miltefosine has been researched along with Encephalitis in 7 studies
miltefosine: hexadecyl phosphocholine derivative of cisplatin; did not substantially activate HIV long terminal repeat; less toxic than cisplatin
miltefosine : A phospholipid that is the hexadecyl monoester of phosphocholine.
Encephalitis: Inflammation of the BRAIN due to infection, autoimmune processes, toxins, and other conditions. Viral infections (see ENCEPHALITIS, VIRAL) are a relatively frequent cause of this condition.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Miltefosine dosing for GAE has been based on leishmaniasis dosing because no data exist in humans concerning its pharmacologic distribution in the central nervous system." | 5.42 | Assessment of blood-brain barrier penetration of miltefosine used to treat a fatal case of granulomatous amebic encephalitis possibly caused by an unusual Balamuthia mandrillaris strain. ( Atkins, JT; Dorlo, TP; Gennuso, R; Guglielmo, BJ; Hayes, T; Kofos, D; Kucerova, Z; Qvarnstrom, Y; Roy, SL; Sriram, RR; Visvesvara, GS, 2015) |
| " Miltefosine dosing for GAE has been based on leishmaniasis dosing because no data exist in humans concerning its pharmacologic distribution in the central nervous system." | 1.42 | Assessment of blood-brain barrier penetration of miltefosine used to treat a fatal case of granulomatous amebic encephalitis possibly caused by an unusual Balamuthia mandrillaris strain. ( Atkins, JT; Dorlo, TP; Gennuso, R; Guglielmo, BJ; Hayes, T; Kofos, D; Kucerova, Z; Qvarnstrom, Y; Roy, SL; Sriram, RR; Visvesvara, GS, 2015) |
| "These infections include primary amebic meningoencephalitis (PAM) caused by Naegleria fowleri and granulomatous amebic encephalitis caused by Balamuthia mandrillaris and Acanthamoeba species." | 1.39 | Investigational drug available directly from CDC for the treatment of infections with free-living amebae. ( , 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roy, SL | 1 |
| Atkins, JT | 1 |
| Gennuso, R | 1 |
| Kofos, D | 1 |
| Sriram, RR | 1 |
| Dorlo, TP | 1 |
| Hayes, T | 1 |
| Qvarnstrom, Y | 2 |
| Kucerova, Z | 1 |
| Guglielmo, BJ | 1 |
| Visvesvara, GS | 4 |
| Kaul, DR | 1 |
| Lowe, L | 1 |
| Farmen, S | 1 |
| Khaled, YA | 1 |
| Yanik, GA | 1 |
| Aichelburg, AC | 1 |
| Walochnik, J | 2 |
| Assadian, O | 2 |
| Prosch, H | 1 |
| Steuer, A | 2 |
| Perneczky, G | 1 |
| Aspöck, H | 2 |
| Vetter, N | 2 |
| Martínez, DY | 1 |
| Seas, C | 1 |
| Bravo, F | 1 |
| Legua, P | 1 |
| Ramos, C | 1 |
| Cabello, AM | 1 |
| Gotuzzo, E | 1 |
| Webster, D | 1 |
| Umar, I | 2 |
| Kolyvas, G | 1 |
| Bilbao, J | 1 |
| Guiot, MC | 1 |
| Duplisea, K | 1 |
| Aichelburg, A | 1 |
| Visvesvara, G | 1 |
7 other studies available for miltefosine and Encephalitis
| Article | Year |
|---|---|
Investigational drug available directly from CDC for the treatment of infections with free-living amebae.
Topics: Acanthamoeba; Amebiasis; Animals; Antiprotozoal Agents; Balamuthia mandrillaris; Centers for Disease | 2013 |
Assessment of blood-brain barrier penetration of miltefosine used to treat a fatal case of granulomatous amebic encephalitis possibly caused by an unusual Balamuthia mandrillaris strain.
Topics: Amebiasis; Amebicides; Balamuthia mandrillaris; Blood-Brain Barrier; Brain; Child; Encephalitis; Fat | 2015 |
Acanthamoeba infection in a patient with chronic graft-versus-host disease occurring during treatment with voriconazole.
Topics: Acanthamoeba; Amebiasis; Animals; Antifungal Agents; Antiprotozoal Agents; Drug Therapy, Combination | 2008 |
Successful treatment of disseminated Acanthamoeba sp. infection with miltefosine.
Topics: Acanthamoeba; Administration, Oral; Administration, Topical; Adult; Amebiasis; Animals; Antiprotozoa | 2008 |
Successful treatment of Balamuthia mandrillaris amoebic infection with extensive neurological and cutaneous involvement.
Topics: Adult; Aged; Albendazole; Amebiasis; Amoebozoa; Antiprotozoal Agents; Brain; Child; Child, Preschool | 2010 |
Treatment of granulomatous amoebic encephalitis with voriconazole and miltefosine in an immunocompetent soldier.
Topics: Acanthamoeba; Adult; Amebiasis; Animals; Encephalitis; Granuloma; Humans; Immunocompetence; Male; Mi | 2012 |
Granulomatous amoebic encephalitis caused by Acanthamoeba amoebae of genotype T2 in a human immunodeficiency virus-negative patient.
Topics: Acanthamoeba; Adult; Amebiasis; Amikacin; Animals; Antiprotozoal Agents; Antitubercular Agents; DNA, | 2008 |