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mimosine and Ataxia Telangiectasia

mimosine has been researched along with Ataxia Telangiectasia in 1 studies

Mimosine: 3-Hydroxy-4-oxo-1(4H)-pyridinealanine. An antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca.

Ataxia Telangiectasia: An autosomal recessive inherited disorder characterized by choreoathetosis beginning in childhood, progressive CEREBELLAR ATAXIA; TELANGIECTASIS of CONJUNCTIVA and SKIN; DYSARTHRIA; B- and T-cell immunodeficiency, and RADIOSENSITIVITY to IONIZING RADIATION. Affected individuals are prone to recurrent sinobronchopulmonary infections, lymphoreticular neoplasms, and other malignancies. Serum ALPHA-FETOPROTEINS are usually elevated. (Menkes, Textbook of Child Neurology, 5th ed, p688) The gene for this disorder (ATM) encodes a cell cycle checkpoint protein kinase and has been mapped to chromosome 11 (11q22-q23).

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Khanna, KK1
Lavin, MF1

Other Studies

1 other study available for mimosine and Ataxia Telangiectasia

ArticleYear
Ionizing radiation and UV induction of p53 protein by different pathways in ataxia-telangiectasia cells.
    Oncogene, 1993, Volume: 8, Issue:12

    Topics: Aphidicolin; Ataxia Telangiectasia; Cell Cycle; Cell Line, Transformed; DNA Damage; Gene Expression

1993