Page last updated: 2024-10-28

miltefosine and Pythiosis

miltefosine has been researched along with Pythiosis in 3 studies

miltefosine: hexadecyl phosphocholine derivative of cisplatin; did not substantially activate HIV long terminal repeat; less toxic than cisplatin
miltefosine : A phospholipid that is the hexadecyl monoester of phosphocholine.

Pythiosis: A granulomatous disease caused by the aquatic organism PYTHIUM insidiosum and occurring primarily in horses, cattle, dogs, cats, fishes, and rarely in humans. It is classified into three forms: ocular, cutaneous, and arterial.

Research Excerpts

ExcerptRelevanceReference
"We evaluated the efficacy of azithromycin (50 mg/kg, every 12 h [q12h] orally) and miltefosine (25 mg/kg, q24h orally) treatments in an experimental model of vascular/disseminated pythiosis in immunosuppressed mice."7.91Efficacy of Azithromycin and Miltefosine in Experimental Systemic Pythiosis in Immunosuppressed Mice. ( Alves, SH; de Azevedo, MI; de Jesus, FPK; Kommers, GD; Loreto, ES; Santurio, JM; Tondolo, JSM; Verdi, CM; Weiblen, C; Zanette, RA, 2019)
"The treatment with miltefosine demonstrated significantly lower subcutaneous lesion areas compared to the control group but was not sufficient for the complete remission of the lesions."5.56Efficacy of miltefosine therapy against subcutaneous experimental pythiosis in rabbits. ( Alves, SH; de Andrade, CM; de Jesus, FPK; Engelmann, AM; Kommers, GD; Loreto, ES; Santurio, JM; Silva, TM; Tondolo, JSM; Zanette, RA, 2020)
"We evaluated the efficacy of azithromycin (50 mg/kg, every 12 h [q12h] orally) and miltefosine (25 mg/kg, q24h orally) treatments in an experimental model of vascular/disseminated pythiosis in immunosuppressed mice."3.91Efficacy of Azithromycin and Miltefosine in Experimental Systemic Pythiosis in Immunosuppressed Mice. ( Alves, SH; de Azevedo, MI; de Jesus, FPK; Kommers, GD; Loreto, ES; Santurio, JM; Tondolo, JSM; Verdi, CM; Weiblen, C; Zanette, RA, 2019)
"The treatment with miltefosine demonstrated significantly lower subcutaneous lesion areas compared to the control group but was not sufficient for the complete remission of the lesions."1.56Efficacy of miltefosine therapy against subcutaneous experimental pythiosis in rabbits. ( Alves, SH; de Andrade, CM; de Jesus, FPK; Engelmann, AM; Kommers, GD; Loreto, ES; Santurio, JM; Silva, TM; Tondolo, JSM; Zanette, RA, 2020)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Loreto, ES3
Tondolo, JSM3
de Jesus, FPK2
Engelmann, AM1
de Andrade, CM1
Santurio, JM3
Zanette, RA2
Kommers, GD2
Silva, TM1
Alves, SH3
Oliveira, DC1
Verdi, CM1
Weiblen, C1
de Azevedo, MI1

Other Studies

3 other studies available for miltefosine and Pythiosis

ArticleYear
Efficacy of miltefosine therapy against subcutaneous experimental pythiosis in rabbits.
    Journal de mycologie medicale, 2020, Volume: 30, Issue:1

    Topics: Animals; Antifungal Agents; Dermatomycoses; Disease Models, Animal; Disease Progression; Dose-Respon

2020
    Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Azithromycin; Bridged Bicyclo Compounds, Heterocyclic; Clarithromyci

2018
Efficacy of Azithromycin and Miltefosine in Experimental Systemic Pythiosis in Immunosuppressed Mice.
    Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:1

    Topics: Animals; Antiprotozoal Agents; Azithromycin; Immunocompromised Host; Mice; Phosphorylcholine; Pythio

2019