Page last updated: 2024-10-28

miltefosine and Glioma

miltefosine has been researched along with Glioma in 3 studies

miltefosine: hexadecyl phosphocholine derivative of cisplatin; did not substantially activate HIV long terminal repeat; less toxic than cisplatin
miltefosine : A phospholipid that is the hexadecyl monoester of phosphocholine.

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
"Treatment with miltefosine resulted in increase in Ras, extracellular signal-regulated kinase (ERK) and p38MAPK activity."5.35Involvement of miltefosine-mediated ERK activation in glioma cell apoptosis through Fas regulation. ( Koul, N; Sen, E; Sharma, V; Tewari, R, 2008)
"Treatment with miltefosine resulted in increase in Ras, extracellular signal-regulated kinase (ERK) and p38MAPK activity."1.35Involvement of miltefosine-mediated ERK activation in glioma cell apoptosis through Fas regulation. ( Koul, N; Sen, E; Sharma, V; Tewari, R, 2008)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Sandbhor, P1
Goda, JS1
Mohanty, B1
Chaudhari, P1
Dutt, S1
Banerjee, R1
Tewari, R1
Sharma, V1
Koul, N1
Sen, E1
Zeller, WJ1
Bauer, S1
Remmele, T1
Wowra, B1
Sturm, V1
Stricker, H1

Other Studies

3 other studies available for miltefosine and Glioma

ArticleYear
Bio-polymeric transferrin-targeted temozolomide nanoparticles in gel for synergistic post-surgical GBM therapy.
    Nanoscale, 2022, Sep-15, Volume: 14, Issue:35

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Delayed-Action Preparations; Glioblastoma; Glioma; Hydro

2022
Involvement of miltefosine-mediated ERK activation in glioma cell apoptosis through Fas regulation.
    Journal of neurochemistry, 2008, Volume: 107, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Line, Tumor; Enzyme Activation; Extracellu

2008
Interstitial chemotherapy of experimental gliomas.
    Cancer treatment reviews, 1990, Volume: 17, Issue:2-3

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Drug Carriers; Drug Screening Assays, Antitumor; Gl

1990