Page last updated: 2024-10-28

miltefosine and Mycoses

miltefosine has been researched along with Mycoses in 9 studies

miltefosine: hexadecyl phosphocholine derivative of cisplatin; did not substantially activate HIV long terminal repeat; less toxic than cisplatin
miltefosine : A phospholipid that is the hexadecyl monoester of phosphocholine.

Mycoses: Diseases caused by FUNGI.

Research Excerpts

ExcerptRelevanceReference
"Miltefosine is an alkylphosphocholine that shows broad-spectrum in vitro antifungal activities and limited in vivo efficacy in mouse models of cryptococcosis."3.79Synthesis and antifungal activities of miltefosine analogs. ( Agarwal, AK; Chen, YL; Clark, AM; Heitman, J; Jacob, MR; Khan, SI; Li, XC; Pan, X; Ravu, RR, 2013)
"Fungal infections are a global health problem with high mortality and morbidity rates."3.01Miltefosine repositioning: A review of potential alternative antifungal therapy. ( Borba-Santos, LP; Ishida, K; Rozental, S; Spadari, CC, 2023)
" This study determined the in vitro susceptibility of miltefosine, as a single agent and in combination with posaconazole or voriconazole, against these pathogens."1.39In vitro activity of miltefosine as a single agent and in combination with voriconazole or posaconazole against uncommon filamentous fungal pathogens. ( Biswas, C; Chen, SC; Djordjevic, JT; Jolliffe, KA; Sorrell, TC; Zuo, X, 2013)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's7 (77.78)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Ravu, RR1
Chen, YL1
Jacob, MR1
Pan, X1
Agarwal, AK1
Khan, SI1
Heitman, J1
Clark, AM1
Li, XC1
Wu, S1
Wang, Y2
Liu, N2
Dong, G2
Sheng, C2
Tu, J1
Spadari, CC1
Borba-Santos, LP1
Rozental, S1
Ishida, K1
Quaesaet, L1
Stindel, E1
Lanternier, F1
Williams, T1
Jaffuel, S1
Moalic, E1
Garcia Hermoso, D1
Lortholary, O1
Ansart, S1
Biswas, C1
Sorrell, TC2
Djordjevic, JT1
Zuo, X1
Jolliffe, KA1
Chen, SC1
Compain, F1
Botterel, F1
Sitterlé, E1
Paugam, A1
Bougnoux, ME1
Dannaoui, E1
Kesson, AM1
Bellemore, MC1
O'Mara, TJ1
Ellis, DH1
Ferguson, LM1
Dreisbach, AW1
Csongrádi, E1
Juncos, LA1
Fulop, T1

Reviews

3 reviews available for miltefosine and Mycoses

ArticleYear
Tackling Fungal Resistance by Biofilm Inhibitors.
    Journal of medicinal chemistry, 2017, 03-23, Volume: 60, Issue:6

    Topics: Animals; Antifungal Agents; Biofilms; Drug Discovery; Drug Resistance, Fungal; Fungi; Humans; Models

2017
Emerging New Targets for the Treatment of Resistant Fungal Infections.
    Journal of medicinal chemistry, 2018, 07-12, Volume: 61, Issue:13

    Topics: Antifungal Agents; Drug Resistance, Fungal; Humans; Molecular Targeted Therapy; Mycoses

2018
Miltefosine repositioning: A review of potential alternative antifungal therapy.
    Journal de mycologie medicale, 2023, Volume: 33, Issue:4

    Topics: Animals; Antifungal Agents; Drug Repositioning; Mycoses; Phosphorylcholine

2023

Other Studies

6 other studies available for miltefosine and Mycoses

ArticleYear
Synthesis and antifungal activities of miltefosine analogs.
    Bioorganic & medicinal chemistry letters, 2013, Sep-01, Volume: 23, Issue:17

    Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Candida; Candidiasis; Cell Line; C

2013
Miltefosine-based regimen as salvage therapy in Lomentospora prolificans bone and joint infection.
    Medecine et maladies infectieuses, 2018, Volume: 48, Issue:1

    Topics: Aged; Antifungal Agents; Arthritis, Infectious; Humans; Male; Mycoses; Osteomyelitis; Phosphorylchol

2018
In vitro activity of miltefosine as a single agent and in combination with voriconazole or posaconazole against uncommon filamentous fungal pathogens.
    The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:12

    Topics: Antifungal Agents; Drug Synergism; Fungi; Humans; Microbial Sensitivity Tests; Mycoses; Phosphorylch

2013
In vitro activity of miltefosine in combination with voriconazole or amphotericin B against clinical isolates of Scedosporium spp.
    Journal of medical microbiology, 2015, Volume: 64, Issue:Pt 3

    Topics: Amphotericin B; Antifungal Agents; Drug Therapy, Combination; Humans; Microbial Sensitivity Tests; M

2015
Scedosporium prolificans osteomyelitis in an immunocompetent child treated with a novel agent, hexadecylphospocholine (miltefosine), in combination with terbinafine and voriconazole: a case report.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2009, May-01, Volume: 48, Issue:9

    Topics: Antifungal Agents; Child; Drug Therapy, Combination; Female; Fractures, Bone; Humans; Mycoses; Napht

2009
Recurring extracorporeal circuit clotting during continuous renal replacement therapy in fungal sepsis: successful treatment with argatroban.
    The American journal of the medical sciences, 2013, Volume: 345, Issue:3

    Topics: Antifungal Agents; Antithrombins; Arginine; Blood Coagulation; Coronary Artery Bypass; Humans; Male;

2013