mimosine has been researched along with Breast Cancer in 4 studies
Mimosine: 3-Hydroxy-4-oxo-1(4H)-pyridinealanine. An antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mimosine is a toxic nonprotein amino acid that is a major constituent of the tropical legumes Leucaena and Mimosa." | 5.29 | Mimosine blocks cell cycle progression by chelating iron in asynchronous human breast cancer cells. ( Kulp, KS; Vulliet, PR, 1996) |
| "Mimosine is a toxic nonprotein amino acid that is a major constituent of the tropical legumes Leucaena and Mimosa." | 1.29 | Mimosine blocks cell cycle progression by chelating iron in asynchronous human breast cancer cells. ( Kulp, KS; Vulliet, PR, 1996) |
| "Mimosine is a potent reversible late G1 phase blocker of the cell cycle." | 1.29 | p21WAF1/CIP1/SDI1 is elevated through a p53-independent pathway by mimosine. ( Alpan, RS; Pardee, AB, 1996) |
| "Treating breast cancer cells with 400 microM mimosine for 24 h inhibited cyclin E- and cyclin A-associated kinase activity by 85% or more, although immunoblots using anti-cyclin A, cyclin E, cdc2, and cdk2 antibodies showed that these key subunits were still present in the cells at pretreatment levels." | 1.29 | Iron deprivation inhibits cyclin-dependent kinase activity and decreases cyclin D/CDK4 protein levels in asynchronous MDA-MB-453 human breast cancer cells. ( Green, SL; Kulp, KS; Vulliet, PR, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iglesias, P | 1 |
| Penas, C | 1 |
| Barral-Cagiao, L | 1 |
| Pazos, E | 1 |
| Costoya, JA | 1 |
| Kulp, KS | 2 |
| Vulliet, PR | 2 |
| Alpan, RS | 1 |
| Pardee, AB | 1 |
| Green, SL | 1 |
4 other studies available for mimosine and Breast Cancer
| Article | Year |
|---|---|
A Bio-inspired Hypoxia Sensor using HIF1a-Oxygen-Dependent Degradation Domain.
Topics: Animals; Biosensing Techniques; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cobalt; Female; Fl | 2019 |
Mimosine blocks cell cycle progression by chelating iron in asynchronous human breast cancer cells.
Topics: Breast Neoplasms; Cell Cycle; Cell Division; Cell Survival; Deferoxamine; DNA, Neoplasm; Dose-Respon | 1996 |
p21WAF1/CIP1/SDI1 is elevated through a p53-independent pathway by mimosine.
Topics: Breast Neoplasms; Cell Cycle; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Female; Humans; Mimosi | 1996 |
Iron deprivation inhibits cyclin-dependent kinase activity and decreases cyclin D/CDK4 protein levels in asynchronous MDA-MB-453 human breast cancer cells.
Topics: Breast Neoplasms; Cell Cycle; Cell Division; Cell Line; Cyclin D; Cyclin-Dependent Kinase 4; Cyclin- | 1996 |