Page last updated: 2024-10-28

miltefosine and Dermatitis, Atopic

miltefosine has been researched along with Dermatitis, Atopic in 2 studies

miltefosine: hexadecyl phosphocholine derivative of cisplatin; did not substantially activate HIV long terminal repeat; less toxic than cisplatin
miltefosine : A phospholipid that is the hexadecyl monoester of phosphocholine.

Dermatitis, Atopic: A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.

Research Excerpts

ExcerptRelevanceReference
"We demonstrate that miltefosine is locally active in patients with AD and led to a sustained clinical improvement in local skin inflammation."5.14Long-term reduction in local inflammation by a lipid raft molecule in atopic dermatitis. ( Dölle, S; Hoser, D; Loddenkemper, C; Maurer, M; Rasche, C; Worm, M; Zuberbier, T, 2010)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dölle, S1
Hoser, D1
Rasche, C1
Loddenkemper, C1
Maurer, M2
Zuberbier, T1
Worm, M1
Magerl, M1
Metz, M1
Weller, K1
Siebenhaar, F1

Reviews

1 review available for miltefosine and Dermatitis, Atopic

ArticleYear
Miltefosine: a novel treatment option for mast cell-mediated diseases.
    The Journal of dermatological treatment, 2013, Volume: 24, Issue:4

    Topics: Antineoplastic Agents; Dermatitis, Atopic; Humans; Mast Cells; Mastocytosis; Phosphorylcholine; Urti

2013

Trials

1 trial available for miltefosine and Dermatitis, Atopic

ArticleYear
Long-term reduction in local inflammation by a lipid raft molecule in atopic dermatitis.
    Allergy, 2010, Volume: 65, Issue:9

    Topics: Administration, Topical; Adolescent; Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents; Derma

2010