogue of L-Mimosine exerts its therapeutic potency through ROS production and ceramide-induced apoptosis in malignant melanoma. ( Anestopoulos, I; Cheung, W; Franco, R; Kyriakou, S; Mantso, T; Mitsiogianni, M; Panayiotidis, MI; Pappa, A; Tetard, D; Trafalis, DT; Veuger, S, 2021) |
| "The anticancer activity of a series of novel synthesized, hydroxypyridone-based metal chelators (analogues of L-mimosine) was evaluated in an in vitro model of melanoma consisting of malignant melanoma (A375), non-melanoma epidermoid carcinoma (A431) and immortalized non-malignant keratinocyte (HaCaT) cells." | 3.96 | Anticancer activity of a novel methylated analogue of L-mimosine against an in vitro model of human malignant melanoma. ( Cheung, W; Kyriakou, S; Mantso, T; Mitsiogianni, M; Panayiotidis, MI; Pappa, A; Tetard, D; Todryk, S; Veuger, S, 2020) |
| "Melanoma is an aggressive and highly metastatic type of skin cancer where the design of new therapies is of utmost importance for the clinical management of the disease." | 1.62 | A novel methylated analogue of L-Mimosine exerts its therapeutic potency through ROS production and ceramide-induced apoptosis in malignant melanoma. ( Anestopoulos, I; Cheung, W; Franco, R; Kyriakou, S; Mantso, T; Mitsiogianni, M; Panayiotidis, MI; Pappa, A; Tetard, D; Trafalis, DT; Veuger, S, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Kyriakou, S | 2 |
| Cheung, W | 2 |
| Mantso, T | 2 |
| Mitsiogianni, M | 2 |
| Anestopoulos, I | 1 |
| Veuger, S | 2 |
| Trafalis, DT | 1 |
| Franco, R | 1 |
| Pappa, A | 2 |
| Tetard, D | 2 |
| Panayiotidis, MI | 2 |
| Todryk, S | 1 |
| Hashiguchi, H | 1 |
| Takahashi, H | 1 |
3 other studies available for mimosine and Melanoma
| Article | Year |
|---|---|
A novel methylated analogue of L-Mimosine exerts its therapeutic potency through ROS production and ceramide-induced apoptosis in malignant melanoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Ceramides; Flow Cytometry; Humans; Mela | 2021 |
Anticancer activity of a novel methylated analogue of L-mimosine against an in vitro model of human malignant melanoma.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Cycle Checkpoints; Cell Line; Cell | 2020 |
Inhibition of two copper-containing enzymes, tyrosinase and dopamine beta-hydroxylase, by L-mimosine.
Topics: Adrenal Medulla; Animals; Catechol Oxidase; Cattle; Copper; Dopamine beta-Hydroxylase; Drug Interact | 1977 |