miltefosine has been researched along with Parasitemia in 7 studies
miltefosine: hexadecyl phosphocholine derivative of cisplatin; did not substantially activate HIV long terminal repeat; less toxic than cisplatin
miltefosine : A phospholipid that is the hexadecyl monoester of phosphocholine.
Parasitemia: The presence of parasites (especially malarial parasites) in the blood. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Furthermore, these compounds distributed to target tissues (liver and spleen) and had a moderate oral bioavailability (up to 25%), a large volume of distribution, and an elimination half-life ranging from 1 to 2 days in mice." | 1.36 | Novel arylimidamides for treatment of visceral leishmaniasis. ( Boykin, DW; Hall, JE; Kyle, DE; Liu, Q; Madhubala, R; Mandal, S; Munde, M; Pandharkar, T; Parman, T; Riccio, E; Srivastava, A; Stephens, CE; Sweat, JM; Tidwell, RR; Wang, MZ; Werbovetz, KA; Wilson, WD; Zhu, X, 2010) |
| "Without treatment, visceral leishmaniasis is inevitably fatal." | 1.35 | Highly effective oral amphotericin B formulation against murine visceral leishmaniasis. ( Clement, JG; Gershkovich, P; Thornton, SJ; Tidwell, RR; Wasan, EK; Wasan, KM; Werbovetz, KA; Zhu, X, 2009) |
| " We therefore examined the possibility of minimizing these effects by applying miltefosine in lower doses in combination with picrloviv, an immunomodulator against Leishmania donovani in hamsters (Mesocricetus auratus)." | 1.33 | Efficacy of picroliv in combination with miltefosine, an orally effective antileishmanial drug against experimental visceral leishmaniasis. ( Gupta, S; Ramesh, SC; Srivastava, VM, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, MZ | 2 |
| Zhu, X | 3 |
| Srivastava, A | 1 |
| Liu, Q | 1 |
| Sweat, JM | 1 |
| Pandharkar, T | 2 |
| Stephens, CE | 1 |
| Riccio, E | 1 |
| Parman, T | 1 |
| Munde, M | 1 |
| Mandal, S | 1 |
| Madhubala, R | 1 |
| Tidwell, RR | 2 |
| Wilson, WD | 1 |
| Boykin, DW | 2 |
| Hall, JE | 1 |
| Kyle, DE | 1 |
| Werbovetz, KA | 3 |
| Benitez, D | 1 |
| Cabrera, M | 1 |
| Hernández, P | 1 |
| Boiani, L | 1 |
| Lavaggi, ML | 1 |
| Di Maio, R | 1 |
| Yaluff, G | 1 |
| Serna, E | 1 |
| Torres, S | 1 |
| Ferreira, ME | 1 |
| Vera de Bilbao, N | 1 |
| Torres, E | 1 |
| Pérez-Silanes, S | 1 |
| Solano, B | 1 |
| Moreno, E | 1 |
| Aldana, I | 1 |
| López de Ceráin, A | 1 |
| Cerecetto, H | 1 |
| González, M | 1 |
| Monge, A | 1 |
| Farahat, AA | 1 |
| Mattamana, M | 1 |
| Joice, A | 1 |
| Holt, E | 1 |
| Banerjee, M | 1 |
| Gragg, JL | 1 |
| Hu, L | 1 |
| Kumar, A | 1 |
| Yang, S | 1 |
| Gulin, JEN | 1 |
| Bisio, MMC | 1 |
| Rocco, D | 1 |
| Altcheh, J | 1 |
| Solana, ME | 1 |
| García-Bournissen, F | 1 |
| AbouLaila, M | 1 |
| Batadoj, D | 1 |
| Salama, A | 1 |
| Munkhjargal, T | 1 |
| Ichikawa-Seki, M | 1 |
| A Terkawi, M | 1 |
| Yokoyama, N | 1 |
| Igarashi, I | 1 |
| Wasan, KM | 1 |
| Wasan, EK | 1 |
| Gershkovich, P | 1 |
| Clement, JG | 1 |
| Thornton, SJ | 1 |
| Gupta, S | 1 |
| Ramesh, SC | 1 |
| Srivastava, VM | 1 |
7 other studies available for miltefosine and Parasitemia
| Article | Year |
|---|---|
Novel arylimidamides for treatment of visceral leishmaniasis.
Topics: Amidines; Animals; Antiprotozoal Agents; Biological Availability; Cricetinae; Disease Models, Animal | 2010 |
3-Trifluoromethylquinoxaline N,N'-dioxides as anti-trypanosomatid agents. Identification of optimal anti-T. cruzi agents and mechanism of action studies.
Topics: Animals; Chemistry, Pharmaceutical; Cyclic N-Oxides; Drug Design; Electrons; Humans; Inhibitory Conc | 2011 |
Synthesis and pharmacological evaluation of mono-arylimidamides as antileishmanial agents.
Topics: Administration, Oral; Animals; Antiprotozoal Agents; Chemistry Techniques, Synthetic; Drug Evaluatio | 2016 |
Miltefosine and Benznidazole Combination Improve Anti-
Topics: Animals; Chagas Disease; Mice; Nitroimidazoles; Parasitemia; Phosphorylcholine; Trypanocidal Agents; | 2022 |
Evaluation of the inhibitory effects of miltefosine on the growth of Babesia and Theileria parasites.
Topics: Animals; Antiparasitic Agents; Babesia; Babesiosis; Choline-Phosphate Cytidylyltransferase; Female; | 2014 |
Highly effective oral amphotericin B formulation against murine visceral leishmaniasis.
Topics: Administration, Oral; Amphotericin B; Animals; Antiprotozoal Agents; Chemistry, Pharmaceutical; Dose | 2009 |
Efficacy of picroliv in combination with miltefosine, an orally effective antileishmanial drug against experimental visceral leishmaniasis.
Topics: Adjuvants, Immunologic; Animals; Antiprotozoal Agents; Biopsy; Cinnamates; Cricetinae; Drug Interact | 2005 |