miltefosine has been researched along with Leukocytosis in 3 studies
miltefosine: hexadecyl phosphocholine derivative of cisplatin; did not substantially activate HIV long terminal repeat; less toxic than cisplatin
miltefosine : A phospholipid that is the hexadecyl monoester of phosphocholine.
Leukocytosis: A transient increase in the number of leukocytes in a body fluid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "34 patients with metastatic colorectal cancer were treated with the ether lipid miltefosine (hexadecylphosphocholine)." | 9.07 | Phase II study of daily oral miltefosine (hexadecylphosphocholine) in advanced colorectal cancer. ( Planting, AS; Stoter, G; Verweij, J, 1993) |
| "34 patients with metastatic colorectal cancer were treated with the ether lipid miltefosine (hexadecylphosphocholine)." | 5.07 | Phase II study of daily oral miltefosine (hexadecylphosphocholine) in advanced colorectal cancer. ( Planting, AS; Stoter, G; Verweij, J, 1993) |
| " In addition, at the highest dosage group in rats, an increase in white blood cell counts (WBC) was observed." | 2.67 | Increases in leucocyte and platelet counts induced by the alkyl phospholipid hexadecylphosphocholine. ( Drogendijk, TE; Oosterom, R; Planting, AS; Pronk, LC; Stoter, G; Verweij, J, 1994) |
| " A dose-response relationship was seen after daily oral treatment with complete suppression of tumor growth at doses of 46." | 1.27 | Characterization of the antitumor activity of hexadecylphosphocholine (D 18506). ( Berger, MR; Eibl, H; Engel, J; Hilgard, P; Schumacher, W; Stekar, J; Unger, C; Voegeli, R, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pronk, LC | 1 |
| Planting, AS | 2 |
| Oosterom, R | 1 |
| Drogendijk, TE | 1 |
| Stoter, G | 2 |
| Verweij, J | 2 |
| Hilgard, P | 1 |
| Stekar, J | 1 |
| Voegeli, R | 1 |
| Engel, J | 1 |
| Schumacher, W | 1 |
| Eibl, H | 1 |
| Unger, C | 1 |
| Berger, MR | 1 |
2 trials available for miltefosine and Leukocytosis
| Article | Year |
|---|---|
Increases in leucocyte and platelet counts induced by the alkyl phospholipid hexadecylphosphocholine.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Carcinoma, | 1994 |
Phase II study of daily oral miltefosine (hexadecylphosphocholine) in advanced colorectal cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Colorectal Neoplasms; Female; Humans; Leuk | 1993 |
1 other study available for miltefosine and Leukocytosis
| Article | Year |
|---|---|
Characterization of the antitumor activity of hexadecylphosphocholine (D 18506).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzopyrenes; Choline; Cyclophosphamide; Dose-Response Re | 1988 |