miltefosine has been researched along with Renal Insufficiency in 2 studies
miltefosine: hexadecyl phosphocholine derivative of cisplatin; did not substantially activate HIV long terminal repeat; less toxic than cisplatin
miltefosine : A phospholipid that is the hexadecyl monoester of phosphocholine.
Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "There is still no effective treatment for cryptosporidiosis even though the disease has a significant impact on HIV-infected adults and children." | 6.76 | In a trial of the use of miltefosine to treat HIV-related cryptosporidiosis in Zambian adults, extreme metabolic disturbances contribute to high mortality. ( Katubulushi, M; Kelly, P; Obwaller, A; Sianongo, S; Sinkala, E, 2011) |
| "There is still no effective treatment for cryptosporidiosis even though the disease has a significant impact on HIV-infected adults and children." | 2.76 | In a trial of the use of miltefosine to treat HIV-related cryptosporidiosis in Zambian adults, extreme metabolic disturbances contribute to high mortality. ( Katubulushi, M; Kelly, P; Obwaller, A; Sianongo, S; Sinkala, E, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sinkala, E | 1 |
| Katubulushi, M | 1 |
| Sianongo, S | 1 |
| Obwaller, A | 1 |
| Kelly, P | 1 |
| Kumar, N | 1 |
| Pandey, K | 1 |
| Das, VN | 1 |
| Sinha, PK | 1 |
| Topno, RK | 1 |
| Verma, N | 1 |
| Lal, CS | 1 |
| Das, P | 1 |
| Bhattacharya, SK | 1 |
1 trial available for miltefosine and Renal Insufficiency
| Article | Year |
|---|---|
In a trial of the use of miltefosine to treat HIV-related cryptosporidiosis in Zambian adults, extreme metabolic disturbances contribute to high mortality.
Topics: Adult; AIDS-Related Opportunistic Infections; Cryptosporidiosis; Diarrhea; Early Termination of Clin | 2011 |
1 other study available for miltefosine and Renal Insufficiency
| Article | Year |
|---|---|
Miltefosine in the treatment of a case of visceral leishmaniasis with renal dysfunction.
Topics: Administration, Oral; Antiprotozoal Agents; Humans; India; Leishmaniasis, Visceral; Male; Middle Age | 2007 |