miltefosine has been researched along with Leukemia in 5 studies
miltefosine: hexadecyl phosphocholine derivative of cisplatin; did not substantially activate HIV long terminal repeat; less toxic than cisplatin
miltefosine : A phospholipid that is the hexadecyl monoester of phosphocholine.
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| "D-19391 was added to the SK-BR-3 breast cancer cell line and HePC to the Molt-4 leukemia cell line in concentrations of, respectively, 18." | 1.30 | Cellular uptake and retention measurements of alkylphosphocholines in the SK-BR-3 breast cancer and Molt-4 leukemia cell line using capillary gas chromatography. ( Brochez, V; De Potter, CR; Diniz, JA; Van den Eeckhout, EG; Van Heuverswyn, D, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Berkovic, D | 3 |
| Berkovic, K | 1 |
| Fleer, EA | 3 |
| Eibl, H | 2 |
| Unger, C | 2 |
| Goeckenjan, M | 1 |
| Lüders, S | 1 |
| Hiddemann, W | 2 |
| Haase, D | 1 |
| Brochez, V | 1 |
| Van Heuverswyn, D | 1 |
| Diniz, JA | 1 |
| De Potter, CR | 1 |
| Van den Eeckhout, EG | 1 |
| Hochhuth, C | 1 |
| Doenecke, D | 1 |
5 other studies available for miltefosine and Leukemia
| Article | Year |
|---|---|
Inhibition of calcium-dependent protein kinase C by hexadecylphosphocholine and 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine do not correlate with inhibition of proliferation of HL60 and K562 cell lines.
Topics: Antineoplastic Agents; Cell Division; Cell Membrane; Cytosol; Diglycerides; Dose-Response Relationsh | 1994 |
Hexadecylphosphocholine inhibits phosphatidylinositol and phosphatidylcholine phospholipase C in human leukemia cells.
Topics: Antineoplastic Agents; Cell Membrane; Cells, Cultured; Chromatography, Thin Layer; Enzyme Activation | 1996 |
Induction of resistance in the human leukemia cell line HL60 towards hexadecylphosphocholine and other ether phospholipid analogues.
Topics: Antigens, Surface; Antineoplastic Agents; Cholesterol; Chromosomes; Drug Resistance, Neoplasm; Flow | 1996 |
Cellular uptake and retention measurements of alkylphosphocholines in the SK-BR-3 breast cancer and Molt-4 leukemia cell line using capillary gas chromatography.
Topics: Antineoplastic Agents; Breast Neoplasms; Chromatography, Gas; Humans; Leukemia; Phosphorylcholine; R | 1999 |
Early effects of hexadecylphosphocholine on gene expression in leukemia cell lines.
Topics: Antineoplastic Agents; Humans; Leukemia; Phosphorylcholine; Transcription, Genetic; Tumor Cells, Cul | 1992 |