miltefosine has been researched along with Trypanosomiasis in 4 studies
miltefosine: hexadecyl phosphocholine derivative of cisplatin; did not substantially activate HIV long terminal repeat; less toxic than cisplatin
miltefosine : A phospholipid that is the hexadecyl monoester of phosphocholine.
Trypanosomiasis: Infection with protozoa of the genus TRYPANOSOMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, a new semi-synthetic berberine analogue, 5,6-didehydro-8,8-diethyl-13-oxodihydroberberine chloride (1), showed nanomolar level potency against in vitro models of leishmaniasis, malaria, and trypanosomiasis as well as activity in an in vivo visceral leishmaniasis model." | 3.77 | Potent antiprotozoal activity of a novel semi-synthetic berberine derivative. ( Anklin, C; Bahar, M; Deng, Y; Doskotch, RW; Drew, ME; Gil, RR; He, S; Kinghorn, AD; Navarro-Vázquez, A; Pandharkar, T; Werbovetz, KA; Zhu, X, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Holloway, GA | 1 |
| Charman, WN | 1 |
| Fairlamb, AH | 1 |
| Brun, R | 1 |
| Kaiser, M | 1 |
| Kostewicz, E | 1 |
| Novello, PM | 1 |
| Parisot, JP | 1 |
| Richardson, J | 1 |
| Street, IP | 1 |
| Watson, KG | 1 |
| Baell, JB | 1 |
| Bahar, M | 1 |
| Deng, Y | 1 |
| Zhu, X | 1 |
| He, S | 1 |
| Pandharkar, T | 1 |
| Drew, ME | 1 |
| Navarro-Vázquez, A | 1 |
| Anklin, C | 1 |
| Gil, RR | 1 |
| Doskotch, RW | 1 |
| Werbovetz, KA | 1 |
| Kinghorn, AD | 1 |
| Bosc, D | 1 |
| Mouray, E | 1 |
| Cojean, S | 1 |
| Franco, CH | 1 |
| Loiseau, PM | 1 |
| Freitas-Junior, LH | 1 |
| Moraes, CB | 2 |
| Grellier, P | 1 |
| Dubois, J | 1 |
| Linciano, P | 1 |
| Pozzi, C | 1 |
| Iacono, LD | 1 |
| di Pisa, F | 1 |
| Landi, G | 1 |
| Bonucci, A | 1 |
| Gul, S | 1 |
| Kuzikov, M | 1 |
| Ellinger, B | 1 |
| Witt, G | 1 |
| Santarem, N | 1 |
| Baptista, C | 1 |
| Franco, C | 1 |
| Müller, W | 1 |
| Wittig, U | 1 |
| Luciani, R | 1 |
| Sesenna, A | 1 |
| Quotadamo, A | 1 |
| Ferrari, S | 1 |
| Pöhner, I | 1 |
| Cordeiro-da-Silva, A | 1 |
| Mangani, S | 1 |
| Costantino, L | 1 |
| Costi, MP | 1 |
4 other studies available for miltefosine and Trypanosomiasis
| Article | Year |
|---|---|
Trypanothione reductase high-throughput screening campaign identifies novel classes of inhibitors with antiparasitic activity.
Topics: Animals; Antiparasitic Agents; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Molecular St | 2009 |
Potent antiprotozoal activity of a novel semi-synthetic berberine derivative.
Topics: Animals; Antiprotozoal Agents; Berberine; Chlorocebus aethiops; Disease Models, Animal; Inhibitory C | 2011 |
Highly improved antiparasitic activity after introduction of an N-benzylimidazole moiety on protein farnesyltransferase inhibitors.
Topics: Alkyl and Aryl Transferases; Animals; Antiparasitic Agents; Cell Line; Enzyme Inhibitors; Humans; Im | 2016 |
Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections.
Topics: Animals; Antiprotozoal Agents; Benzothiazoles; Binding Sites; Catalytic Domain; Crystallography, X-R | 2019 |