miltefosine has been researched along with Inflammation in 7 studies
miltefosine: hexadecyl phosphocholine derivative of cisplatin; did not substantially activate HIV long terminal repeat; less toxic than cisplatin
miltefosine : A phospholipid that is the hexadecyl monoester of phosphocholine.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to report a retrospective case series of anterior scleral and limbal inflammatory necrosis after adjuvant miltefosine for recalcitrant Acanthamoeba keratitis (AK)." | 8.12 | Anterior Scleral and Limbal Inflammatory Necrosis After Adjuvant Miltefosine for Recalcitrant Acanthamoeba Keratitis. ( Berdahl, J; de la Presa, M; Holland, EJ; Ibach, M, 2022) |
| "We tested the effect of miltefosine on the activation of human eosinophils and their effector responses in vitro and in mouse models of eosinophilic migration and ovalbumin-induced allergic lung inflammation." | 8.02 | The anti-parasitic drug miltefosine suppresses activation of human eosinophils and ameliorates allergic inflammation in mice. ( Heinemann, A; Kienzl, M; Knuplez, E; Marsche, G; Schicho, R; Sturm, EM; Trakaki, A, 2021) |
| "Miltefosine inhibits T-cell proliferation and effectively reduces inflammation in the T-cell transfer model." | 7.79 | Miltefosine suppresses inflammation in a mouse model of inflammatory bowel disease. ( Duijvestein, M; Hommes, DW; Meijer, SL; Peppelenbosch, MP; te Velde, AA; van den Brink, GR; Verhaar, AP; Vos, AC; Wildenberg, ME, 2013) |
| "We demonstrate that miltefosine is locally active in patients with AD and led to a sustained clinical improvement in local skin inflammation." | 5.14 | Long-term reduction in local inflammation by a lipid raft molecule in atopic dermatitis. ( Dölle, S; Hoser, D; Loddenkemper, C; Maurer, M; Rasche, C; Worm, M; Zuberbier, T, 2010) |
| "The purpose of this study was to report a retrospective case series of anterior scleral and limbal inflammatory necrosis after adjuvant miltefosine for recalcitrant Acanthamoeba keratitis (AK)." | 4.12 | Anterior Scleral and Limbal Inflammatory Necrosis After Adjuvant Miltefosine for Recalcitrant Acanthamoeba Keratitis. ( Berdahl, J; de la Presa, M; Holland, EJ; Ibach, M, 2022) |
| "We tested the effect of miltefosine on the activation of human eosinophils and their effector responses in vitro and in mouse models of eosinophilic migration and ovalbumin-induced allergic lung inflammation." | 4.02 | The anti-parasitic drug miltefosine suppresses activation of human eosinophils and ameliorates allergic inflammation in mice. ( Heinemann, A; Kienzl, M; Knuplez, E; Marsche, G; Schicho, R; Sturm, EM; Trakaki, A, 2021) |
| "Miltefosine inhibits T-cell proliferation and effectively reduces inflammation in the T-cell transfer model." | 3.79 | Miltefosine suppresses inflammation in a mouse model of inflammatory bowel disease. ( Duijvestein, M; Hommes, DW; Meijer, SL; Peppelenbosch, MP; te Velde, AA; van den Brink, GR; Verhaar, AP; Vos, AC; Wildenberg, ME, 2013) |
| " This alkylphospholipid was also extremely toxic against intracellular amastigotes of both strains." | 1.31 | Proinflammatory and cytotoxic effects of hexadecylphosphocholine (miltefosine) against drug-resistant strains of Trypanosoma cruzi. ( Bozza, MT; Freire-De-Lima, CG; Gibaldi, D; Heise, N; Mendonça-Previato, L; Previato, JO; Saraiva, VB, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| de la Presa, M | 1 |
| Ibach, M | 1 |
| Berdahl, J | 1 |
| Holland, EJ | 1 |
| Pisipati, S | 1 |
| Connor, BA | 1 |
| Riddle, MS | 1 |
| Knuplez, E | 1 |
| Kienzl, M | 1 |
| Trakaki, A | 1 |
| Schicho, R | 1 |
| Heinemann, A | 1 |
| Sturm, EM | 1 |
| Marsche, G | 1 |
| Verhaar, AP | 1 |
| Wildenberg, ME | 1 |
| te Velde, AA | 1 |
| Meijer, SL | 1 |
| Vos, AC | 1 |
| Duijvestein, M | 1 |
| Peppelenbosch, MP | 1 |
| Hommes, DW | 1 |
| van den Brink, GR | 1 |
| Bäumer, W | 1 |
| Wlaź, P | 1 |
| Jennings, G | 1 |
| Rundfeldt, C | 1 |
| Dölle, S | 1 |
| Hoser, D | 1 |
| Rasche, C | 1 |
| Loddenkemper, C | 1 |
| Maurer, M | 1 |
| Zuberbier, T | 1 |
| Worm, M | 1 |
| Saraiva, VB | 1 |
| Gibaldi, D | 1 |
| Previato, JO | 1 |
| Mendonça-Previato, L | 1 |
| Bozza, MT | 1 |
| Freire-De-Lima, CG | 1 |
| Heise, N | 1 |
1 review available for miltefosine and Inflammation
| Article | Year |
|---|---|
Updates on the epidemiology, pathogenesis, diagnosis, and management of postinfectious irritable bowel syndrome.
Topics: Adult; Animals; Anti-Bacterial Agents; Child; Colon; Gastroenteritis; Humans; Infections; Inflammati | 2020 |
1 trial available for miltefosine and Inflammation
| Article | Year |
|---|---|
Long-term reduction in local inflammation by a lipid raft molecule in atopic dermatitis.
Topics: Administration, Topical; Adolescent; Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents; Derma | 2010 |
5 other studies available for miltefosine and Inflammation
| Article | Year |
|---|---|
Anterior Scleral and Limbal Inflammatory Necrosis After Adjuvant Miltefosine for Recalcitrant Acanthamoeba Keratitis.
Topics: Acanthamoeba Keratitis; Adjuvants, Immunologic; Adult; Humans; Inflammation; Necrosis; Phosphorylcho | 2022 |
The anti-parasitic drug miltefosine suppresses activation of human eosinophils and ameliorates allergic inflammation in mice.
Topics: Animals; Eosinophils; Humans; Inflammation; Mice; Ovalbumin; Parasites; Pharmaceutical Preparations; | 2021 |
Miltefosine suppresses inflammation in a mouse model of inflammatory bowel disease.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Cytokines; Disease Models, Animal; Humans; Immun | 2013 |
The putative lipid raft modulator miltefosine displays immunomodulatory action in T-cell dependent dermal inflammation models.
Topics: Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents; Arachidonic Acid; | 2010 |
Proinflammatory and cytotoxic effects of hexadecylphosphocholine (miltefosine) against drug-resistant strains of Trypanosoma cruzi.
Topics: Animals; Antiprotozoal Agents; Chagas Disease; Drug Resistance; Exudates and Transudates; Inflammati | 2002 |